Chronic Myelogenous Leukemia (CML)

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10 Questions

Which of the following is a characteristic of Chronic Myelogenous Leukemia (CML)?

Presence of the Philadelphia chromosome t(9,22)

What is the median age of patients with CML?

50 years

Which phase of CML is characterized by an abrupt increase in basophils and blast cells?

Accelerated phase

What are the typical signs and symptoms of CML?

LUQ pain and early satiety

Without treatment, how long does the chronic phase of CML typically last?

3.5-5.0 years

Which of the following is a common cause of oropharyngeal dysphagia?

Stroke

What is the best initial test for diagnosing esophageal dysphagia?

Esophagogastroduodenoscopy (EGD)

Which of the following is a common motility disorder that can cause esophageal dysphagia?

Scleroderma

What type of food is usually more problematic for patients with oropharyngeal dysphagia?

Liquids

What type of food is usually more problematic for patients with obstructions causing esophageal dysphagia?

Solids

Test your knowledge on Chronic Myelogenous Leukemia (CML), a condition characterized by clonal expansion of myeloid progenitor cells. This quiz covers key information on symptoms, diagnosis, and treatment options for CML, including the importance of the BCR-ABL translocation and the Philadelphia chromosome. Challenge yourself and learn more about this hematologic disorder.

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