Chronic Inflammation Quiz

<p>Fever, lethargy, weight loss</p> Signup and view all the answers

<p>To eliminate the pathogenic material</p> Signup and view all the answers

<p>Foreign material</p> Signup and view all the answers

<p>Macrophages and dendritic cells</p> Signup and view all the answers

<p>Proline</p> Signup and view all the answers

<p>M1 Cells and M2 Cells</p> Signup and view all the answers

<p>C-reactive proteins</p> Signup and view all the answers

<p>Chronic progressive interstitial nephritis</p> Signup and view all the answers

<p>Infectious agents/infectious disease</p> Signup and view all the answers

<p>Lymphocytes and plasma cells</p> Signup and view all the answers

<p>Diffuse interstitial fibrosis, tubular atrophy, and stippled red bands</p> Signup and view all the answers

<p>Pattern of fibrosis</p> Signup and view all the answers

<p>Antibiotics</p> Signup and view all the answers

<p>No</p> Signup and view all the answers

<p>Chronic kidney disease</p> Signup and view all the answers

<p>Contracted glomeruli with thickened Bowman's capsules</p> Signup and view all the answers

<p>Interstitial fibrosis</p> Signup and view all the answers

<p>Infectious granuloma</p> Signup and view all the answers

<p>Chronic inflammation</p> Signup and view all the answers

<p>M2 subtype</p> Signup and view all the answers

<p>Johnes Disease</p> Signup and view all the answers

<p>Chronic granulomatous disease</p> Signup and view all the answers

<p>Hydronephrosis</p> Signup and view all the answers

<p>Lung pyogranuloma</p> Signup and view all the answers

<p>Immune mediated arteritis</p> Signup and view all the answers

<p>Macrophages = Main cell type in chronic inflammation M1 Cells = Convert arginine to nitric oxide which is toxic to phagocytosed organisms M2 Cells = Convert arginine to ornithine which promotes proline in extracellular fluid, a precursor for collagen synthesis IL1 and IL6 = Pro-inflammatory cytokines associated with systemic illness and chronic inflammation</p> Signup and view all the answers

<p>Persistent stimulus = Inflammatory initiators that cannot be eliminated leading to the formation of a granuloma Necrotic center = Made of foreign material, and the body responds to eliminate this by phagocytosing this Granuloma = Formed when there is a persistent stimulus, causing distinct arrangement of inflammatory cells to prevent dissemination of the stimulus C reactive proteins = Acute phase proteins that may be immunosuppressive and are indicators of chronic inflammation in blood</p> Signup and view all the answers

<p>Pyrexia = A symptom caused by pro-inflammatory cytokines like IL1 and IL6 Lethargy = A symptom caused by pro-inflammatory cytokines like IL1 and IL6 Weight loss = A symptom caused by pro-inflammatory cytokines like IL1 and IL6 Giant cells = Produced to separate the necrotic center from the body in a granuloma</p> Signup and view all the answers

<p>Chronic hepatitis in cow = Infections, toxic or idiopathic with symptoms like weight loss, lethargy and depression Johnes Disease = Granulatomous lesions in the lymph node, circular mass of cells Feline infectious peritonitis = Pyogranulomatous lesions, prevalent in young cats less than 2 years of age Actinobacillosis = Bacterial cause, increased salivation and difficulty chewing, chronic inflammatory case</p> Signup and view all the answers

<p>Granuloma = Cellular attempt to contain an offending agent that is difficult to eradicate Pyogranuloma = Chronic inflammatory lesion characterised by predominance of macrophages and neutrophils Chronic granulomatous disease = Inherited disorder that occurs when the phagocytes don't work properly Hydronephrosis = Kidneys have become swollen and stretched due to urine build up</p> Signup and view all the answers

<p>Chronic mastitis = Tuberculosis - mycobacterium bovis Lung pyogranuloma in dog = Grey nodules varying in size throughout the lung parachyma Immune mediated arteritis = Pathogenic cause such as parvovirus 2 in younger dog Chronic pyelonephritis in the dogs kidney = Example of Pyogenic Granulomas</p> Signup and view all the answers

<p>Chronic Interstitial nephritis (Cat) = Characterised by multiple large, irregular and pale grey subcapsular cortical foci Acute interstitial nephritis (Cat) = Uncommon in cats Chronic progressive interstitial nephritis (Cat) = More commonly referred to as chronic kidney disease Chronic interstitial nephritis (Dog) = Characterised by interstitial fibrosis, Tubular atrophy</p> Signup and view all the answers

<p>Chronic Interstitial nephritis (Cat) = Caused by infectious agents/ infectious disease Chronic interstitial nephritis (Dog) = Characterised by contracted glomeruli with thickened bowman's capsules Chronic progressive interstitial nephritis (Cat) = Common in cats</p> Signup and view all the answers

<p>Chronic Interstitial nephritis (Cat) = Antibiotics might be used if infectious disease is diagnosed Chronic interstitial nephritis (Dog) = Characterised by Bands of grey fibrous tissue surrounding islands of the renal cortex Chronic progressive interstitial nephritis (Cat) = Caused by infectious agents/ infectious disease</p> Signup and view all the answers

<p>Chronic Interstitial nephritis (Cat) = Immune response has caused a granulomatous vasculitis and developed renal intersisital pyogranuloma Chronic interstitial nephritis (Dog) = Characterised by Stippled red Bands of grey fibrous tissue surrounding islands of the renal cortex Chronic progressive interstitial nephritis (Cat) = Common in cats and are more commonly referred to as chronic kidney disease</p> Signup and view all the answers