10 Questions
Which cytokine facilitates B-cell class switching to IgG and IgE?
IL-4
Which cells express MHC class I and can present intracellular antigens?
All nucleated cells and platelets
Which cytokine is secreted by CD4+ T H 1 cells to provide the second activation signal for cytotoxic T-cell activation?
IL-2
What is the characteristic feature of noncaseating granulomas?
Lack of central necrosis
What induces the differentiation of CD4+ helper T cells into T H1 subtype in granulomatous inflammation?
IL-12
Which of the following is a characteristic of chronic inflammation?
Presence of lymphocytes and plasma cells in tissue
What is the main cause of stimuli for chronic inflammation?
Persistent infection
Where are T cells produced as progenitor cells?
Bone marrow
Which subset of activated CD4+ helper T cells secretes IL-2 and IFN-y?
$T_H1$ subset
What is the role of B7 on antigen presenting cells (APCs) in T cell activation?
Binds CD25 on CD4+ helper T cells providing 2nd activation signal
Test your knowledge of chronic inflammation with this quiz. Learn about the characteristics, causes, and immune response involved in this type of inflammation.
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