Chronic Inflammation Quiz
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Questions and Answers

Which cytokine facilitates B-cell class switching to IgG and IgE?

  • IL-12
  • IL-5
  • IL-4 (correct)
  • IL-10

    • Which cells express MHC class I and can present intracellular antigens?

  • All nucleated cells and platelets (correct)
  • Neutrophils and monocytes
  • Macrophages and dendritic cells
  • Eosinophils and basophils

    • Which cytokine is secreted by CD4+ T H 1 cells to provide the second activation signal for cytotoxic T-cell activation?

  • IL-4
  • IL-10
  • IL-5
  • IL-2 (correct)

    • What is the characteristic feature of noncaseating granulomas?

    <p>Lack of central necrosis</p> Signup and view all the answers

    What induces the differentiation of CD4+ helper T cells into T H1 subtype in granulomatous inflammation?

    <p>IL-12</p> Signup and view all the answers

    Which of the following is a characteristic of chronic inflammation?

    <p>Presence of lymphocytes and plasma cells in tissue</p> Signup and view all the answers

    What is the main cause of stimuli for chronic inflammation?

    <p>Persistent infection</p> Signup and view all the answers

    Where are T cells produced as progenitor cells?

    <p>Bone marrow</p> Signup and view all the answers

    Which subset of activated CD4+ helper T cells secretes IL-2 and IFN-y?

    <p>$T_H1$ subset</p> Signup and view all the answers

    What is the role of B7 on antigen presenting cells (APCs) in T cell activation?

    <p>Binds CD25 on CD4+ helper T cells providing 2nd activation signal</p> Signup and view all the answers

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