Chronic Inflammation Quiz

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Questions and Answers

Which cytokine facilitates B-cell class switching to IgG and IgE?

  • IL-12
  • IL-5
  • IL-4 (correct)
  • IL-10

Which cells express MHC class I and can present intracellular antigens?

  • All nucleated cells and platelets (correct)
  • Neutrophils and monocytes
  • Macrophages and dendritic cells
  • Eosinophils and basophils

Which cytokine is secreted by CD4+ T H 1 cells to provide the second activation signal for cytotoxic T-cell activation?

  • IL-4
  • IL-10
  • IL-5
  • IL-2 (correct)

What is the characteristic feature of noncaseating granulomas?

<p>Lack of central necrosis (A)</p> Signup and view all the answers

What induces the differentiation of CD4+ helper T cells into T H1 subtype in granulomatous inflammation?

<p>IL-12 (C)</p> Signup and view all the answers

Which of the following is a characteristic of chronic inflammation?

<p>Presence of lymphocytes and plasma cells in tissue (C)</p> Signup and view all the answers

What is the main cause of stimuli for chronic inflammation?

<p>Persistent infection (B)</p> Signup and view all the answers

Where are T cells produced as progenitor cells?

<p>Bone marrow (A)</p> Signup and view all the answers

Which subset of activated CD4+ helper T cells secretes IL-2 and IFN-y?

<p>$T_H1$ subset (C)</p> Signup and view all the answers

What is the role of B7 on antigen presenting cells (APCs) in T cell activation?

<p>Binds CD25 on CD4+ helper T cells providing 2nd activation signal (B)</p> Signup and view all the answers

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