Chronic Inflammation and Repair Quiz
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Questions and Answers

What is the definition of chronic inflammation?

  • Inflammation of prolonged duration (correct)
  • Inflammation caused by a specific pathogen
  • Inflammation that resolves without any attempt at repair
  • Inflammation of short duration
  • What are the two types of chronic inflammation based on the cause?

  • Bacterial and viral
  • Infective and non-infective
  • Non-specific and specific (correct)
  • De novo and acute
  • Which type of granuloma is characterized by the chief reactive cell being an activated macrophage?

  • Infective granuloma
  • Foreign body granuloma
  • Allergic granuloma
  • Non-infective granuloma (correct)
  • Which condition is an example of infective granuloma?

    <p>Lymphogranuloma inguinale</p> Signup and view all the answers

    What is the distinct pattern of chronic inflammation in which tiny granules fuse to form a tumor-like mass?

    <p>Granuloma</p> Signup and view all the answers

    Which condition is an example of non-infective granuloma?

    <p>Rheumatic fever</p> Signup and view all the answers

    Which type of wound healing occurs when wound edges cannot be apposed?

    <p>Secondary intention</p> Signup and view all the answers

    Which type of cell does not proliferate under normal conditions but only when there is a need?

    <p>Stable cells</p> Signup and view all the answers

    What is the process of replacement of the damaged tissue by granulation tissue which matures to fibrous tissue?

    <p>Organization healing</p> Signup and view all the answers

    Which factor delays wound healing and leads to more granulation tissue and scarring?

    <p>Infection</p> Signup and view all the answers

    What is the best example of healing by regeneration in humans?

    <p>Liver regeneration</p> Signup and view all the answers

    Which cells are continuously dividing throughout life to replace damaged cells?

    <p>Labile cells</p> Signup and view all the answers

    What type of inflammation heals by organization?

    <p>Serofibrinous inflammation</p> Signup and view all the answers

    Which type of repair involves the replacement of injured cells by cells of the same type?

    <p>Regenerative repair</p> Signup and view all the answers

    Study Notes

    Chronic Inflammation

    • Defined as a prolonged inflammatory response characterized by simultaneous tissue destruction and healing.
    • Can lead to various diseases and conditions if unresolved.

    Types of Chronic Inflammation

    • Infective Chronic Inflammation: Resulting from persistent infections, such as those caused by bacteria or viruses.
    • Non-Infective Chronic Inflammation: Triggered by factors like autoimmune diseases or chronic irritants.

    Granulomas

    • Caseating Granuloma: Activated macrophages are the primary reactive cells, often seen in infections like tuberculosis.
    • Infective Granuloma Example: Tuberculosis is a classic example related to caseating granulomas.

    Patterns of Chronic Inflammation

    • Distinct pattern includes granulomatous inflammation, where small granules fuse into a tumor-like mass, termed a granuloma.

    Non-Infective Granuloma Example

    • Sarcoidosis serves as a prominent example of non-infective granulomas, characterized by the collection of immune cells.

    Wound Healing

    • Secondary Intention Healing: Occurs when wound edges cannot be apposed, usually resulting in more extensive scarring.
    • Replacement of damaged tissue by granulation tissue evolving into fibrous tissue is termed organization.
    • Factors like infection or poor nutrition can delay wound healing and increase granulation tissue formation.

    Regeneration and Cell Division

    • Best example of healing by regeneration in humans is liver regeneration after partial hepatectomy.
    • Stem cells are responsible for continuous cell division, replacing damaged cells throughout life.

    Types of Inflammation and Repair

    • Organization: Healing process in inflammation characterized by the formation of granulation tissue during chronic inflammation.
    • Tissue Repair: Involves replacement of injured cells by the same type, known as regeneration.

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    Description

    Test your knowledge about chronic inflammation, tissue injury, and repair processes. Learn about the causes and types of chronic inflammation, including de novo and on top of acute inflammation.

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