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Questions and Answers
Which type of chronic inflammation starts on top of acute inflammation?
Which type of chronic inflammation starts on top of acute inflammation?
- Infective granuloma
- Foreign body granuloma
- De novo chronic inflammation (correct)
- Allergic granuloma
What is the characteristic feature of chronic inflammation?
What is the characteristic feature of chronic inflammation?
- Short duration (days)
- Absence of tissue injury
- Complete absence of repair attempts
- Inflammation that lasts for months (correct)
What is the chief reactive cell in a granuloma?
What is the chief reactive cell in a granuloma?
- Eosinophil
- Lymphocyte
- Neutrophil
- Activated macrophage (correct)
Which disease can lead to infective granuloma?
Which disease can lead to infective granuloma?
What happens to tiny granules in non-infective granulomas?
What happens to tiny granules in non-infective granulomas?
What is the characteristic feature of chronic non-specific inflammation?
What is the characteristic feature of chronic non-specific inflammation?
Which type of wound healing occurs when wound edges cannot be apposed?
Which type of wound healing occurs when wound edges cannot be apposed?
What is the characteristic feature of fibrosis in wound healing?
What is the characteristic feature of fibrosis in wound healing?
Which factor leads to delays in wound healing and more granulation tissue and scarring?
Which factor leads to delays in wound healing and more granulation tissue and scarring?
Which cells are continuously dividing throughout life to replace damaged cells?
Which cells are continuously dividing throughout life to replace damaged cells?
Which type of repair involves replacement of injured cells by cells of the same type?
Which type of repair involves replacement of injured cells by cells of the same type?
What is the best example of healing by regeneration in humans?
What is the best example of healing by regeneration in humans?
What does repair by fibrosis involve?
What does repair by fibrosis involve?
'Wound healing can occur by one of two ways according to the type of wound.' Which two ways are being referred to?
'Wound healing can occur by one of two ways according to the type of wound.' Which two ways are being referred to?
'Replacement of solid non living material as dead tissue, blood clots or fibrin by fibrous tissue' refers to:
'Replacement of solid non living material as dead tissue, blood clots or fibrin by fibrous tissue' refers to:
'What type of wound usually results in a large scar?'
'What type of wound usually results in a large scar?'
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Study Notes
Chronic Inflammation
- Chronic inflammation starts on top of acute inflammation
- The characteristic feature of chronic inflammation is the simultaneous destruction and healing of tissues
Granulomas
- The chief reactive cell in a granuloma is the epithelioid cell
- Infective granulomas can be caused by diseases such as tuberculosis
- In non-infective granulomas, tiny granules are engulfed by macrophages
Wound Healing
- Secondary intention healing occurs when wound edges cannot be apposed
- The characteristic feature of chronic non-specific inflammation is the presence of macrophages and lymphocytes
- Fibrosis in wound healing is characterized by the deposition of collagen
- Factors that lead to delays in wound healing and more granulation tissue and scarring include infection, diabetes, and poor circulation
Cell Regeneration
- Stem cells are continuously dividing throughout life to replace damaged cells
- Regenerative repair involves replacement of injured cells by cells of the same type
- The best example of healing by regeneration in humans is the liver
Repair by Fibrosis
- Repair by fibrosis involves the replacement of functional tissue with scar tissue
Types of Wound Healing
- Wound healing can occur by two ways: regeneration or repair by fibrosis
- Large wounds that result in a large scar are typically healed by secondary intention
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