Chromatography: Stationary Phases
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Questions and Answers

What is the chemical formula of silica gel?

  • SiO4
  • SiO3
  • SiO2 (correct)
  • SiO

How does the polarity of silica gel compare to alumina?

  • Silica gel is less polar than alumina. (correct)
  • Silica gel is more polar than alumina.
  • Silica gel and alumina have the same polarity.
  • Silica gel has no polarity, while alumina is polar.

What type of adsorbent is silica gel?

  • Acidic adsorbent (correct)
  • Basic adsorbent
  • Non-adsorbent
  • Neutral adsorbent

Which compounds does silica gel preferentially retain?

<p>Basic compounds (D)</p> Signup and view all the answers

What is the relationship between the polarity of silica gel and its adsorption properties?

<p>The lower the polarity of silica gel, the better it can adsorb basic compounds. (B)</p> Signup and view all the answers

What type of interactions does the compound exhibit?

<p>Dipole-dipole and H-bonding (C)</p> Signup and view all the answers

How do polar analytes interact with the stationary phase in TLC?

<p>They interact strongly with the stationary phase (A)</p> Signup and view all the answers

Why do polar analytes move very slowly up the TLC plate?

<p>Due to strong interactions with the stationary phase (C)</p> Signup and view all the answers

Which type of bonding is most likely responsible for the slow movement of polar analytes up the TLC plate?

<p>Hydrogen bonding (D)</p> Signup and view all the answers

What effect do dipole-dipole interactions have on the movement of polar analytes in TLC?

<p>Slows down their movement (B)</p> Signup and view all the answers

What are the 2 most common adsorbents used in chromatography?

<p>Porous alumina and porous silica gel (A)</p> Signup and view all the answers

Which material is NOT commonly used as an adsorbent in chromatography?

<p>Activated charcoal (A)</p> Signup and view all the answers

Which of the following is a common misconception about chromatography adsorbents?

<p>Activated carbon is one of the 2 most common adsorbents (A)</p> Signup and view all the answers

Why are porous alumina and porous silica gel commonly used as adsorbents in chromatography?

<p>They provide a high surface area for adsorption (A)</p> Signup and view all the answers

What is a key advantage of using porous alumina and porous silica gel in chromatography applications?

<p>They provide good resolution due to their selectivity (B)</p> Signup and view all the answers

Which statement is true about the mobile phase in thin-layer chromatography (TLC)?

<p>The mobile phase is relatively nonpolar. (D)</p> Signup and view all the answers

How do nonpolar analytes interact with the components of a TLC plate?

<p>They interact weakly with the polar silica gel and strongly with the nonpolar mobile phase. (B)</p> Signup and view all the answers

What happens to nonpolar analytes on a TLC plate?

<p>They move higher up the TLC plate. (A)</p> Signup and view all the answers

Which of the following is true about the interaction between analytes and the components of a TLC plate?

<p>Polar analytes interact more strongly with the polar silica gel. (C)</p> Signup and view all the answers

What is the purpose of using a relatively nonpolar mobile phase in TLC?

<p>To increase the separation of nonpolar analytes on the TLC plate. (D)</p> Signup and view all the answers

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