Chromatographic Separations in Pharmaceutical Analytical Chemistry

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Questions and Answers

What is the basis of separation in chromatography?

  • Relative boiling points of the components
  • Relative molecular weights of the components
  • Relative attraction of components to the stationary and mobile phases (correct)
  • Relative concentration of components in the mixture

How is column chromatography different from planar chromatography?

  • Column chromatography uses a flat surface and capillary action, while planar chromatography involves a narrow column and gravity or pressure for mobile phase flow
  • Column chromatography uses a gas mobile phase, while planar chromatography uses a liquid mobile phase
  • Column chromatography involves a narrow column and gravity or pressure for mobile phase flow, while planar chromatography uses a flat surface and capillary action for mobile phase movement (correct)
  • Column chromatography involves a liquid stationary phase, while planar chromatography uses a solid stationary phase

How are chromatographic techniques often named?

  • By listing the type of stationary phase followed by the type of mobile phase
  • By using numerical codes to represent the types of phases
  • By naming them after their inventors
  • By listing the type of mobile phase followed by the type of stationary phase (correct)

1

<p>PMC205 (C)</p> Signup and view all the answers

What are the types of phases involved in chromatographic techniques?

<p>Mobile phase: liquid or gas; Stationary phase: solid or liquid film coated on a solid substrate (A)</p> Signup and view all the answers

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