Pharmaceutical Analytical Chemistry-I Methods Quiz

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Questions and Answers

What is the result of the interaction between acid and base in the formation of water?

  • Oxygen
  • Salt
  • Hydrogen gas
  • Water (correct)

In the context of chemistry, what is represented by the equation Hg(NO3)2 + 2NaCl → HgCl2 + 2 NaNO3?

  • Neutralization reaction
  • Complexation reaction
  • Redox reaction
  • Formation of weakly ionizable salts (correct)

What type of acid is produced when a salt of weak acid reacts with a strong acid?

  • Base
  • Weak acid (correct)
  • Neutral compound
  • Strong acid

Which type of reaction involves the transfer of electrons between reactants?

<p>Redox reaction (B)</p> Signup and view all the answers

What is formed when a salt of weak base reacts with a strong base?

<p>Weak base (B)</p> Signup and view all the answers

What does the equation Ce4+ + Fe2+ → Fe3+ + Ce3+ represent in terms of chemical reactions?

<p>(Redox reaction) (B)</p> Signup and view all the answers

What is the main principle behind volumetric analysis?

<p>Measuring the volume of a solution of known concentration (C)</p> Signup and view all the answers

Which type of reactions does volumetric analysis involve?

<p>Neutralization, formation of weakly ionizable salts, complexation, and electron transfer (C)</p> Signup and view all the answers

What is the purpose of titration in volumetric analysis?

<p>To find the concentration of the sample by reacting it with a standard solution (A)</p> Signup and view all the answers

Which method relies mainly on physico-chemical properties for analysis?

<p>Spectrophotometric analysis (D)</p> Signup and view all the answers

In which type of reaction does a redox reaction fall under volumetric analysis?

<p>Electron transfer reaction (D)</p> Signup and view all the answers

What does a conductometric method of analysis primarily measure?

<p>Electrical conductivity (B)</p> Signup and view all the answers

What does qualitative analysis focus on?

<p>Identification of chemicals through physical examination (D)</p> Signup and view all the answers

Which method of quantitative analysis involves measuring quantities not exceeding 1 mg?

<p>Micro-analysis (D)</p> Signup and view all the answers

What is the primary focus of volumetric analysis?

<p>Measurement of volume of a solution (A)</p> Signup and view all the answers

What distinguishes gravimetric methods of analysis from volumetric methods?

<p>Measurement of weight (A)</p> Signup and view all the answers

In which type of quantitative analysis, the measured quantities range from 10 - 100 mg?

<p>Semi-micro-analysis (B)</p> Signup and view all the answers

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Study Notes

Analytical Chemistry

  • Qualitative analysis involves identifying chemicals through physical examination and chemical examination
  • Quantitative analysis deals with determining the concentration of the substance to be analyzed

Classification of Quantitative Analysis

  • According to the quantity measured:
    • Macro-analysis: quantities starting from 100 mg and more
    • Semi-micro-analysis: quantities ranging from 10-100 mg
    • Micro-analysis: quantities not exceeding 1 mg
  • According to the physical state of the substance: methods may be classified according to the kind of analyzed material (e.g., food analysis and water analysis)
  • According to the process of measurement:
    • Volumetric methods
    • Gravimetric methods
    • Instrumental methods

Volumetric Analysis

  • Involves measuring the volume of a solution of known concentration (standard solution) to determine the concentration of the analyte (sample)
  • Also known as titration, which is the capacity of the sample to combine with the suitable standard quantitatively through a quantitative reaction
  • Quantitative reactions involve:
    • Weakly ionizable compounds
    • Weak acid, weak base, sparingly soluble salts (precipitate), complex ion, and weak oxidant and reductant

Types of Volumetric Analysis

  • Neutralization reaction:
    • Formation of water (e.g., H+ + OH- → H2O)
    • Displacement titration:
      • Formation of weakly ionizable acid (e.g., KCN + HCl → HCN + KCl)
      • Formation of weakly ionizable base (e.g., NH4Cl + NaOH → NH4OH + NaCl)
  • Formation of weakly ionizable salts:
    • Reaction between a highly ionizable mercuric salt and chloride ion (e.g., Hg(NO3)2 + 2NaCl → HgCl2 + 2NaNO3)
  • Complexation reactions:
    • Formation of inner complex or chelate (e.g., Ca2+ + H2Y2- → CaY2- + 2H+)
  • Electron transfer reactions (Redox reactions):
    • Transfer of electrons between reactants followed by a change in oxidation number (e.g., Ce4+ + Fe2+ → Fe3+ + Ce3+)

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