COPY: Chapter 20 pharm
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Questions and Answers

Which of the following describes the toxic effect of cholinergic drugs?

  • Relaxation of the bladder sphincter
  • Increased heart rate, vasodilation, and bronchiole constriction
  • Salivation, lacrimation, urinary incontinence, diarrhea, GI cramps, and emesis (correct)
  • Treatment of vertigo, memory loss, and tinnitus
  • Which cholinergic drug is used to treat excessively dry mouth?

  • Cevimeline (correct)
  • Succinylcholine
  • Neostigmine
  • Echothiopate
  • What is the antidote to cholinergic drugs?

  • Cevimeline
  • Gingko
  • Atropine (correct)
  • Bethanechol
  • What is the function of cholinergic drugs?

    <p>Decrease heart rate and constrict pupils (A)</p> Signup and view all the answers

    What does the SLUDGE acronym stand for in the context of cholinergic drugs?

    <p>Salivation, lacrimation, urinary incontinence, diarrhea, GI cramps, and emesis (C)</p> Signup and view all the answers

    Which drug is used to relax the sphincter in the bladder, allowing it to empty?

    <p>Bethanechol (D)</p> Signup and view all the answers

    What is the primary function of Ginkgo according to the text?

    <p>Memory enhancement (B)</p> Signup and view all the answers

    What are the effects of cholinergic drugs on the cardiovascular system?

    <p>Decrease heart rate, vasodilate, and constrict bronchioles (D)</p> Signup and view all the answers

    Which drug serves as an antidote for a severe overdose of tricyclic antidepressants?

    <p>Neostigmine (D)</p> Signup and view all the answers

    What interactions may Ginkgo have with other medications?

    <p>Anticoagulants, NSAIDs, and Anticonvulsants (B)</p> Signup and view all the answers

    Which drug is used for glaucoma and intraocular surgery?

    <p>All answers are correct (C)</p> Signup and view all the answers

    What effect do cholinergic drugs have on the body?

    <p>Increased sweating and urination (C)</p> Signup and view all the answers

    Which of the following is a potential use for atropine?

    <p>Counteracting the effects of cholinergic drugs (C)</p> Signup and view all the answers

    What is the role of succinylcholine in general anesthesia?

    <p>Blocking neuromuscular activity (C)</p> Signup and view all the answers

    Cholinergic drugs effect pupils, intestines, bladder, salivation glands, and sweat glands.

    <p>True (A)</p> Signup and view all the answers

    Study Notes

    Cholinergic Drugs

    • Cholinergic drugs can cause toxicity resulting in excessive salivation, lacrimation, urination, diarrhea, gastrointestinal distress, and muscle twitching.
    • Pilocarpine is the cholinergic drug used to treat excessively dry mouth, known as xerostomia.
    • Atropine serves as the antidote to cholinergic drug toxicity and overdoses.
    • Cholinergic drugs primarily function to enhance the action of the neurotransmitter acetylcholine, promoting increased stimulation of the parasympathetic nervous system.

    SLUDGE Acronym

    • SLUDGE stands for Salivation, Lacrimation, Urination, Diarrhea, Gastrointestinal distress, and Emesis, indicating the side effects caused by cholinergic stimulation.

    Bladder Sphincter Relaxation

    • Bethanechol is the drug used to relax the sphincter in the bladder, facilitating urination.

    Ginkgo Biloba

    • Ginkgo is primarily known for enhancing cognitive function and improving blood circulation in the brain.

    Cardiovascular Effects

    • Cholinergic drugs lead to bradycardia (reduced heart rate), decreased cardiac output, and hypotension due to their action on the cardiovascular system.

    Tricyclic Antidepressant Antidote

    • Sodium bicarbonate is often used as the antidote for severe overdose cases of tricyclic antidepressants.

    Ginkgo Interactions

    • Ginkgo may interact with anticoagulants, antiplatelet medications, and certain antidepressants, potentially increasing the risk of bleeding.

    Glaucoma Treatment

    • Pilocarpine is also the drug used for the treatment of glaucoma and during intraocular surgical procedures.

    General Effects of Cholinergic Drugs

    • Cholinergic drugs stimulate various bodily systems, leading to effects such as miosis (pupil constriction), increased intestinal motility, enhanced bladder contraction, and stimulation of salivary and sweat glands.

    Atropine Uses

    • Potential uses for atropine include treating bradycardia and as a pre-anesthetic agent to reduce salivation.

    Succinylcholine Role

    • Succinylcholine is utilized in general anesthesia to induce muscle relaxation and facilitate intubation by temporarily paralyzing skeletal muscles.

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    Test your knowledge about cholinergic drugs, their effects on various body systems, toxic effects, and the antidote to cholinergic drugs. Explore indications for cholinergic drugs and their impact on bodily functions.

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