Cholinergic Agonists Chapter 4 Quiz
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Questions and Answers

Which type of Cholinomimetic Drugs inhibits acetylcholinesterase?

  • Direct-acting Nicotinic Agonists
  • Direct-acting Muscarinic Alkaloids
  • Endogenous Choline Esters (correct)
  • Direct-acting Cholinergic Agonists

What is the main effect of Acetylcholine on the heart rate and cardiac output?

  • Increase heart rate and cardiac output
  • No effect on heart rate and cardiac output
  • Decrease heart rate and cardiac output (correct)
  • Maintain heart rate and cardiac output

Which drug is primarily used topically for the treatment of glaucoma?

  • Cevimeline
  • Carbachol (correct)
  • Betanechol
  • Pilocarpine

What is the main clinical use of Pilocarpine?

<p>Glaucoma (C)</p> Signup and view all the answers

Which drug is commonly used for smoking cessation?

<p>Nicotine (D)</p> Signup and view all the answers

What is the main mechanism of action of indirect-acting Cholinomimetics?

<p>Inhibition of acetylcholinesterase (C)</p> Signup and view all the answers

What type of drugs mimic the actions of acetylcholine?

<p>Cholinergic Agonists (D)</p> Signup and view all the answers

Which neurotransmitter acts on preganglionic fibers, autonomic ganglia, and postganglionic fibers of the parasympathetic division?

<p>Acetylcholine (B)</p> Signup and view all the answers

What is the specific effect on the heart caused by muscarinic receptor activation?

<p>Negative chronotropy and inotropy (D)</p> Signup and view all the answers

Which receptor subtype is found in the neuromuscular junctions?

<p>NM receptor (C)</p> Signup and view all the answers

What are the parasympathetic effects that can result from cholinergic activation?

<p>Bradycardia and bronchoconstriction (C)</p> Signup and view all the answers

Which organ experiences an increase in motility and stimulation of secretion due to direct-acting cholinoceptor drugs?

<p>GI tract (D)</p> Signup and view all the answers

Which drug is an irreversible cholinesterase inhibitor?

<p>Soman (B)</p> Signup and view all the answers

What is the clinical use of Echothiophate?

<p>Glaucoma (B)</p> Signup and view all the answers

Which drug is used for the treatment of mild to moderate Alzheimer's disease?

<p>Galantamine (D)</p> Signup and view all the answers

What is the antidote for organophosphate poisoning?

<p>Atropine (B)</p> Signup and view all the answers

Which drug is obsolete and was used in the treatment of glaucoma?

<p>Echothiophate (D)</p> Signup and view all the answers

What autoimmune disease affects skeletal muscle neuromuscular junctions?

<p>Myasthenia gravis (B)</p> Signup and view all the answers

'Tensilon' is the brand name for which short-acting cholinesterase inhibitor?

<p>Edrophonium (A)</p> Signup and view all the answers

'Mestinon' is the brand name for which intermediate-acting cholinesterase inhibitor?

<p>Pyridostigmine (A)</p> Signup and view all the answers

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