Cholinergic Agonists Chapter 4 Quiz
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Cholinergic Agonists Chapter 4 Quiz

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Questions and Answers

Which type of Cholinomimetic Drugs inhibits acetylcholinesterase?

  • Direct-acting Nicotinic Agonists
  • Direct-acting Muscarinic Alkaloids
  • Endogenous Choline Esters (correct)
  • Direct-acting Cholinergic Agonists

    • What is the main effect of Acetylcholine on the heart rate and cardiac output?

  • Increase heart rate and cardiac output
  • No effect on heart rate and cardiac output
  • Decrease heart rate and cardiac output (correct)
  • Maintain heart rate and cardiac output

    • Which drug is primarily used topically for the treatment of glaucoma?

  • Cevimeline
  • Carbachol (correct)
  • Betanechol
  • Pilocarpine

    • What is the main clinical use of Pilocarpine?

    <p>Glaucoma</p> Signup and view all the answers

    Which drug is commonly used for smoking cessation?

    <p>Nicotine</p> Signup and view all the answers

    What is the main mechanism of action of indirect-acting Cholinomimetics?

    <p>Inhibition of acetylcholinesterase</p> Signup and view all the answers

    What type of drugs mimic the actions of acetylcholine?

    <p>Cholinergic Agonists</p> Signup and view all the answers

    Which neurotransmitter acts on preganglionic fibers, autonomic ganglia, and postganglionic fibers of the parasympathetic division?

    <p>Acetylcholine</p> Signup and view all the answers

    What is the specific effect on the heart caused by muscarinic receptor activation?

    <p>Negative chronotropy and inotropy</p> Signup and view all the answers

    Which receptor subtype is found in the neuromuscular junctions?

    <p>NM receptor</p> Signup and view all the answers

    What are the parasympathetic effects that can result from cholinergic activation?

    <p>Bradycardia and bronchoconstriction</p> Signup and view all the answers

    Which organ experiences an increase in motility and stimulation of secretion due to direct-acting cholinoceptor drugs?

    <p>GI tract</p> Signup and view all the answers

    Which drug is an irreversible cholinesterase inhibitor?

    <p>Soman</p> Signup and view all the answers

    What is the clinical use of Echothiophate?

    <p>Glaucoma</p> Signup and view all the answers

    Which drug is used for the treatment of mild to moderate Alzheimer's disease?

    <p>Galantamine</p> Signup and view all the answers

    What is the antidote for organophosphate poisoning?

    <p>Atropine</p> Signup and view all the answers

    Which drug is obsolete and was used in the treatment of glaucoma?

    <p>Echothiophate</p> Signup and view all the answers

    What autoimmune disease affects skeletal muscle neuromuscular junctions?

    <p>Myasthenia gravis</p> Signup and view all the answers

    'Tensilon' is the brand name for which short-acting cholinesterase inhibitor?

    <p>Edrophonium</p> Signup and view all the answers

    'Mestinon' is the brand name for which intermediate-acting cholinesterase inhibitor?

    <p>Pyridostigmine</p> Signup and view all the answers

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