Podcast
Questions and Answers
Which type of glycosphingolipid is negatively charged at physiologic pH due to the presence of N-acetylneuraminic acid?
Which type of glycosphingolipid is negatively charged at physiologic pH due to the presence of N-acetylneuraminic acid?
- Ceramide
- Cerebrosides
- Gangliosides (correct)
- Sulfatides
In which tissue are gangliosides primarily found?
In which tissue are gangliosides primarily found?
- Kidney
- Nerve tissue (correct)
- Myelin sheath
- Peripheral nervous tissue
What is the role of sulfatides in cerebrosides?
What is the role of sulfatides in cerebrosides?
- Found predominantly in the brain
- Negatively charged at physiologic pH
- Primary synthesis in Golgi apparatus
- Contain sulfated galactosyl residues (correct)
Which compound serves primarily as an intermediate in the synthesis and degradation of glycosphingolipids?
Which compound serves primarily as an intermediate in the synthesis and degradation of glycosphingolipids?
What provides the negative charge in acidic glycosphingolipids at physiologic pH?
What provides the negative charge in acidic glycosphingolipids at physiologic pH?
Which type of fatty acid is attached to the sphingosine in glycosphingolipids found predominantly in the brain?
Which type of fatty acid is attached to the sphingosine in glycosphingolipids found predominantly in the brain?
Where are gangliosides derivatives primarily found?
Where are gangliosides derivatives primarily found?
Which part of the nerve cells is rich in gangliosides?
Which part of the nerve cells is rich in gangliosides?
What is the main interest in lipid storage disorders involving glycosphingolipids?
What is the main interest in lipid storage disorders involving glycosphingolipids?
In glycosphingolipids, what provides the negative charge in acidic glycosphingolipids at physiologic pH?
In glycosphingolipids, what provides the negative charge in acidic glycosphingolipids at physiologic pH?
Where does the synthesis of glycosphingolipids primarily occur?
Where does the synthesis of glycosphingolipids primarily occur?
What type of fatty acid is attached to the sphingosine in glycosphingolipids found predominantly in the brain?
What type of fatty acid is attached to the sphingosine in glycosphingolipids found predominantly in the brain?
Which organelle is responsible for the degradation of glycosphingolipids?
Which organelle is responsible for the degradation of glycosphingolipids?
What is the primary function of sulfatides in nerve tissue?
What is the primary function of sulfatides in nerve tissue?
Which part of the nerve cells contains the most complex glycosphingolipids?
Which part of the nerve cells contains the most complex glycosphingolipids?
What differentiates gangliosides from acidic glycosphingolipids?
What differentiates gangliosides from acidic glycosphingolipids?
What is the key role of N-acetylneuraminic acid (NANA) in glycosphingolipids?
What is the key role of N-acetylneuraminic acid (NANA) in glycosphingolipids?
Where is the highest concentration of cerebrosides found in the body?
Where is the highest concentration of cerebrosides found in the body?
