18 Questions
What is the major structural lipid in the membranes of nerve tissue?
Sphingomyelin
What is the product of sphingomyelin degradation by sphingomyelinase?
Sphingosine
Which enzyme is responsible for degrading sphingomyelin into ceramide?
Sphingomyelinase
What is the role of diacylglycerol in cellular responses?
Activate protein kinase C
Which coenzyme is required for the reaction involving sphingosine-based phospholipids?
Pyridoxal phosphate
What is the major component of skin that regulates water permeability?
Ceramide
What mediates the mobilization of intracellular calcium in response to PIP2 degradation?
Inositol 1,4,5-trisphosphate (IP3)
What is the primary fatty acid found in Sphingomyelin of the myelin sheath?
Lignoceric Acid
What is the primary function of glucocerebroside?
Serving as an intermediate in the synthesis and degradation of glycosphingolipids
What differentiates acidic glycosphingolipids from other types?
They contain sulfate groups or sialic acid for negative charge
Where are gangliosides primarily found?
In ganglion cells of the central nervous system
What makes sulfatides unique among glycosphingolipids?
They contain sulfated galactosyl residues and are negatively charged
Which part of gangliosides contributes to their negative charge?
N-acetylneuraminic acid (NANA)
How do glucosylceramides differ from gangliosides?
They contain N-acetylneuraminic acid (NANA) residues
What is the primary site of synthesis for glycosphingolipids?
Golgi apparatus
What aspect of sulfatides distinguishes them from other cerebrosides?
Sulfated galactosyl residues and negative charge
What is the primary role of gangliosides within nerve cells?
Electrical signal propagation
What sets apart ceramides from sulfatides among cerebrosides?
Sulfate groups give sulfatides a negative charge
Test your knowledge on choline intake requirements, the role of choline in the synthesis of acetylcholine, and the significance of DPPC in lung surfactant production by type II pneumocytes. Learn how DPPC helps reduce surface tension in the alveoli.
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