Cholesterol Biosynthesis

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Questions and Answers

Which enzyme is the rate limiting step in cholesterol synthesis?

  • Acetyl CoA
  • Cytosolic HMG-CoA synthase
  • HMG-CoA reductase (correct)
  • NADPH

What provides the reducing equivalents required for cholesterol synthesis?

  • Cytosolic HMG-CoA synthase
  • HMG-CoA reductase
  • Acetyl CoA
  • NADPH (correct)

What is the final product of cholesterol synthesis?

  • Steroid hormones
  • Vitamin D
  • Bile salts
  • Cholesterol (correct)

Which of the following is NOT a function of cholesterol?

<p>Producing precursors to metabolic processes (C)</p> Signup and view all the answers

What is the major site of cholesterol synthesis in the body?

<p>Liver (C)</p> Signup and view all the answers

Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

<p>HMG-CoA reductase (A)</p> Signup and view all the answers

Which enzyme is responsible for the conversion of HMG-CoA to mevalonate, the rate-limiting step in cholesterol synthesis?

<p>HMG-CoA reductase (D)</p> Signup and view all the answers

What is the major site of cholesterol synthesis in the body?

<p>Liver (D)</p> Signup and view all the answers

Which of the following is NOT a function of cholesterol?

<p>Conductance of an action potential (A)</p> Signup and view all the answers

Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

<p>HMG-CoA reductase (A)</p> Signup and view all the answers

What is the major site of cholesterol synthesis in the body?

<p>Endoplasmic reticulum (ER) (C)</p> Signup and view all the answers

What is the function of ACAT in cholesterol fate?

<p>Stores cholesterol as cholesterol ester (D)</p> Signup and view all the answers

Which of the following is an essential function of cholesterol?

<p>Regulates fluidity of lipid bilayer (A)</p> Signup and view all the answers

What is the major site of cholesterol synthesis in the body?

<p>Liver (A)</p> Signup and view all the answers

Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

<p>HMG-CoA reductase (A)</p> Signup and view all the answers

Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

<p>HMG-CoA reductase (A)</p> Signup and view all the answers

What provides the reducing equivalents required for cholesterol synthesis?

<p>NADPH (B)</p> Signup and view all the answers

What is the major site of cholesterol synthesis in the body?

<p>Endoplasmic reticulum (A)</p> Signup and view all the answers

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