Cholesterol Biosynthesis
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Questions and Answers

Which enzyme is the rate limiting step in cholesterol synthesis?

  • Acetyl CoA
  • Cytosolic HMG-CoA synthase
  • HMG-CoA reductase (correct)
  • NADPH
  • What provides the reducing equivalents required for cholesterol synthesis?

  • Cytosolic HMG-CoA synthase
  • HMG-CoA reductase
  • Acetyl CoA
  • NADPH (correct)
  • What is the final product of cholesterol synthesis?

  • Steroid hormones
  • Vitamin D
  • Bile salts
  • Cholesterol (correct)
  • Which of the following is NOT a function of cholesterol?

    <p>Producing precursors to metabolic processes</p> Signup and view all the answers

    What is the major site of cholesterol synthesis in the body?

    <p>Liver</p> Signup and view all the answers

    Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

    <p>HMG-CoA reductase</p> Signup and view all the answers

    Which enzyme is responsible for the conversion of HMG-CoA to mevalonate, the rate-limiting step in cholesterol synthesis?

    <p>HMG-CoA reductase</p> Signup and view all the answers

    What is the major site of cholesterol synthesis in the body?

    <p>Liver</p> Signup and view all the answers

    Which of the following is NOT a function of cholesterol?

    <p>Conductance of an action potential</p> Signup and view all the answers

    Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

    <p>HMG-CoA reductase</p> Signup and view all the answers

    What is the major site of cholesterol synthesis in the body?

    <p>Endoplasmic reticulum (ER)</p> Signup and view all the answers

    What is the function of ACAT in cholesterol fate?

    <p>Stores cholesterol as cholesterol ester</p> Signup and view all the answers

    Which of the following is an essential function of cholesterol?

    <p>Regulates fluidity of lipid bilayer</p> Signup and view all the answers

    What is the major site of cholesterol synthesis in the body?

    <p>Liver</p> Signup and view all the answers

    Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

    <p>HMG-CoA reductase</p> Signup and view all the answers

    Which enzyme is responsible for the rate-limiting step in cholesterol synthesis?

    <p>HMG-CoA reductase</p> Signup and view all the answers

    What provides the reducing equivalents required for cholesterol synthesis?

    <p>NADPH</p> Signup and view all the answers

    What is the major site of cholesterol synthesis in the body?

    <p>Endoplasmic reticulum</p> Signup and view all the answers

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