CHF Treatment with Vasodilators

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What is the primary reason for discontinuing ACEI 36 hours prior to starting Sacubitril/valsartan therapy?

To prevent hypertension

To minimize the risk of angioedema

To ensure the efficacy of Sacubitril/valsartan

To reduce the risk of adverse interactions (correct)

What is the benefit of using ARNI in heart failure patients?

Reduces mortality and hospitalization (correct)

Increases cardiac output

Improves renal function

Reduces blood pressure

What is the primary goal of using Digoxin in heart failure patients?

To reduce blood pressure

To increase cardiac output

To reduce the risk of arrhythmias

To improve symptoms and reduce hospitalization (correct)

Why is it necessary to monitor serum Digoxin levels closely?

Due to its narrow therapeutic index Signup and view all the answers

What increases the risk of Digoxin toxicity?

All of the above Signup and view all the answers

What is the antidote for Digoxin toxicity?

DigiBind Signup and view all the answers

What is the primary mechanism by which angiotensin converting enzyme inhibitors (ACEI) reduce cardiac work and increase cardiac output?

By interrupting the conversion of angiotensin I to angiotensin II Signup and view all the answers

What is the primary benefit of using angiotensin receptor neprilysin inhibitor (ARNI) in chronic heart failure?

Decreasing mortality rates and preventing cardiac complications Signup and view all the answers

What is the primary goal of pharmacotherapy in chronic heart failure?

To reduce cardiac work and increase cardiac output Signup and view all the answers

What is the primary effect of vasoconstriction on the heart in chronic heart failure?

It increases afterload and ventricular wall stress Signup and view all the answers

What is the primary benefit of using beta blockers in chronic heart failure?

To decrease mortality rates and hospital admissions Signup and view all the answers

What is the primary management strategy for chronic heart failure?

To reduce cardiac work and increase cardiac output Signup and view all the answers

What is the benefit of vasodilators in patients with CHF?

Reduces myocardial work by reducing peripheral vascular resistance and afterload Signup and view all the answers

What is the class I indication for vasodilators in patients with HFrEF?

NYHA class III or IV, self-described as African American Signup and view all the answers

What is the benefit of loop diuretics in patients with CHF?

Relieves symptoms of heart failure Signup and view all the answers

What is the benefit of spironolactone in patients with NYHA class II-IV with an LVEF of 35% or less?

Reduces morbidity and mortality Signup and view all the answers

What is the effect of digitalis glycosides/cardiac glycosides on the heart?

Increases the strength of myocardial contraction Signup and view all the answers

What is the benefit of ACE inhibitors and β-blockers in patients with HFrEF?