120 Questions
Which category of drugs is used to help neutralize gastric acid and reduce symptoms of indigestion and heartburn?
Antacids
What is the purpose of antiemetic drugs?
To prevent and treat nausea and vomiting
What do cytoprotective drugs do?
Protect the lining of the stomach and prevent further damage from stomach acid
Which drugs reduce nausea and vomiting by binding to cannabinoid receptors and preventing serotonin from binding to its receptors?
Cannabinoids
Which part of the digestive system does not have the mucous protection that the stomach has?
Duodenum
What is the function of prostaglandins in the digestive system?
Maintaining good blood flow to the stomach
What are the direct-acting stimuli that can cause nausea and vomiting?
Motion sickness and fear
What can happen if patients with nausea and vomiting are not properly monitored and managed?
Dehydration and weight loss
Which vital signs should be assessed before giving any antiemetic agent?
Heart rate and blood pressure
What should be done if a patient vomits after taking an antiemetic drug?
Record the color, consistency, and amount of the vomit
What should be done if a patient experiences severe abdominal pain after taking an antiemetic drug?
Report the symptoms to the healthcare provider immediately
Why should patients taking antiemetic drugs avoid driving or using heavy machinery?
Because the drugs can cause dizziness and drowsiness
Which of the following is a common side effect of serotonin (5-HT3) receptor antagonists?
Dizziness
What is the recommended dosage range for dronabinol (Marinol, Syndros) as liquid-filled capsules?
5 mg/m2 orally
What is the initial dose of nabilone (Cesamet) given before chemotherapy?
1–2 mg
Which of the following drugs increases contraction of the upper GI tract by blocking dopamine (D2) receptors in the CTZ and the intestinal tract?
Metoclopramide (Reglan)
Which class of antiemetic drugs reduces or halts nausea and vomiting by blocking serotonin (5-HT3) receptors in the intestinal tract and the CTZ?
Serotonin (5-HT3) receptor antagonists
Which neurotransmitter causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Serotonin
What is the major use of serotonin (5-HT3) receptor antagonists?
To reduce or prevent the nausea and vomiting resulting from cancer chemotherapy, radiation therapy, and anesthesia-induced nausea and vomiting after surgery
Which class of antiemetic drugs reduces or prevents immediate and delayed nausea and vomiting by blocking substance P/neurokinin1 receptors in the CTZ?
Substance P antagonists
Which class of drugs reduces gastric acid secretions by inhibiting the binding of histamine to H2 receptors on the parietal cells in the stomach?
Histamine H2-receptor antagonists
Which class of drugs promotes bowel movements by stimulating peristalsis, increasing the bulk of the stool, or by softening the stool?
Laxatives
Which class of drugs reduces GI motility and increases the ability of the intestine to absorb water?
Opioid agonists
Which class of drugs increases contraction of the upper GI tract, including the stomach and the small intestines, to move contents more quickly through the tract?
Promotility drugs
Which of the following is a common use for drugs in the class of substance P/NK1 receptor antagonists?
To manage delayed nausea and vomiting after chemotherapy
Which of the following is an expected side effect of substance P/NK1 receptor antagonists?
Fatigue
Which of the following is an adverse reaction associated with substance P/NK1 receptor antagonists?
Neutropenia
Which of the following drug interactions should be used with caution when taking substance P/NK1 receptor antagonists?
Benzodiazepines
Which of the following is NOT a side effect of substance P/NK1 receptor antagonists?
Thrombocytopenia
Which of the following should be consulted for more information about specific drugs in the class of substance P/NK1 receptor antagonists?
A drug reference book
Which category of drugs is used to prevent and treat nausea and vomiting?
Antiemetic drugs
What is the purpose of cytoprotective drugs?
To protect the lining of the stomach
Which class of drugs reduces or stops loose, watery stools and helps restore normal bowel movements?
Antidiarrheals
What is the major use of cannabinoids?
To reduce nausea and vomiting
Which of the following is a common side effect of substance P/NK1 receptor antagonists?
Dizziness and drowsiness
What is the initial dose of nabilone (Cesamet) given before chemotherapy?
5 mg
Which neurotransmitter causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Serotonin
What should be done if a patient vomits after taking an antiemetic drug?
Monitor the patient's vital signs
Which class of drugs reduces gastric acid secretions by inhibiting the binding of histamine to H2 receptors on the parietal cells in the stomach?
Histamine H2-receptor antagonists
What is the major use of serotonin (5-HT3) receptor antagonists?
To reduce or halt nausea and vomiting
Which class of drugs increases contraction of the upper GI tract, including the stomach and the small intestines, to move contents more quickly through the tract?
Promotility drugs
Which neurotransmitter causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Substance P
Which class of antiemetic drugs reduces or halts nausea and vomiting by blocking dopamine (D2) receptors in the CTZ?
Phenothiazines
Which class of antiemetic drugs reduces or prevents immediate and delayed nausea and vomiting by blocking substance P/neurokinin1 receptors in the CTZ?
Substance P antagonists
Which class of antiemetic drugs promotes bowel movements by stimulating peristalsis, increasing the bulk of the stool, or by softening the stool?
Promotility drugs
Which class of antiemetic drugs reduces or halts nausea and vomiting by blocking serotonin (5-HT3) receptors in the intestinal tract and the CTZ?
Serotonin (5-HT3) receptor antagonists
Which of the following is a serious adverse effect of antiemetic drugs?
Parkinson's disease-like tremors
Which of the following drugs is typically reserved for patients who do not respond to other categories of antiemetics?
Dronabinol
What is the initial dose of dronabinol (Marinol, Syndros) given before chemotherapy?
5 mg/m2 as liquid-filled capsules
Which class of drugs increases contraction of the upper GI tract by blocking dopamine (D2) receptors in the CTZ and the intestinal tract?
Promotility drugs
Which class of drugs is used to prevent and treat nausea and vomiting that occur with any problem?
Serotonin receptor antagonists
Which class of antiemetic drugs reduces or prevents immediate and delayed nausea and vomiting by blocking substance P/neurokinin1 receptors in the CTZ?
Substance P antagonists
Which class of drugs increases contraction of the upper GI tract by blocking dopamine (D2) receptors in the CTZ and the intestinal tract?
Phenothiazines
Which class of antiemetic drugs reduces or halts nausea and vomiting by blocking serotonin (5-HT3) receptors in the intestinal tract and the CTZ?
Serotonin receptor antagonists
Which of the following is the most common use for drugs in the class of substance P/NK1 receptor antagonists?
To reduce or prevent nausea and vomiting from cancer chemotherapy
What is one of the expected side effects of substance P/NK1 receptor antagonists?
Diarrhea
Which of the following is one of the adverse reactions associated with substance P/NK1 receptor antagonists?
Neutropenia
Which of the following drug interactions should be used with caution when taking substance P/NK1 receptor antagonists?
Benzodiazepines
What is the purpose of using substance P/NK1 receptor antagonists in combination with serotonin (5-HT3) receptor antagonists?
To enhance the antiemetic effect
Which of the following is NOT a common side effect of substance P/NK1 receptor antagonists?
Hiccups
Which class of antiemetic drugs reduces or halts nausea and vomiting by blocking dopamine (D2) receptors in the CTZ and the intestinal tract?
Phenothiazines
What is one of the expected side effects of substance P/NK1 receptor antagonists?
Constipation
Which of the following is a common use for drugs in the class of substance P/NK1 receptor antagonists?
Managing nausea and vomiting
What is the major use of cannabinoids?
Managing nausea and vomiting
Which neurotransmitter causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Serotonin
What is the major use of substance P/neurokinin1 (NK1) receptor antagonists?
To prevent and treat nausea and vomiting
What should be done if a patient experiences severe abdominal pain after taking an antiemetic drug?
Stop taking the drug and report the symptoms to the healthcare provider
What is the purpose of antiemetic drugs?
To prevent and treat nausea and vomiting
Which class of drugs protects the lining of the stomach and prevents further damage to the lining from stomach acid?
Cytoprotective drugs
What is the major use of serotonin (5-HT3) receptor antagonists?
To prevent and treat nausea and vomiting
Which class of drugs reduces or prevents immediate and delayed nausea and vomiting by blocking substance P/neurokinin1 receptors in the CTZ?
Substance P/NK1 receptor antagonists
Which class of antiemetic drugs reduces or halts nausea and vomiting by blocking dopamine (D2) receptors in the CTZ and the intestinal tract?
Promotility drugs
Which class of drugs inhibits the binding of histamine to H2 receptors on the parietal cells in the stomach, thereby decreasing gastric acid secretions?
Histamine H2-receptor antagonists
What is the major use of proton pump inhibitors?
To reduce symptoms of indigestion and heartburn
Which class of drugs reduces nausea and vomiting by blocking dopamine receptors in the CTZ?
Phenothiazine
Which class of drugs increases contraction of the upper GI tract, including the stomach and the small intestines, to move contents more quickly through the tract?
Promotility drugs
Which class of antiemetic drugs reduces or prevents immediate and delayed nausea and vomiting by blocking substance P/neurokinin1 receptors in the CTZ?
Serotonin (5-HT3) receptor antagonists
What is the recommended dosage range for ondansetron (Zofran, Zuplenz) given 30 minutes before chemotherapy?
8 mg
Which neurotransmitter causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Serotonin
What is the purpose of phenothiazines as antiemetic drugs?
To reduce or prevent immediate and delayed nausea and vomiting
Which of the following drugs is typically reserved for patients who do not respond to other categories of antiemetics?
Dronabinol
What is the recommended dosage range for dronabinol (Marinol, Syndros) as liquid-filled capsules?
5 mg/m2
What is the initial dose of nabilone (Cesamet) given before chemotherapy?
1-2 mg
Which class of drugs increases contraction of the upper GI tract by blocking dopamine (D2) receptors in the CTZ and the intestinal tract?
Promotility drugs
Which of the following is one of the expected side effects of substance P/NK1 receptor antagonists?
Muscle weakness and fatigue
What is one of the most common adverse reactions associated with substance P/NK1 receptor antagonists?
Neutropenia
Which class of drugs do substance P/NK1 receptor antagonists interact with, causing increased dizziness, drowsiness, and sedation?
Opioid drugs
What is the major use of serotonin (5-HT3) receptor antagonists?
To reduce or prevent nausea and vomiting from cancer chemotherapy and after surgery
What is the purpose of antiemetic drugs?
To reduce or prevent nausea and vomiting
What is the most common use for drugs in the class of substance P/NK1 receptor antagonists?
To reduce or prevent nausea and vomiting from cancer chemotherapy and after surgery
Which category of drugs is used to help neutralize gastric acid and reduce symptoms of indigestion and heartburn?
Antacids
Which category of drugs is used to prevent and treat nausea and vomiting?
Antiemetic drugs
Which category of drugs protects the lining of the stomach and prevents further damage from stomach acid?
Cytoprotective drugs
Which category of drugs reduces or stops loose, watery stools (diarrhea) and helps restore normal bowel movements?
Antidiarrheals
Which receptors in the CTZ can cause nausea and vomiting when activated?
Substance P/NK1 receptors
Which neurotransmitter is released from cells exposed to chemotherapy and tissues injured during surgery that can bind to and trigger the CTZ?
Substance P
Which class of antiemetic drugs blocks the substance P/NK1 receptors in the CTZ?
Substance P/NK1 receptor antagonists
What is the major use of substance P/NK1 receptor antagonists?
To reduce or prevent immediate and delayed nausea and vomiting
Which class of antiemetic drugs reduces or halts nausea and vomiting by blocking dopamine (D2) receptors in the CTZ and the intestinal tract?
Promotility drugs
What is the recommended dosage range for dronabinol (Marinol, Syndros) as liquid-filled capsules?
5 mg/m2 orally
Which neurotransmitter causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Serotonin
Which class of drugs inhibits the binding of histamine to H2 receptors on the parietal cells in the stomach, thereby decreasing gastric acid secretions?
H2 receptor antagonists
Which class of drugs reduces or halts nausea and vomiting by blocking serotonin (5-HT3) receptors in the intestinal tract and the CTZ?
Serotonin (5-HT3) receptor antagonists
What is the major neurotransmitter that causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Serotonin
Which class of antiemetic drugs reduces or prevents immediate and delayed nausea and vomiting by blocking substance P/neurokinin1 receptors in the CTZ?
Substance P/neurokinin1 receptor antagonists
Which class of drugs reduces nausea and vomiting by blocking dopamine (D2) receptors in the CTZ?
Phenothiazines
Which class of antiemetic drugs is used to prevent and treat nausea and vomiting that occur with any problem?
Cannabinoids
Which neurotransmitter causes nausea and vomiting when it binds to its receptors in either the CTZ or the GI system?
Serotonin
What is the major use of phenothiazines as antiemetic drugs?
Increasing contraction of the upper GI tract by blocking dopamine (D2) receptors in the CTZ and the intestinal tract
What is the purpose of antiemetic drugs?
To prevent and treat nausea and vomiting that occur with any problem
Which class of drugs promotes bowel movements by stimulating peristalsis, increasing the bulk of the stool, or by softening the stool?
Opioid agonists
What is the major use of proton pump inhibitors?
To block acid secretion into the stomach by binding to the proton pump of the parietal cells
Which class of drugs reduces or halts nausea and vomiting by blocking dopamine receptors in the CTZ?
Phenothiazine
What is the major use of serotonin (5-HT3) receptor antagonists?
To reduce or halt nausea and vomiting by blocking (5-HT3) receptors in the intestinal tract and the CTZ
Which class of drugs is most effective at managing delayed nausea and vomiting that often starts 24 to 72 hours after chemotherapy?
Substance P/NK1 receptor antagonists
What is one of the adverse reactions associated with substance P/NK1 receptor antagonists?
Neutropenia
What are the expected side effects of substance P/NK1 receptor antagonists?
Fatigue, diarrhea, headache, and dizziness
Which class of drugs do substance P/NK1 receptor antagonists interact with, causing increased dizziness, drowsiness, and sedation?
Opioid drugs
What is the major use of substance P/NK1 receptor antagonists?
To reduce or prevent nausea and vomiting from cancer chemotherapy and after surgery
What are some of the nursing implications for substance P/NK1 receptor antagonists?
All of the above
Protocols and Monitoring in Chemotherapy Administration Test your knowledge of the importance of following protocols and monitoring vital signs during chemotherapy administration. Learn how to identify potential complications such as abdominal pain and nausea, and ensure patient safety throughout the treatment process.
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