Chemistry: Bio-organic and Medicinal Chemistry Unit-III

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18 Questions

Which functional groups play a significant role in the structure-activity relationships of drug molecules?

-OH group and -NH2 group

What is the classification of amino acids based on their zwitter ion structure?

Neutral, acidic, basic

Which method is used to determine the N-terminal amino acid of a peptide?

Edman method

Which structure of proteins involves the arrangement of multiple folded polypeptide chains?

Quaternary structure

What is the mechanism of enzyme action primarily based on?

Lock-and-key or induced fit model

In enzyme inhibition, what type of inhibition occurs when the inhibitor binds to a site other than the active site?

Allosteric inhibition

What is the mechanism that explains the conversion between alpha and beta forms of glucose?

Lobry de Bruyn- van Ekenstein rearrangement

Which of the following is a reducing sugar?

Fructose

What is the type of bond that links monosaccharides to form disaccharides?

Glycosidic bond

Which of the following is not a constituent of nucleic acids?

Uracyl

What is the primary function of DNA and RNA in biological systems?

Genetic information storage and transmission

In drug discovery, what does the Retrosynthetic approach primarily involve?

Starting with the target compound and working backwards to simpler molecules

Which law states that the interfacial angles in crystals remain constant?

Law of constancy of interfacial angles

What is the primary focus of Laue's method in determining crystal structures?

Crystal structure determination

Which type of polymers are characterized by being cross-linked or networked?

Cross-linked polymers

What is the primary bonding force in polymers known as?

Secondary bond force

Which method is used to determine the Weight Average Molecular Mass (Mw) of polymers?

Gel permeation chromatography

What is the primary focus of Ziegler-Natta polymerization?

Chain-growth polymerization

Explore the syllabus for Unit-III: Chemistry of Carbohydrates, covering topics like classification, properties, structures, and interconversions of glucose and fructose. Learn about reducing and non-reducing sugars, epimers, mutarotation, anomers, and Fischer's proof of configuration.

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