Chapters on Hyperlipoproteinemia and Lipid Drugs

<p>Colesevelam (D)</p> Signup and view all the answers

<p>Hyperlipidemia Combinate (A)</p> Signup and view all the answers

<p>Reduction de LDL plasmatic (A)</p> Signup and view all the answers

<p>Debilitate muscular (A)</p> Signup and view all the answers

<p>Maladia hepatic active (B)</p> Signup and view all the answers

<p>Inhibition selective del absorption intestinal de cholesterol dietari e phytosterol (C)</p> Signup and view all the answers

<p>Quando le beneficios excede le risco potential al feto (D)</p> Signup and view all the answers

<p>Graviditate (A)</p> Signup and view all the answers

<p>Inhibir le lipolyse in texitos peripheric (B)</p> Signup and view all the answers

<p>Rubor cutanee e prurito (B)</p> Signup and view all the answers

<p>Augmenta le numero de receptores LDL disponibile per inhibir PCSK9 que normalmente se liga a illos. (C)</p> Signup and view all the answers

<p>Reducir le nivellos de LDL (D)</p> Signup and view all the answers

<p>Reduction in LDL e un augmento moderate in HDL (C)</p> Signup and view all the answers

<p>Pro que le biosynthese de cholesterol occurre principalmente de nocte (A)</p> Signup and view all the answers

<p>Simvastatina (C)</p> Signup and view all the answers

<p>Reactiones al sito de injection (D)</p> Signup and view all the answers

<p>Stimular le oxidation de acidos grasse via PPAR-α. (D)</p> Signup and view all the answers

<p>Hypercholesterolemia familial (C)</p> Signup and view all the answers

<p>Diabete Mellitus (A)</p> Signup and view all the answers

<p>Pro que es essential pro le disveloppamento del feto/infante (C)</p> Signup and view all the answers

<p>Il ha datos de securitate limitate e potential risco de damno al feto. (C)</p> Signup and view all the answers

<p>Cholelithiasis (calculos in le vesicula biliari). (A)</p> Signup and view all the answers

<p>Activation de PPARα pro reducer le synthese hepatic e secretion de VLDL. (A)</p> Signup and view all the answers

<p>Hypertriglyceridemia sever. (D)</p> Signup and view all the answers

<p>Insufficientia renal. (C)</p> Signup and view all the answers

<p>Augmentar le nivellos de HDL per 10-25%. (B)</p> Signup and view all the answers

<p>Illos ha monstrate effectos embryocidal e teratogenic in animales experimental. (C)</p> Signup and view all the answers

<p>Le fibratos de secunde generation reduce le LDL plasmatic plus efficacemente. (D)</p> Signup and view all the answers

<p>Resinas, acido nicotinic, e statins (A)</p> Signup and view all the answers

<p>Reduction marcate de LDL (A)</p> Signup and view all the answers

<p>Quando statins solmente es insufficiente. (C)</p> Signup and view all the answers

<p>Niacina (C)</p> Signup and view all the answers

<p>Niacina (D)</p> Signup and view all the answers

<p>Cholestyramina (D)</p> Signup and view all the answers

<p>Augmentation de activitate de lipoproteina lipasa (B)</p> Signup and view all the answers

<p>Maximisar le effectos additive durante que diminui le risiko de effectos adverse (C)</p> Signup and view all the answers

A condition characterized by very high levels of chylomicrons, triglycerides (TG), and cholesterol.

A class of drugs, known as statins, used to lower LDL cholesterol levels.

A disorder associated with increased levels of VLDL and IDL, leading to high cholesterol levels.

A group of drugs that primarily lower triglycerides and improve HDL cholesterol levels.

A genetic disorder that causes very high levels of LDL cholesterol.

Conditions where a drug should not be used, e.g., in pregnancy or nursing.

An enzyme involved in cholesterol synthesis, crucial during pregnancy.

Certain medications can increase the risk of side effects when taken together.

Most statins should be taken in the evening for effectiveness.

Inactive prodrugs that become active in the liver after metabolism.

A vitamin that lowers LDL and triglycerides; taken orally.

Common side effects include flushing, gastrointestinal upset, and hepatotoxicity.

Used to treat hypercholesterolemia, hypertriglyceridemia, and hyperlipidemia.

Inhibits intestinal absorption of dietary cholesterol and phytosterols.

Reduces Plasma TC and LDL, increases HDL minimally.

Low incidence of hepatic impairment, muscle weakness, pancreatitis.

Used for hypercholesterolemia, phytosterolemia, and in children with familial hypercholesterolemia.

Un substancia que impedi un processu chimic.

Recettor activator pro oxidazione de acidos grasos.

Niveles elevatos de trigliceridos en sangu.

Forma de calculos biliaires in vesicula biliare.

An enzyme that binds to LDL receptors to prevent LDL removal from blood.

Drugs that increase LDL receptor availability, reducing LDL levels in the blood.

PCSK9 inhibitors lower plasma LDL by 50-60%.

Used in familial hypercholesterolemia, CVD with high LDL, and statin intolerance.

Common side effects include injection site reactions, flu-like symptoms, and headaches.

Drugs that reduce cholesterol production in the liver.

A drug used when statins alone are insufficient for LDL reduction.

A resin that lowers LDL cholesterol with minimal toxicity.

A medication that decreases cholesterol absorption in the intestines.

Flushing and itchiness relieved by aspirin after taking niacin.

A drug that increases lipoprotein lipase activity to lower triglycerides.

Using multiple agents like statins and PCSK9i to lower LDL further.