9 Questions
What is the term for the shape of the active site being modified by the binding of the substrate?
Induced fit
Which factor is important for lowering the activation energy in catalysis?
Binding energy
In enzyme-substrate interactions, when does maximal binding energy release occur?
During transition state formation
What happens to the transition state in an enzyme-catalyzed reaction?
It is unstable
What defines whether the transition state will convert into substrate or product?
Energy difference (ΔG) between substrates and products
Which type of interactions contribute to the free energy released when substrate binds to an enzyme?
Weak interactions
What principle does the binding energy between enzyme and substrate help to satisfy in catalysis?
Principle of specificity
What type of selection occurs when a substrate only binds to enzymes with specific active site conformations?
Conformational selection
What term describes the free energy released upon binding of a substrate to an enzyme?
Binding energy
Explore the role of enzymes in accelerating reactions and their specificity in binding specific substrates and producing specific products. Learn how proteolytic enzymes like papain catalyze proteolysis by cleaving peptide bonds.
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