Podcast
Questions and Answers
Who is Karl Lashley?
Who is Karl Lashley?
He began the search for the engram.
What is an engram?
What is an engram?
The hypothetical physical unit of storage of a memory.
What did Karl Lashley suspect?
What did Karl Lashley suspect?
That there might be cells or groups of cells that transform when information has been acquired.
What did Karl Lashley find?
What did Karl Lashley find?
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What did Addis et al. show?
What did Addis et al. show?
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What do Quiroga's studies suggest?
What do Quiroga's studies suggest?
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What is Alzheimer's disease?
What is Alzheimer's disease?
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Memory deficits are also a common symptom of what?
Memory deficits are also a common symptom of what?
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What's the biggest source of TBIs?
What's the biggest source of TBIs?
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What is clinical psychology?
What is clinical psychology?
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What are neurons?
What are neurons?
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What do neurons allow us to do?
What do neurons allow us to do?
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What does the nucleus of the neuron house?
What does the nucleus of the neuron house?
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What surrounds the nucleus?
What surrounds the nucleus?
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What does the soma contain?
What does the soma contain?
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What do the fibers do?
What do the fibers do?
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What are the two types of fibers?
What are the two types of fibers?
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What is the dendrite?
What is the dendrite?
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What is the axon?
What is the axon?
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What is an action potential?
What is an action potential?
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The axon of one neuron does not actually touch the dendrite of the next neuron.
The axon of one neuron does not actually touch the dendrite of the next neuron.
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What is the synapse?
What is the synapse?
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The transfer of information between neurons occurs chemically, rather than electrically.
The transfer of information between neurons occurs chemically, rather than electrically.
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What are terminal buttons?
What are terminal buttons?
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What happens when the electrical signal reaches the terminal buttons?
What happens when the electrical signal reaches the terminal buttons?
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How is the flow of information in the neurons?
How is the flow of information in the neurons?
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What type of dendrites experience a greater loss of electrical power?
What type of dendrites experience a greater loss of electrical power?
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How is the transmission of information in the axon?
How is the transmission of information in the axon?
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How fast does information flow in the axon?
How fast does information flow in the axon?
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What is multiple sclerosis?
What is multiple sclerosis?
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What is the loss of movement and coordination in multiple sclerosis due to?
What is the loss of movement and coordination in multiple sclerosis due to?
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What specialized neurons do sensory systems have?
What specialized neurons do sensory systems have?
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What are neurotransmitters?
What are neurotransmitters?
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How do you classify neurotransmitters?
How do you classify neurotransmitters?
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What is the most commonly found neurotransmitter in the brain?
What is the most commonly found neurotransmitter in the brain?
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What kind of neurons use Acetylcholine?
What kind of neurons use Acetylcholine?
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What makes Parkinson's Disease happen?
What makes Parkinson's Disease happen?
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What is the substantia nigra?
What is the substantia nigra?
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What are some symptoms of Parkinson's disease?
What are some symptoms of Parkinson's disease?
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How does ecstasy (MDMA) affect the brain?
How does ecstasy (MDMA) affect the brain?
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What does cocaine do?
What does cocaine do?
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What does Lysergic acid diethylamide (LSD) do?
What does Lysergic acid diethylamide (LSD) do?
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What does caffeine affect?
What does caffeine affect?
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What does nicotine do?
What does nicotine do?
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What is the left hemisphere focused on?
What is the left hemisphere focused on?
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What is the right hemisphere heavily involved in?
What is the right hemisphere heavily involved in?
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What are subcortical structures?
What are subcortical structures?
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What is the thin top layer of the brain and what is it associated with?
What is the thin top layer of the brain and what is it associated with?
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What are the types of subcortical structures related to memory?
What are the types of subcortical structures related to memory?
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What is the hippocampus?
What is the hippocampus?
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What is the hippocampus a part of?
What is the hippocampus a part of?
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Where is the limbic system/ hippocampus located?
Where is the limbic system/ hippocampus located?
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How is the hippocampus?
How is the hippocampus?
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Damage to the hippocampus can cause what?
Damage to the hippocampus can cause what?
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What does data show in regards to the hippocampus?
What does data show in regards to the hippocampus?
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What is the amygdala and where is it?
What is the amygdala and where is it?
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What is the amygdala highly connected to?
What is the amygdala highly connected to?
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What is the amygdala associated with?
What is the amygdala associated with?
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What part of the brain includes the thalamus and the hypothalamus?
What part of the brain includes the thalamus and the hypothalamus?
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What is the hypothalamus?
What is the hypothalamus?
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What is the thalamus?
What is the thalamus?
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With respect to memory, what does the diencephalon include?
With respect to memory, what does the diencephalon include?
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What is the amnesic syndrome related to damage to the diencephalon?
What is the amnesic syndrome related to damage to the diencephalon?
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What does Korsakoff's disease involve?
What does Korsakoff's disease involve?
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What does the cerebral cortex consist of?
What does the cerebral cortex consist of?
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What are the cognitive function specialties for the frontal lobe?
What are the cognitive function specialties for the frontal lobe?
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What is the prefrontal cortex?
What is the prefrontal cortex?
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What is source monitoring?
What is source monitoring?
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What is the prefrontal lobe also associated with?
What is the prefrontal lobe also associated with?
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What are the cognitive function specialties for the temporal lobe?
What are the cognitive function specialties for the temporal lobe?
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What are the areas of the temporal lobe most involved in memory processing?
What are the areas of the temporal lobe most involved in memory processing?
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What is the medial temporal cortex involved in?
What is the medial temporal cortex involved in?
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What can damage to the medial temporal cortex cause?
What can damage to the medial temporal cortex cause?
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What are the cognitive function specialties for the parietal lobe?
What are the cognitive function specialties for the parietal lobe?
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What are the cognitive function specialties for the occipital lobe?
What are the cognitive function specialties for the occipital lobe?
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What is V4?
What is V4?
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What is neuroimaging?
What is neuroimaging?
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What is the oldest of the neuroimaging techniques?
What is the oldest of the neuroimaging techniques?
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What is EEG technology based on?
What is EEG technology based on?
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The electrical activity of the brain can be measured every?
The electrical activity of the brain can be measured every?
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What is EEG important for?
What is EEG important for?
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What is Intracranial EEG (electrocorticography)?
What is Intracranial EEG (electrocorticography)?
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What are Event-related potentials (ERP)?
What are Event-related potentials (ERP)?
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What is Magnetoencephalography (MEG)?
What is Magnetoencephalography (MEG)?
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What does Positron Emission Tomography (PET) allow?
What does Positron Emission Tomography (PET) allow?
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What can have potentially negative effects during a PET?
What can have potentially negative effects during a PET?
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What is PET useful for?
What is PET useful for?
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What does PET now allow for?
What does PET now allow for?
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What is white matter (MRI)?
What is white matter (MRI)?
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What is grey matter (MRI)?
What is grey matter (MRI)?
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What is MRI commonly used for?
What is MRI commonly used for?
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What is diffusion tensor imaging (DTI)?
What is diffusion tensor imaging (DTI)?
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What is DTI useful for?
What is DTI useful for?
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What is Transcranial Magnetic Stimulation (TMS)?
What is Transcranial Magnetic Stimulation (TMS)?
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One can infer what from TMS?
One can infer what from TMS?
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What is Transcranial Direct Current Stimulation (DSC)?
What is Transcranial Direct Current Stimulation (DSC)?
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What are the medical applications for DSC?
What are the medical applications for DSC?
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What is Deep Brain Stimulation (DBS)?
What is Deep Brain Stimulation (DBS)?
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What is DBS useful for?
What is DBS useful for?
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What is Anterograde Amnesia?
What is Anterograde Amnesia?
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Study Notes
Memory and the Brain
- Karl Lashley initiated "The search for the engram," exploring how memories are stored in the brain.
- An engram represents a physical unit of memory storage, signifying changes in the brain to retain new information.
- Lashley suspected the existence of specific cells that change when learning occurs, but concluded that memory representation instead arises from interconnections between various brain regions.
- Addis et al. discovered that visual areas activate during autobiographical recall, alongside traditional memory areas like the hippocampus.
- Research by Quiroga indicated potential engrams, as different brain areas activate with recognition of various celebrity names.
Alzheimer's Disease and Brain Injuries
- Alzheimer's disease is a common form of dementia in older adults, with memory loss being the initial symptom.
- Memory deficits are prevalent in individuals with Traumatic Brain Injuries (TBIs), primarily caused by motor vehicle crashes (17%).
- Clinical psychology focuses on aiding recovery for brain-damaged patients.
Neurons and their Functions
- Neurons are specialized biological cells dedicated to information transmission and retention.
- They enable functions like movement, vision, thought, and memory.
- The nucleus of a neuron contains chromosomes that hold DNA, surrounded by the soma or cell body that supports cellular functions.
- Neurons possess fibers that transmit information; they include dendrites (receiving signals) and axons (sending signals).
- Action potentials represent the electrochemical process for information transmission along axons.
- Synapses are the gaps between neurons where neurotransmitters facilitate chemical communication, overcoming the non-contact nature of axon-dendrite connections.
Neurotransmitters and Their Effects
- Neurotransmitters are proteins produced by the nervous system, classified by their ability to induce electric currents in dendrites.
- GABA is the most prevalent neurotransmitter in the brain.
- Acetylcholine is active in muscle control, while dopamine production issues in the substantia nigra lead to Parkinson's disease, characterized by motor difficulties.
- Psychotropic substances like MDMA, cocaine, LSD, caffeine, and nicotine influence mood and brain activity by altering neurotransmitter release.
Brain Hemispheres and Structures
- The left hemisphere is associated with language, whereas the right hemisphere focuses on spatial cognition and music processing.
- The cerebral cortex, the brain's outer layer, handles higher cognitive functions, while subcortical structures like the hippocampus and amygdala play crucial roles in memory functions.
- The hippocampus is essential for learning and memory, forming part of the limbic system located in the medial temporal lobe.
Damage and Memory
- Damage to the hippocampus can cause amnesia, impairing memory functions differently depending on the affected hemisphere.
- The amygdala is involved in emotional learning and fear conditioning, heavily connected to the hippocampus and hypothalamus.
- The diencephalon encompasses the thalamus and hypothalamus, forming vital connections for memory processing.
Neuroimaging Techniques
- Neuroimaging maps brain structures and functions using techniques like EEG, which captures electrical activity, critical for diagnosing sleep and epilepsy.
- PET scans create detailed brain images but entail the use of a radioactive substance, suitable for isolating functional brain areas.
- MRI assesses structural brain damage, while DTI examines white matter connections, assisting in diagnosing conditions like Alzheimer's disease.
Brain Stimulation Techniques
- Transcranial Magnetic Stimulation (TMS) and Transcranial Direct Current Stimulation (tDCS) apply stimuli to change brain function, aiding in cognitive performance after strokes or alleviating depressive symptoms.
- Deep Brain Stimulation (DBS) involves implanted devices sending impulses to manage conditions like Parkinson's disease and major affective disorders.
- Anterograde amnesia refers to the inability to form new memories following brain damage.
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Description
Explore the key concepts of memory and its relation to the brain with these flashcards. Delve into definitions and terminology related to Karl Lashley and the engram, essential for understanding how memories are formed and stored. Perfect for students looking to reinforce their knowledge in neuroscience.