Cerebrum Structure and Functions
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Questions and Answers

Which areas, beyond the gyri, are associated with gray matter in the cerebrum?

  • Cortex only
  • Basal nuclei only
  • Both the cortex and basal nuclei (correct)
  • Only white matter

What is a function of the basal nuclei?

  • Control the endocrine system
  • Regulate memory processing
  • Initiate and terminate movements (correct)
  • Coordinate sensory signals

What is the basal nuclei's role in muscle tone?

  • Enhance muscle contraction
  • Suppress muscle tone
  • Regulate muscle tone (correct)
  • None of the above

How many basal nuclei help in movement regulation?

<p>Three (D)</p> Signup and view all the answers

Which diseases are associated with the basal nuclei?

<p>Parkinson’s and Huntington’s (B)</p> Signup and view all the answers

What are the main types of neurons found in the cortex that release glutamate?

<p>Pyramidal neurons (A)</p> Signup and view all the answers

Which neurotransmitter is generally released by interneurons, causing inhibition?

<p>GABA (C)</p> Signup and view all the answers

Which part of the brain shrinks severely in Alzheimer's disease?

<p>Hippocampus (B)</p> Signup and view all the answers

What is the limbic system often referred to as?

<p>The emotional brain (C)</p> Signup and view all the answers

What happens to the cerebral cortex in Alzheimer's disease?

<p>It shrivels up (B)</p> Signup and view all the answers

Which part of a neuron in the cortex forms multiple branches?

<p>Dendrites (B)</p> Signup and view all the answers

Which brain region is critical to the formation of new memories?

<p>Hippocampus (C)</p> Signup and view all the answers

Which of these is NOT a main region of the limbic system?

<p>Prefrontal cortex (C)</p> Signup and view all the answers

What are the two main divisions of the nervous system?

<p>Central nervous system and peripheral nervous system (A)</p> Signup and view all the answers

What does the central nervous system consist of?

<p>Brain and spinal cord (B)</p> Signup and view all the answers

Which division of the nervous system controls involuntary functions such as smooth muscle action, cardiac muscle, and gland activities?

<p>Autonomic nervous system (A)</p> Signup and view all the answers

What is the specific association of the frontal lobes in the human brain?

<p>Higher (executive) functions (D)</p> Signup and view all the answers

Which system is found in the gastrointestinal tract and regulates smooth muscle, glands, and endocrine cells?

<p>Enteric nervous system (A)</p> Signup and view all the answers

Approximately how much brain tissue does the human body use to process all emotions, solve equations, and perform other functions?

<p>~3 lbs. (B)</p> Signup and view all the answers

What do the basal nuclei control?

<p>Subconscious contractions of skeletal muscles (B)</p> Signup and view all the answers

Where are the basal nuclei located?

<p>Deep within the brain, at the base of the forebrain (C)</p> Signup and view all the answers

Which of the following is an example of a function of the basal nuclei?

<p>Automatic arm swings while walking (C)</p> Signup and view all the answers

Which brain structure is not listed in the diagram?

<p>Fourth ventricle (B)</p> Signup and view all the answers

What is the basal nuclei's role in response to a joke?

<p>True laughter (A)</p> Signup and view all the answers

Where is the limbic system located within the brain?

<p>Encircling the upper part of the brain stem and the corpus callosum (B)</p> Signup and view all the answers

Which functions are associated with the limbic system?

<p>Emotions, memory, and motivation (B)</p> Signup and view all the answers

Which structures are included in making up the limbic system?

<p>Structures on the inner border of the cerebrum and floor of the diencephalon (D)</p> Signup and view all the answers

What is the main anatomical position of the limbic system?

<p>Deep within the brain (C)</p> Signup and view all the answers

Which description accurately represents the limbic system?

<p>A system of structures responsible for emotions, memory, and motivation (B)</p> Signup and view all the answers

What is cognition?

<p>Mental processes that include memory, producing and understanding language, solving problems, and making decisions (C)</p> Signup and view all the answers

What results from Alzheimer's Disease (AD)?

<p>Dementia (A)</p> Signup and view all the answers

Where does neuronal death occur in Alzheimer's Disease?

<p>The hippocampus and the basal forebrain (C)</p> Signup and view all the answers

What significant change is observed in the brain at the end stage of Alzheimer's Disease?

<p>Dramatic shrinkage (C)</p> Signup and view all the answers

What is currently known about the cure and therapy for Alzheimer's Disease?

<p>It is always fatal (C)</p> Signup and view all the answers

Which pathological feature of Alzheimer’s disease involves the extracellular accumulation of β-amyloid protein?

<p>Extracellular amyloid plaques (C)</p> Signup and view all the answers

Which of the following is NOT a current therapeutic strategy for Alzheimer’s disease?

<p>Surgical resection of affected cortex (C)</p> Signup and view all the answers

What is the role of GABA in antiepileptic drug therapy?

<p>Enhancing GABA-mediated synaptic inhibition (B)</p> Signup and view all the answers

What differentiates partial epilepsy from generalized epilepsy?

<p>Abnormal sensation or aura (B)</p> Signup and view all the answers

Which antiepileptic drug mechanism is particularly important for controlling absence seizures?

<p>Inhibiting T-type calcium channels (D)</p> Signup and view all the answers

What condition is associated with the repeated occurrence of seizures?

<p>Epilepsy (D)</p> Signup and view all the answers

Which of the following drugs is NOT typically used to treat epilepsy?

<p>Donepezil (B)</p> Signup and view all the answers

What type of brain slices show amyloid plaques in the provided image descriptions?

<p>TG-6 months (B)</p> Signup and view all the answers

Which part of the brain is responsible for relaying most sensory information to the cerebral cortex?

<p>Thalamus (D)</p> Signup and view all the answers

What function does the hypothalamus control?

<p>Homeostatic functions like body temperature and respiration (D)</p> Signup and view all the answers

Which part of the brain contributes to muscle tone, posture, and balance?

<p>Cerebellum (A)</p> Signup and view all the answers

Where is the primary visual area located?

<p>At the posterior tip of the occipital lobe (A)</p> Signup and view all the answers

What does the cerebral cortex enable us to do?

<p>Read, write, speak, remember, and plan our life (B)</p> Signup and view all the answers

What are the folds in the cortex called?

<p>Gyri (A)</p> Signup and view all the answers

Which part of the brain is responsible for regulating heartbeat and breathing?

<p>Brain stem (B)</p> Signup and view all the answers

Which area is the primary gustatory area located in?

<p>Just inferior to the primary somatosensory area (B)</p> Signup and view all the answers

Which of the following is a positive symptom of schizophrenia?

<p>Delusions (D)</p> Signup and view all the answers

What are antipsychotic drugs primarily known as?

<p>Neuroleptic drugs (C)</p> Signup and view all the answers

Which neurotransmitter receptor do antipsychotic drugs predominantly antagonize?

<p>Dopamine (C)</p> Signup and view all the answers

Which drug is used as a thrombolytic in stroke management?

<p>Alteplase (C)</p> Signup and view all the answers

Cognitive deficits in schizophrenia are primarily mediated by which brain structure?

<p>Dorsolateral prefrontal cortex (DLPFC) (B)</p> Signup and view all the answers

Which of the following is a negative symptom of schizophrenia?

<p>Reduced expression of emotion (B)</p> Signup and view all the answers

Which of the following treatments is used for hypertension in stroke management?

<p>Thiazide diuretic (A)</p> Signup and view all the answers

Which of the following neurotransmitters is NOT implicated in the pathophysiology of schizophrenia?

<p>Serotonin (D)</p> Signup and view all the answers

Flashcards

What is the cerebrum?

The cerebrum is the largest part of the brain, responsible for higher-level functions such as thinking, memory, and language.

What is the cerebral cortex?

The cerebral cortex is the outer layer of the cerebrum, composed of gray matter.

What are the basal nuclei?

The basal nuclei are a group of structures located deep within the cerebrum that help regulate movement.

What is Parkinson's disease?

Parkinson's disease is a neurodegenerative disorder that affects the basal nuclei, leading to tremors, stiffness, and impaired movement.

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What is Huntington's disease?

Huntington's disease is a neurodegenerative disorder that affects the basal nuclei, leading to uncontrolled movements, cognitive decline, and behavioral changes.

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What is the limbic system?

The limbic system is a group of brain structures involved in emotions, memory, and motivation.

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What is the amygdala?

The amygdala is part of the limbic system and plays a role in processing fear and other emotions.

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What is the hippocampus?

The hippocampus is part of the limbic system and is crucial for forming new memories.

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What is the cingulate gyrus?

The cingulate gyrus is part of the limbic system and is involved in emotional processing and learning.

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What is the fornix?

The fornix is a pathway that connects the hippocampus to other parts of the brain.

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What is Alzheimer's disease?

Alzheimer's disease is a neurodegenerative disorder that causes progressive memory loss, thinking, and behavior problems.

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Where does neuronal death occur in Alzheimer's disease?

Neuronal death in Alzheimer's disease occurs primarily in the hippocampus and basal forebrain.

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What is the central nervous system (CNS)?

The central nervous system (CNS) consists of the brain and spinal cord.

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What is the peripheral nervous system (PNS)?

The peripheral nervous system (PNS) consists of all the nerves that extend outside the CNS.

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What is the autonomic nervous system (ANS)?

The autonomic nervous system (ANS) controls involuntary functions like heart rate, digestion, and breathing.

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What is the sympathetic division of the ANS?

The sympathetic division of the ANS prepares the body for 'fight or flight' responses.

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What is the parasympathetic division of the ANS?

The parasympathetic division of the ANS promotes 'rest and digest' functions.

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What makes the human brain so complex?

The human brain is incredibly complex, containing billions of neurons and trillions of glial cells.

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What are the frontal lobes associated with?

The frontal lobe is often associated with higher executive functions such as planning, decision-making, and personality.

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What is the longitudinal fissure?

The longitudinal fissure is a deep groove that divides the cerebrum into two hemispheres.

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What is the septum pellucidum?

The septum pellucidum is a thin membrane that separates the lateral ventricles of the brain.

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What is the internal capsule?

The internal capsule is a white matter tract that connects the cerebral cortex to the brainstem.

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What are pyramidal neurons and what do they release?

Pyramidal neurons are the main type of neuron found in the cerebral cortex and release glutamate, an excitatory neurotransmitter.

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What are interneurons and what do they release?

Interneurons release GABA, an inhibitory neurotransmitter, and are involved in regulating neuronal activity in the cortex.

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How do pyramidal neurons and interneurons interact?

Networks of pyramidal neurons and interneurons interact to fine-tune cortical function and regulate brain activity.

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How is the limbic system connected to other brain regions?

The limbic system is connected to various brain regions, including the hypothalamus, thalamus, and brainstem, contributing to its role in cognition and emotion.

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What does the brain diagram show?

The diagram illustrates the complex structure of the brain, highlighting key regions and their interconnectivity.

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Study Notes

The Cerebrum

  • The cerebrum consists of the cortex, basal nuclei, and other structures
  • The basal nuclei help initiate and terminate movements, suppress unwanted movements, and regulate muscle tone
  • Diseases associated with the basal nuclei include Parkinson's disease and Huntington's disease

Histology of the Cerebrum

  • The cerebral cortex is composed of cell bodies in layers or sheets
  • The main type of neuron found in the cortex is the pyramidal neuron, which releases glutamate and causes excitation
  • Interneurons, found in the cortex, release GABA and cause inhibition
  • Networks of pyramidal neurons and interneurons are fine-tuned to regulate cortical function

The Limbic System

  • The limbic system is a functional system composed of parts of the cerebral cortex, diencephalon, and midbrain
  • The main regions of the limbic system include the amygdala, hippocampus, cingulate gyrus, and fornix
  • The limbic system plays a primary role in emotions, including pleasure, pain, docility, affection, fear, and anger
  • The limbic system also functions in memory, along with parts of the cerebrum

Alzheimer's Disease (AD)

  • AD is a neurodegenerative disease characterized by neuronal death, resulting in dementia
  • Neuronal death occurs in specific brain regions, including the hippocampus and basal forebrain
  • At the end stage, the brain shows dramatic shrinkage
  • There is no known cure or successful therapy, and AD is always fatal
  • Cognitive symptoms of AD include memory loss, language impairment, problem-solving difficulties, and decision-making difficulties

Functional Anatomy of the Brain

  • The nervous system has two divisions: central (CNS) and peripheral (PNS)
  • The CNS consists of the brain and spinal cord, while the PNS consists of all nervous tissue outside the CNS
  • The autonomic nervous system (ANS) has sympathetic and parasympathetic divisions, controlling involuntary functions

The Human Brain

  • The human brain uses approximately 3 lbs of tissue to process emotions, solve equations, read, and breathe
  • The brain is composed of 100 billion neurons and 10 trillion neuroglia
  • The cerebral cortex is the most expanded part of the brain, with the frontal lobes being particularly associated with higher executive functions

The Limbic System (cont.)

  • The limbic system is a collection of brain structures responsible for emotions, memory, and motivation
  • The limbic system is connected to various brain regions and is involved in cognitive and emotional processes

Brain Diagram

  • The diagram shows a cross-section of the brain, highlighting various brain structures, including the longitudinal fissure, septum pellucidum, internal capsule, and basal nuclei

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Description

This quiz covers the structure and functions of the cerebrum, including the basal nuclei, cortex, and their roles in movement and muscle tone. It also touches on related diseases such as Parkinson's and Huntington's.

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