Cerebrovascular Accidents and Neurological Disorders

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Questions and Answers

Which of the following is a clinical manifestation of COPD?

  • Edema
  • Mental deterioration
  • Liver enlargement
  • Chronic cough (correct)

What is the primary cause of emphysema in COPD patients?

  • Excessive mucus production
  • Pulmonary hypertension
  • Inflammation of the bronchi
  • Loss of lung elasticity due to alveoli hyperinflation (correct)

Which risk factor is considered a modifiable risk factor for COPD?

  • Age
  • Immunosuppression
  • Conditions with mucus
  • Smoking (correct)

What causes portal hypertension in cirrhosis?

<p>Obstructed blood flow through the liver (D)</p> Signup and view all the answers

What is a common complication of cirrhosis related to ammonia metabolism?

<p>Hepatic encephalopathy (B)</p> Signup and view all the answers

Which diagnostic test is used specifically to diagnose COPD?

<p>Pulmonary function test (A)</p> Signup and view all the answers

What leads to the production of excessive mucus in chronic bronchitis?

<p>Hypertrophy of bronchial walls (C)</p> Signup and view all the answers

What is a consequence of scar tissue replacing healthy liver tissue in cirrhosis?

<p>Reduced hepatic function (C)</p> Signup and view all the answers

What is a common clinical manifestation of esophageal varices?

<p>Hematemesis (D)</p> Signup and view all the answers

Which of the following best describes the pathology of Crohn’s disease?

<p>Transmural skip lesions causing deep ulcerations (B)</p> Signup and view all the answers

What dietary recommendation is often provided for patients with diverticulosis?

<p>Increase dietary fiber from raw fruits and veggies (D)</p> Signup and view all the answers

Which of the following symptoms is typically associated with diverticulitis?

<p>Abdominal pain over sigmoid colon (D)</p> Signup and view all the answers

What effect does Crohn’s disease have on the intestines over time?

<p>Development of fibrotic scarring leading to reduced absorption (C)</p> Signup and view all the answers

Which symptom is NOT typically associated with myasthenia gravis?

<p>Abdominal pain (D)</p> Signup and view all the answers

What is the primary cause of esophageal varices in patients with cirrhosis?

<p>Portal hypertension (B)</p> Signup and view all the answers

What is a potential complication if esophageal varices rupture?

<p>Risk of aspiration and infection (D)</p> Signup and view all the answers

What is primarily responsible for the obstruction of blood flow in peripheral arterial disease (PAD)?

<p>A combination of atherosclerosis, inflammation, stenosis, embolus, and thrombus (B)</p> Signup and view all the answers

Which clinical manifestation is considered a priority for monitoring in patients with peripheral arterial disease?

<p>Intermittent claudication during exercise (D)</p> Signup and view all the answers

Which of the following best describes Virchow's triad related to deep vein thrombosis (DVT)?

<p>Stasis, vessel wall injury, and hypercoagulability (C)</p> Signup and view all the answers

Which symptom is a result of left-sided heart failure?

<p>Pulmonary congestion and crackles (D)</p> Signup and view all the answers

For a patient diagnosed with heart failure, which dietary recommendation is most appropriate?

<p>Low sodium intake (D)</p> Signup and view all the answers

What is a common clinical manifestation of deep vein thrombosis (DVT)?

<p>Pain, swelling, and warmth in the affected area (D)</p> Signup and view all the answers

Which diagnostic test is not typically used for assessing heart failure?

<p>Fasting lipid profile (C)</p> Signup and view all the answers

Which classification indicates significant limitation and distress during physical activity in heart failure patients?

<p>Class IV (C)</p> Signup and view all the answers

What is a common clinical manifestation of ulcerative colitis?

<p>Loss of fluid through diarrhea with more than 20 stools per day (D)</p> Signup and view all the answers

What is the primary underlying cause of cholecystitis?

<p>Obstruction of bile flow due to gallstones (D)</p> Signup and view all the answers

Which bacteria is most commonly associated with cholecystitis?

<p>E.coli (A)</p> Signup and view all the answers

Which of the following is a systemic manifestation of rheumatoid arthritis?

<p>Weight loss (B)</p> Signup and view all the answers

What pathological process occurs in the joints of patients with rheumatoid arthritis?

<p>Chronic autoimmune inflammation and tissue degeneration (D)</p> Signup and view all the answers

What diagnostic test is often used to indicate the presence of rheumatoid arthritis?

<p>Presence of rheumatoid factor (C)</p> Signup and view all the answers

What type of edema is characterized by swelling due to excess fluid accumulation in tissues?

<p>Dependent edema (A)</p> Signup and view all the answers

What is a common diagnostic finding in osteomyelitis?

<p>Increased WBC counts (D)</p> Signup and view all the answers

What is the primary pathophysiological change in osteoporosis?

<p>Rate of osteoclasts exceeds osteoblasts (A)</p> Signup and view all the answers

Which clinical manifestation is associated with chronic osteomyelitis?

<p>Nonhealing ulcer (B)</p> Signup and view all the answers

Which neurotransmitter is usually excitatory and affects mood and overall activity?

<p>Norepinephrine (B)</p> Signup and view all the answers

What is a common prevention strategy for osteoporosis?

<p>Calcium and vitamin D supplementation (C)</p> Signup and view all the answers

Which of the following is NOT a consequence of untreated osteomyelitis?

<p>Spinal deformities (A)</p> Signup and view all the answers

What role does calcitonin play in bone health?

<p>Promotes bone formation (A)</p> Signup and view all the answers

What is the normal range for sodium levels in the blood?

<p>135-145 mEq/L (A)</p> Signup and view all the answers

Which condition is signified by easily fractured bones under stress?

<p>Osteoporosis (A)</p> Signup and view all the answers

What is the GFR range for Stage 2 Chronic Kidney Disease (CKD)?

<p>60-89 (D)</p> Signup and view all the answers

Which condition is indicated by a TSH level greater than 4.5?

<p>Hypothyroidism (D)</p> Signup and view all the answers

What is a common clinical manifestation of hyperthyroidism?

<p>Exophthalmos (D)</p> Signup and view all the answers

What lab value would indicate acidosis?

<p>HCO3 less than 22 (C)</p> Signup and view all the answers

Which test is indicative of latent tetany in patients with hypocalcemia?

<p>Chvostek sign (A)</p> Signup and view all the answers

What is the normal range for TSH levels?

<p>0.4-4.5 (C)</p> Signup and view all the answers

Which GFR range categorizes Stage 4 Chronic Kidney Disease (CKD)?

<p>15-29 (C)</p> Signup and view all the answers

What is a possible complication of Graves' disease?

<p>Thyroid storm (B)</p> Signup and view all the answers

Flashcards

COPD Pathophysiology

Progressive airflow limitation due to an abnormal inflammatory lung response to irritants like particles or gases.

Emphysema

Lung tissue damage, loss of elasticity, and over-inflation of air sacs (alveoli) leading to respiratory acidosis.

Chronic Bronchitis

Inflammation of bronchi/bronchioles, increased mucus production, and narrowed airways. Thick mucus obstructs airflow.

COPD Clinical Manifestations

Chronic cough, sputum production, shortness of breath, barrel chest, and clubbing of fingers/toes.

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Cirrhosis Cause

Excessive alcohol use, or other causes, resulting in liver cell death and scarring (fibrosis) thereby damaging liver functionality.

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Hepatic Encephalopathy Early Stage

Mental changes (confusion) and motor disturbances that are early indicators of hepatic problems.

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Portal Hypertension Path

Obstructed blood flow through the liver leading to increased pressure within the portal venous system.

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Cirrhosis clinical findings

Liver enlargement, portal obstruction, ascites, infections, varices, edema, nutritional deficiencies, and possible mental decline.

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Esophageal Varices in Cirrhosis

Swollen veins in the esophagus caused by liver disease (cirrhosis).

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Crohn's Disease Symptoms

Symptoms include: soft/semidigest stool, nutritional issues, electrolyte problems, and right lower quadrant (RLQ) pain.

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Diverticulitis Patho

Inflammation of pouches (diverticula) in the colon, often due to trapped food and bacteria.

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Diverticulosis

Presence of diverticula (pouches) in the colon, but without inflammation.

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Myasthenia Gravis

Autoimmune disease causing muscle weakness, initially affecting eye muscles.

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Ascites, Cirrhosis

Fluid buildup in the abdomen, a complication of cirrhosis.

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Crohn's Disease Patho

Chronic inflammatory condition causing deep ulcerations and 'skip' lesions through the intestinal walls.

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Diverticulitis Symptoms (Older Adults)

In older patients, diverticulitis can cause confusion, falls, and lack of appetite.

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Peripheral Arterial Disease (PAD)

A chronic condition where blood flow through arteries is obstructed, often due to atherosclerosis, inflammation, or clots.

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PAD Symptoms

Reduced blood pressure in ankle, intermittent claudication (leg pain with exercise), and potential for impaired circulation (e.g., blood clots).

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Deep Vein Thrombosis (DVT)

A blood clot in a large vein, often in the leg or pelvis.

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DVT Risk Factors

Virchow's triad (stasis, vessel injury, hypercoagulability) and factors like injury, surgery, prolonged bed rest, pregnancy, age, cancer, and medications.

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Heart Failure (HF)

A condition where the heart can't effectively pump blood, leading either to trouble filling or ejecting blood.

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Heart Failure Clinical Signs

Symptoms related to fluid overload or inadequate tissue perfusion.

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Heart Failure Diagnostics

Include cardiac markers like troponin and CK, electrolyte checks, and tests evaluating liver, kidney, and blood cell function.

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Heart Failure Diet

A low sodium diet to reduce blood volume.

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Normal GFR

A normal glomerular filtration rate (GFR) is typically considered to be 125 mL/min.

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Stage 1 CKD

Stage 1 Chronic Kidney Disease (CKD) is characterized by a GFR less than or equal to 90 mL/min, but there is no kidney damage yet.

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Stage 5 CKD

End-stage Chronic Kidney Disease (CKD), characterized by a GFR less than 15 mL/min. Need dialysis or a kidney transplant.

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Hypothyroidism

Hypothyroidism is a condition where the thyroid gland does not produce enough thyroid hormones, leading to symptoms like fatigue, weight gain, and cold intolerance.

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Hyperthyroidism

Hyperthyroidism is a condition where the thyroid gland produces too much thyroid hormone, leading to symptoms like weight loss, nervousness, and heat intolerance.

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Chvostek's Sign

Chvostek's sign is a twitching of the facial muscles elicited by tapping on the facial nerve, suggestive of hypocalcemia.

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Trousseau's Sign

Trousseau's sign is a carpopedal spasm (hand and foot cramping) induced by blocking blood flow to the arm, suggestive of hypocalcemia.

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Grave's Disease

Grave's disease is an autoimmune condition that causes hyperthyroidism.

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Pathologic Process in Osteomyelitis

Infection, usually due to MRSA, causes inflammation, increased blood vessel formation, and swelling, leading to blood clots and ultimately tissue death.

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Osteomyelitis Complications

If untreated, bone abscesses can form, leading to chronic bone infection.

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Osteoporosis: Bone Breakdown

Bone-destroying cells (osteoclasts) outpace bone-building cells (osteoblasts), leading to weaker bones.

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Clinical Signs of Osteoporosis

Bones fracture easily, especially in the spine, hip, and wrist. Kyphosis (hunchback) and a protruding abdomen can occur.

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Preventing Osteoporosis

Eat a balanced diet rich in calcium and vitamin D, take calcium supplements if needed, and engage in regular weight-bearing exercise.

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Acetylcholine's Role

Usually an excitatory neurotransmitter, it plays a role in parasympathetic actions, like slowing the heart rate.

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Dopamine's Impact

Usually inhibitory in brain areas related to movement and cognition. Affects behavior, attention, emotions, and fine motor skills.

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Norepinephrine: The 'Exciter'

Generally excitatory, involved in the sympathetic nervous system, influencing mood and overall activity.

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Ascites

Fluid buildup in the abdominal cavity, often associated with liver disease. It's a sign of fluid retention and pressure in the portal vein system.

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Ulcerative Colitis

Chronic inflammation of the large intestine, starting from the rectum and spreading upwards. It affects the mucosa and submucosa, causing diarrhea, blood, mucus, pus, and pain in the lower abdomen.

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Cholecystitis

Inflammation of the gallbladder, typically caused by gallstones blocking the flow of bile. This can lead to pain in the upper right abdomen and potential complications like gangrene.

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Hepatomegaly

Enlargement of the liver, often due to underlying liver diseases like cirrhosis or hepatitis.

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Rheumatoid Arthritis

Autoimmune disorder affecting joints, leading to chronic inflammation, pain, stiffness, and eventually damage to cartilage and bone.

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Pannus Formation

Abnormal tissue growth in the joint lining (synovium) that destroys cartilage and bone in rheumatoid arthritis.

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Crypt Abscess

Pus-filled pockets in the intestinal lining, often seen in inflammatory bowel diseases like ulcerative colitis.

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Osteomyelitis

Infection of the bone, usually caused by bacteria. It can lead to inflammation, pain, and even bone damage.

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Study Notes

Cerebrovascular Accidents

  • Ischemic accidents are caused by an obstruction (thrombus or embolism) disrupting blood supply to brain tissue.
  • Embolic events involve clots forming elsewhere and traveling to the brain.
  • Hemorrhagic accidents involve bleeding into brain tissue, ventricles, or subarachnoid space, often due to high blood pressure.
  • Thrombotic accidents involve blood clots forming in arteries supplying blood to the brain, often due to atherosclerosis.
  • Clinical manifestations can include: hemiplegia (paralysis on one side), hemiparesis (weakness on one side), flaccidity (loss of muscle tone), and ataxia (balance and coordination problems).

Multiple Sclerosis

  • Pathophysiology involves a progressive demyelination of the CNS by immune cells.
  • Clinical manifestations can include relapsing and remitting symptoms such as fatigue, weakness, numbness, and coordination difficulties.

Myocardial Infarction

  • Diagnostics include 12-lead EKG, cardiac labs, and troponin/CK levels.
  • Risk factors include non-modifiable factors (male sex, postmenopausal female, heart disease history) and modifiable factors (smoking, high LDL, diabetes, hypertension).

Atherosclerosis

  • Atherosclerosis involves lipid deposits and fibrous tissue buildup within arterial walls.
  • This condition can lead to coronary artery disease (CAD) due to blockages and narrowing of coronary vessels, reducing blood flow to the myocardium, potentially leading to necrosis.

Parkinson's Disease

  • Cardinal clinical manifestations include tremor, rigidity, bradykinesia/akinesia, and postural instability.

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