Cerebral Ischemia and Infarction

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22 Questions

What is the primary role of neuroimaging in stroke?

To exclude other conditions that can mimic stroke

What is transient ischemic attack (TIA) also known as?

Mini stroke

What is the main difference between ischemic and hemorrhagic stroke?

Cause of the stroke

What is an example of a fixed risk factor for stroke?

Age >80 years

How does hypertension increase the risk of ischemic stroke?

By accelerating atherosclerosis of cerebral blood vessels

What is the outcome of ischemic stroke?

Liquefactive necrosis of brain tissue

What is the pathogenesis of ischemic stroke?

Thrombosis or embolism

What is a modifiable risk factor for stroke?

Hyperlipidemia

What percentage of the total body oxygen consumption is used by the brain?

20%

What is the mechanism that helps maintain constant cerebral perfusion despite changes in blood pressure?

Autoregulation

What is the term for a reduction of blood flow to a localized area of the brain?

Focal cerebral ischemia

What type of infarct occurs in the most distal portions of arterial territories in the brain and spinal cord?

Border zone infarct

What is the most common type of infarct?

Embolic infarct

What determines the clinical deficit in cases of ischemic stroke?

Site and size of the infarct

What is the effect of hypertension on cerebral blood vessels?

It leads to formation of minute aneurysms

What is the gross appearance of intracerebral hemorrhage?

A cavity with brown rim

What is the location of amyloid deposits in cerebral amyloid angiopathy (CAA)?

Cerebral cortex and meninges

What is the characteristic of vascular malformations?

Tangled network of worm-like vascular channels

What is the definition of stroke?

An acute onset neurological deficit due to a vascular disease

What is the effect of infarct or hemorrhage on one side of the brain?

It affects the opposite side of the body

What is the essential investigation in a patient with stroke?

MRI scan of the brain

What is the characteristic of global cerebral ischemia?

It involves the entire brain

This quiz covers the concepts of hypoxia, ischemia, and infarction, specifically in the context of the brain's constant need for glucose and oxygen. It also explores the mechanisms of autoregulation and the differences between global and focal cerebral ischemia.

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