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Questions and Answers
Which class of antibiotics covers pseudomonas and contains agents that resist degradation by beta-lactamases?
Which class of antibiotics covers pseudomonas and contains agents that resist degradation by beta-lactamases?
Which cephalosporin covers MRSA infections?
Which cephalosporin covers MRSA infections?
Which antibiotic class is characterized by having excellent coverage against Gram-negative infections including pseudomonas but lacks reliable Gram-positive or anaerobic coverage?
Which antibiotic class is characterized by having excellent coverage against Gram-negative infections including pseudomonas but lacks reliable Gram-positive or anaerobic coverage?
Which antibiotic class inhibits cell wall synthesis by binding the terminal molecule of the peptidoglycan?
Which antibiotic class inhibits cell wall synthesis by binding the terminal molecule of the peptidoglycan?
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Among the following, which antibiotic is used first-line to treat C.difficile infection and MRSA bacteremia?
Among the following, which antibiotic is used first-line to treat C.difficile infection and MRSA bacteremia?
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Which class of antibiotics is known to hydrolyze all ß-lactam antibiotics except aztreonam?
Which class of antibiotics is known to hydrolyze all ß-lactam antibiotics except aztreonam?
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Which antibiotic class is NOT affected by clavulanic acid or tazobactam?
Which antibiotic class is NOT affected by clavulanic acid or tazobactam?
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Which antibiotic class is characterized by being active against Gram positive agents including MRSA but having no anaerobic coverage?
Which antibiotic class is characterized by being active against Gram positive agents including MRSA but having no anaerobic coverage?
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Which antibiotic class has the characteristic of destroying the cell membrane by direct chemical interaction with LPS?
Which antibiotic class has the characteristic of destroying the cell membrane by direct chemical interaction with LPS?
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Which class of antibiotics treats rickettsial infections and is active against both Gram positive and Gram negative organisms?
Which class of antibiotics treats rickettsial infections and is active against both Gram positive and Gram negative organisms?
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Which of the following cell wall inhibitors primarily targets Gram negative organisms?
Which of the following cell wall inhibitors primarily targets Gram negative organisms?
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Which antibiotic is associated with the unique toxicity of encephalitis?
Which antibiotic is associated with the unique toxicity of encephalitis?
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Which class of ß-lactamases requires zinc and can hydrolyze penicillins and carbapenems?
Which class of ß-lactamases requires zinc and can hydrolyze penicillins and carbapenems?
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Which cell wall inhibitor is mainly used topically for wounds and burn injuries?
Which cell wall inhibitor is mainly used topically for wounds and burn injuries?
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Which of the following antibiotics is NOT associated with renal toxicity?
Which of the following antibiotics is NOT associated with renal toxicity?
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What is the general mechanism of action of penicillins?
What is the general mechanism of action of penicillins?
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Which type of infection is NOT reliably covered by penicillin G and V?
Which type of infection is NOT reliably covered by penicillin G and V?
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What is the main difference between oral Penicillin V and intramuscular Penicillin G?
What is the main difference between oral Penicillin V and intramuscular Penicillin G?
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Which antibiotic class includes drugs like Cephalosporins and Monobactam?
Which antibiotic class includes drugs like Cephalosporins and Monobactam?
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What is the primary target of Carbapenems in bacterial cells?
What is the primary target of Carbapenems in bacterial cells?
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Which organism is NOT covered by aminopenicillins?
Which organism is NOT covered by aminopenicillins?
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Why are beta-lactamases a concern in antibiotic resistance?
Why are beta-lactamases a concern in antibiotic resistance?
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Which penicillin-based drug reliably covers streptococcus and staphylococcus infections?
Which penicillin-based drug reliably covers streptococcus and staphylococcus infections?
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What makes the 5th generation cephalosporins unique?
What makes the 5th generation cephalosporins unique?
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Which class of antibiotics includes agents that cover pseudomonas infections?
Which class of antibiotics includes agents that cover pseudomonas infections?
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Which antibiotic class among penicillins, monobactam, cephalosporins, glycopeptides, and carbapenems is characterized by being active against Gram positive infections, including MRSA, but lacks reliable Gram negative or anaerobic coverage?
Which antibiotic class among penicillins, monobactam, cephalosporins, glycopeptides, and carbapenems is characterized by being active against Gram positive infections, including MRSA, but lacks reliable Gram negative or anaerobic coverage?
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Which antibiotic class contains only one agent (Aztreonam) and has excellent coverage against Gram negative infections, including pseudomonas, but lacks reliable Gram positive or anaerobic coverage?
Which antibiotic class contains only one agent (Aztreonam) and has excellent coverage against Gram negative infections, including pseudomonas, but lacks reliable Gram positive or anaerobic coverage?
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Which antibiotic class is known for resisting degradation by beta-lactamases and includes agents that cover pseudomonas, with the exception of one agent (ertapenem)?
Which antibiotic class is known for resisting degradation by beta-lactamases and includes agents that cover pseudomonas, with the exception of one agent (ertapenem)?
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Among the classes of antibiotics discussed, which one inhibits cell wall synthesis by binding the terminal molecule of the peptidoglycan and prevents further elongation of cell wall polymers?
Among the classes of antibiotics discussed, which one inhibits cell wall synthesis by binding the terminal molecule of the peptidoglycan and prevents further elongation of cell wall polymers?
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Which antibiotic class is specifically highlighted as not containing a beta-lactam ring and consequently does not work by inhibiting PBP in bacterial cells?
Which antibiotic class is specifically highlighted as not containing a beta-lactam ring and consequently does not work by inhibiting PBP in bacterial cells?
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Which antibiotic class is known for reliably covering streptococcus and staphylococcus infections, but does NOT cover Gram-negative, anaerobic, or methicillin-resistant staphylococcus aureus (MRSA) infections?
Which antibiotic class is known for reliably covering streptococcus and staphylococcus infections, but does NOT cover Gram-negative, anaerobic, or methicillin-resistant staphylococcus aureus (MRSA) infections?
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Which beta-lactam antibiotic is unique because it has a modification in structure that makes the drug molecule bulky to resist breakdown by enzymes and reliably covers streptococcus and staphylococcus infections?
Which beta-lactam antibiotic is unique because it has a modification in structure that makes the drug molecule bulky to resist breakdown by enzymes and reliably covers streptococcus and staphylococcus infections?
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Among the following antibiotic classes, which one is NOT reliably covered by aminopenicillins when it comes to Pseudomonas infections?
Among the following antibiotic classes, which one is NOT reliably covered by aminopenicillins when it comes to Pseudomonas infections?
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Which antibiotic class contains agents that are mainly used topically for wounds and burn injuries?
Which antibiotic class contains agents that are mainly used topically for wounds and burn injuries?
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Which class of antibiotics contains drugs that cover Pseudomonas infections and resist degradation by beta-lactamases?
Which class of antibiotics contains drugs that cover Pseudomonas infections and resist degradation by beta-lactamases?
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Which antibiotic inhibits pyruvyl-transferase, an enzyme required for cell wall synthesis?
Which antibiotic inhibits pyruvyl-transferase, an enzyme required for cell wall synthesis?
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Which antibiotic class is known for causing seizures by lowering the seizure threshold?
Which antibiotic class is known for causing seizures by lowering the seizure threshold?
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What sets the 5th generation cephalosporins apart from other generations of cephalosporins in terms of their coverage?
What sets the 5th generation cephalosporins apart from other generations of cephalosporins in terms of their coverage?
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Which antibiotic class is mainly used to treat urinary tract infections and is active against Gram-negative organisms?
Which antibiotic class is mainly used to treat urinary tract infections and is active against Gram-negative organisms?
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Which antibiotic class is NOT covered in the text provided?
Which antibiotic class is NOT covered in the text provided?
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Which antibiotic class is known for its activity against both Gram positive and Gram negative organisms, treating rickettsial infections, and includes drugs like Tetracyclines and Aminoglycosides?
Which antibiotic class is known for its activity against both Gram positive and Gram negative organisms, treating rickettsial infections, and includes drugs like Tetracyclines and Aminoglycosides?
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Which antibiotic class is NOT inhibited by clavulanic acid or tazobactam, has no reliable anaerobic coverage, and can hydrolyze all ß-lactam antibiotics except aztreonam?
Which antibiotic class is NOT inhibited by clavulanic acid or tazobactam, has no reliable anaerobic coverage, and can hydrolyze all ß-lactam antibiotics except aztreonam?
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Which antibiotic class includes Daptomycin that penetrates the cell membrane resulting in efflux of K+ from bacterial cell, is only active against Gram positive agents including MRSA, and cannot be used for lung infections?
Which antibiotic class includes Daptomycin that penetrates the cell membrane resulting in efflux of K+ from bacterial cell, is only active against Gram positive agents including MRSA, and cannot be used for lung infections?
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Which antibiotic class contains agents like Polymyxins that have detergent-like activity, destroy the cell membrane by direct chemical interaction with LPS, and are only active against Gram negative agents?
Which antibiotic class contains agents like Polymyxins that have detergent-like activity, destroy the cell membrane by direct chemical interaction with LPS, and are only active against Gram negative agents?
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Which antibiotic class is characterized by inhibiting protein synthesis by targeting either the 30S or 50S ribosomal subunit, and includes antibiotics like Tetracyclines and Aminoglycosides?
Which antibiotic class is characterized by inhibiting protein synthesis by targeting either the 30S or 50S ribosomal subunit, and includes antibiotics like Tetracyclines and Aminoglycosides?
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What is the unique characteristic of Penicillin G administration?
What is the unique characteristic of Penicillin G administration?
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Which type of infection is reliably covered by Penicillin V?
Which type of infection is reliably covered by Penicillin V?
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What is the primary mechanism of action of Monobactam antibiotics?
What is the primary mechanism of action of Monobactam antibiotics?
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Which antibiotic class provides coverage against Gram-negative infections including Pseudomonas but lacks reliable Gram-positive or anaerobic coverage?
Which antibiotic class provides coverage against Gram-negative infections including Pseudomonas but lacks reliable Gram-positive or anaerobic coverage?
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What is the main difference between Penicillins and Cephalosporins?
What is the main difference between Penicillins and Cephalosporins?
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Which antibiotic is primarily associated with the unique toxicity known as 'Gray baby syndrome'?
Which antibiotic is primarily associated with the unique toxicity known as 'Gray baby syndrome'?
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Which antibiotic class includes drugs that are NOT affected by clavulanic acid or tazobactam?
Which antibiotic class includes drugs that are NOT affected by clavulanic acid or tazobactam?
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Which antibiotic class is characterized by having excellent coverage against Gram-negative infections but lacks reliable Gram-positive or anaerobic coverage?
Which antibiotic class is characterized by having excellent coverage against Gram-negative infections but lacks reliable Gram-positive or anaerobic coverage?
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Which cell wall inhibitor is mainly used topically for wounds and burn injuries?
Which cell wall inhibitor is mainly used topically for wounds and burn injuries?
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Which antibiotic class has the characteristic of destroying the cell membrane by direct chemical interaction with lipopolysaccharides (LPS)?
Which antibiotic class has the characteristic of destroying the cell membrane by direct chemical interaction with lipopolysaccharides (LPS)?
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Which antibiotic class is primarily used for the treatment of C.difficile infections?
Which antibiotic class is primarily used for the treatment of C.difficile infections?
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Which antibiotic class is known for its activity against both Gram positive and Gram negative organisms but lacks reliable anaerobic coverage?
Which antibiotic class is known for its activity against both Gram positive and Gram negative organisms but lacks reliable anaerobic coverage?
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Which of the following antibiotic classes primarily targets MRSA and vancomycin-resistant enterococcus infections?
Which of the following antibiotic classes primarily targets MRSA and vancomycin-resistant enterococcus infections?
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Which antibiotic class is characterized by its activity against Gram positive organisms and anaerobes?
Which antibiotic class is characterized by its activity against Gram positive organisms and anaerobes?
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Among the listed antibiotic classes, which one is least commonly used for antibiotic treatment according to the text?
Among the listed antibiotic classes, which one is least commonly used for antibiotic treatment according to the text?
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Which antibiotic class has been associated with a high risk of pseudomembranous colitis?
Which antibiotic class has been associated with a high risk of pseudomembranous colitis?
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Which antibiotic class is NOT typically resistant to degradation by beta-lactamases?
Which antibiotic class is NOT typically resistant to degradation by beta-lactamases?
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Which antibiotic class is characterized by being active against MRSA but lacking reliable coverage against Gram-negative organisms?
Which antibiotic class is characterized by being active against MRSA but lacking reliable coverage against Gram-negative organisms?
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Among Penicillins, Monobactam, Cephalosporins, and Carbapenems, which class is primarily active against Gram-positive organisms such as MRSA and anaerobes?
Among Penicillins, Monobactam, Cephalosporins, and Carbapenems, which class is primarily active against Gram-positive organisms such as MRSA and anaerobes?
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Which antibiotic class is mainly reserved for methicillin-resistant Staphylococcus aureus (MRSA) infections?
Which antibiotic class is mainly reserved for methicillin-resistant Staphylococcus aureus (MRSA) infections?
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Study Notes
Antibiotic Classes
- Cephalosporins that cover MRSA infections include cephalosporin antibiotics.
- The class of antibiotics that covers pseudomonas and resists degradation by beta-lactamases is Monobactam.
- The antibiotic class characterized by excellent coverage against Gram-negative infections, including pseudomonas, but lacking reliable Gram-positive or anaerobic coverage is Monobactam.
Cell Wall Inhibitors
- The antibiotic class that inhibits cell wall synthesis by binding the terminal molecule of the peptidoglycan is beta-lactam antibiotics.
- Carbapenems primarily target the cell wall of Gram-negative bacteria.
Antibiotic Resistance
- Beta-lactamases are a concern in antibiotic resistance because they can hydrolyze beta-lactam antibiotics.
Antibiotic Characteristics
- Aminopenicillins do not reliably cover Pseudomonas infections.
- Penicillin G is not reliably effective against anaerobic infections.
- The unique characteristic of Penicillin G administration is its short half-life.
- Penicillin V reliably covers streptococcus and staphylococcus infections.
- Cephalosporins are active against Gram-positive and Gram-negative organisms.
Specific Antibiotics
- Metronidazole is used to treat C.difficile infections and is associated with a high risk of pseudomembranous colitis.
- Vancomycin is used to treat MRSA bacteremia and is characterized by its activity against Gram-positive organisms and anaerobes.
- Daptomycin is active against Gram-positive agents, including MRSA, and cannot be used for lung infections.
- Polymyxins have detergent-like activity, destroying the cell membrane by direct chemical interaction with lipopolysaccharides (LPS), and are only active against Gram-negative agents.
Topical Antibiotics
- Cell wall inhibitors like Polymyxins are mainly used topically for wounds and burn injuries.
Antibiotic Toxicity
- Chloramphenicol is associated with the unique toxicity known as 'Gray baby syndrome'.
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Description
Test your knowledge on cephalosporins, carbapenems, and monobactams antibiotics. Learn which antibiotics cover pseudomonas, MRSA, contain a beta-lactam ring, resist degradation by beta-lactamases, and are combined with enzyme inhibitors.
