Cellular Transdifferentiation Quiz
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Questions and Answers

What is transdifferentiation?

The switching of tissue lineage and acquisition of a new set of differentiated characteristics.

What does the term transdifferentiation imply about cell commitments during embryogenesis?

It implies that the commitments cells have made to enter into a specific tissue and cell lineage are not irreversible.

What is the term used to describe the dramatic shift in cell phenotype from epithelial to mesenchymal?

Epithelial-mesenchymal transition, or EMT.

Give an example of how the epithelial-mesenchymal transition can impact cancer cells.

<p>At the borders of many carcinomas, epithelial cancer cells often change shape and gene expression programs to take on attributes of nearby stromal cells of mesenchymal origin.</p> Signup and view all the answers

What may often accompany and enable the invasion of carcinoma cells into adjacent normal tissues?

<p>The epithelial-mesenchymal transition (EMT).</p> Signup and view all the answers

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