Cellular Adaptations and Pathology
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Questions and Answers

What is the term for a decrease in cell size, often due to decreased workload or inadequate nutrition?

  • Metaplasia
  • Hypertrophy
  • Hyperplasia
  • Atrophy (correct)

What is the term for a reversible change in cell type, often in response to chronic irritation or inflammation?

  • Hypertrophy
  • Hyperplasia
  • Dysplasia
  • Metaplasia (correct)

What is the term for unprogrammed cell death, often due to injury, infection, or toxins?

  • Autolysis
  • Necrosis (correct)
  • Apoptosis
  • Dysplasia

What is the term for a rapid, self-limiting response to tissue injury or infection?

<p>Acute inflammation (D)</p> Signup and view all the answers

What is the term for the restoration of tissue architecture and function?

<p>Repair (A)</p> Signup and view all the answers

What is the term for a prolonged, persistent response to tissue injury or infection?

<p>Chronic inflammation (B)</p> Signup and view all the answers

Study Notes

Cellular Adaptations

  • Atrophy: decrease in cell size, often due to decreased workload or inadequate nutrition
  • Hypertrophy: increase in cell size, often due to increased workload or hormonal stimulation
  • Hyperplasia: increase in cell number, often due to hormonal stimulation or chronic irritation
  • Metaplasia: reversible change in cell type, often in response to chronic irritation or inflammation
  • Dysplasia: disorderly growth and maturation of cells, often precancerous

Cellular Injury

  • Reversible injury: cell damage that can be repaired, often due to hypoxia, toxins, or infection
    • Characterized by cellular swelling, fatty change, and disruption of cellular organelles
  • Irreversible injury: cell damage that leads to cell death, often due to severe or prolonged injury
    • Characterized by cellular necrosis, apoptosis, or autolysis

Cell Death

  • Necrosis: unprogrammed cell death, often due to injury, infection, or toxins
    • Characterized by cellular swelling, rupture, and inflammation
  • Apoptosis: programmed cell death, often due to genetic regulation or cellular stress
    • Characterized by cellular shrinkage, chromatin condensation, and phagocytosis

Inflammation

  • Acute inflammation: rapid, self-limiting response to tissue injury or infection
    • Characterized by increased blood flow, increased permeability, and white blood cell infiltration
  • Chronic inflammation: prolonged, persistent response to tissue injury or infection
    • Characterized by tissue damage, scarring, and ongoing inflammation

Repair and Regeneration

  • Repair: restoration of tissue architecture and function
    • Characterized by fibrosis, scar formation, and tissue remodeling
  • Regeneration: replacement of damaged tissue with new tissue
    • Characterized by stem cell activation, proliferation, and differentiation

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Test your knowledge of cellular adaptations, injury, death, inflammation, and repair/regeneration processes. Learn about the different types of cellular changes and responses to injury or infection.

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