Cells and Tissues of the Immune System

Study Notes

Understand immunology and biotechnology terminology.
Explore collaboration between adaptive and acquired immune systems in pathogen defense.
Explain molecular mechanisms of humoral and cell-mediated immunity.
Distinguish between passive and active immunization and their relation to immune-mediated diseases.
Learn molecular basis of inflammation and therapeutic approaches to chronic inflammatory diseases.
Grasp concepts of immunotherapies and therapeutic antibodies.
Discuss principles of immunoassays for biomolecule identification and quantification.

Gain insights into immunology and biotechnology applications in pharmacy practice.
Enhance skills and capabilities within the PharmD program.
Establish a foundation for careers in the pharmaceutical industry.

Immunity is derived from the term "immunitas" in Latin, meaning protection from legal prosecution for Roman senators.
Immunology studies immune responses; immunity refers to protection from infectious diseases.
The immune system comprises tissues, cells, and molecules that respond collectively to foreign substances.

The immune system defends against infectious microbes, but it can react to noninfectious foreign substances as well.
Immune responses involve reactions to components of microbes, macromolecules like proteins and polysaccharides, and small chemicals recognized as foreign.

Bee Sting Reaction:
- Bee venom proteins can trigger pain, swelling, and serious allergic reactions in sensitized individuals.
Sulfonamide Allergy:
- Sulfonamide allergy can provoke hypersensitivity reactions classified by the Gel and Coombs system.
- Type 1 IgE-mediated reactions can lead to anaphylaxis, angioedema, and urticaria.
- Maculopapular eruptions are common, typically emerging 1–2 weeks post-exposure to sulfonamide and resolving after withdrawal.