Cell to Cell Communication Basics

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Questions and Answers

What classification of signalling molecules is based on their solubility?

  • Gas molecules
  • Chemical molecules (correct)
  • Biological molecules
  • Electrical molecules

Which of the following is NOT a characteristic used to classify signalling molecules?

  • Solubility
  • Size
  • Charge
  • Origin (correct)

Which property primarily influences the classification of signalling molecules?

  • pH levels
  • Temperature stability
  • Solubility (correct)
  • Molecular weight

What would be an example of a signalling molecule classified based on solubility?

<p>Insulin (B)</p> Signup and view all the answers

In the context of signalling molecules, what aspect does solubility primarily affect?

<p>Distribution in the body (B)</p> Signup and view all the answers

What is the primary mechanism through which one nerve cell communicates with another?

<p>Paracrine signalling (A)</p> Signup and view all the answers

Which type of signalling is characterized by a cell responding to molecules it has produced itself?

<p>Autocrine signalling (D)</p> Signup and view all the answers

In which situation would paracrine signalling primarily occur?

<p>A neuron releases neurotransmitters to nearby muscle cells (C)</p> Signup and view all the answers

Which of the following best differentiates autocrine signalling from paracrine signalling?

<p>Autocrine signalling affects the same cell, whereas paracrine signalling affects nearby cells. (A)</p> Signup and view all the answers

What role do neurotransmitters play in nerve cell communication?

<p>They facilitate paracrine signalling between adjacent nerve cells. (A)</p> Signup and view all the answers

Quo significa 'neurotransmittores' in le contexto del communication neural?

<p>Substantias chimic liberate per impulsos nerveux que affecta communication intra-nerve. (C)</p> Signup and view all the answers

Qual fase del communication neural involve le diffusion de neurotransmittores?

<p>Le transmission de impulso a un alter neurone o fibra muscular. (B)</p> Signup and view all the answers

Qual es le effecto immediate del impulsos nerveux in relation al neurotransmittores?

<p>Illos provocara le liberazione de neurotransmittores in le synapse. (B)</p> Signup and view all the answers

In le communication nerveuse, a quale structura le neurotransmittores puede esser transferite?

<p>A qualquer structura, incluse fibras musculares. (D)</p> Signup and view all the answers

Qual es le consequence del deficit de neurotransmittores in le communication nerveuse?

<p>Deterioro del communication intercellular e impaire de function. (C)</p> Signup and view all the answers

Qual es le significato de PIP2 in relation a phosphatidylinositol?

<p>Un fosfolipido specifico (B)</p> Signup and view all the answers

Qual es le compositores principal de phosphatidylinositol 4,5 biphosphate?

<p>Glicerol e acidos grassos (A)</p> Signup and view all the answers

In qual typologia de signalling cellulaire PIP2 ha un rol crucial?

<p>Signalling de Second Messenger (D)</p> Signup and view all the answers

Qual es le functione principal de phosphatidylinositol 4,5 biphosphate in le cellula?

<p>Actuar como un precursor de messageres secondarios (B)</p> Signup and view all the answers

Qual es le structurale composition de phosphatidylinositol 4,5 biphosphate?

<p>Un glicerol con dos acidos grassos e un grupo inositol (C)</p> Signup and view all the answers

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Study Notes

Cell to Cell Communication

  • Communication between nerve cells can be achieved using paracrine signalling.
  • Autocrine signalling involves a cell responding to a molecule it has produced.
  • Signalling molecules can be categorized based on their solubility (lipophilic vs. hydrophilic).
  • Lipid derivatives (e.g. steroids and eicosanoids) are lipophilic molecules that act as signalling molecules.
  • Based on receptor interactions, signalling molecules can bind to intracellular receptors (inside the cytosol) or surface receptors.
  • Epinephrine utilizes G protein-linked receptors for its signalling activity.
  • Cell-surface receptors are involved in neurotransmitter signalling. Examples include glutamate and GABA (gamma-aminobutyric acid).

Neurotransmitters

  • Chemical substances released at the end of a nerve fibre by the arrival of a nerve impulse.
  • Neurotransmitters diffuse across the synapse or junction and effect the transfer of the impulse to another nerve fibre, a muscle fibre, or some other structure.
  • Small molecule neurotransmitters include:
    • Glutamate: an amino acid
    • GABA (γ-aminobutyric acid): an amino acid, not found in proteins
    • Glycine: an amino acid
  • Purinergic neurotransmitters include:
    • ATP: a nucleotide
    • Adenosine: a nucleoside

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