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Questions and Answers
What is a key difference between prokaryotic and eukaryotic cells?
What is a key difference between prokaryotic and eukaryotic cells?
During which phase of mitosis do the chromosomes align at the cell's equatorial plane?
During which phase of mitosis do the chromosomes align at the cell's equatorial plane?
Which structure is unique to plant cells during cytokinesis?
Which structure is unique to plant cells during cytokinesis?
What describes the composition of a chromosome?
What describes the composition of a chromosome?
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Which of the following correctly describes sister chromatids?
Which of the following correctly describes sister chromatids?
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What type of ribonucleic acid carries the genetic information from DNA to the ribosome?
What type of ribonucleic acid carries the genetic information from DNA to the ribosome?
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Which term describes the haploid number of chromosomes in humans?
Which term describes the haploid number of chromosomes in humans?
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What is the primary outcome of meiosis?
What is the primary outcome of meiosis?
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What is a primary function of the mitochondrion?
What is a primary function of the mitochondrion?
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Which process occurs during Meiosis I and contributes to genetic diversity?
Which process occurs during Meiosis I and contributes to genetic diversity?
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How do gametes differ from somatic cells in terms of chromosome number?
How do gametes differ from somatic cells in terms of chromosome number?
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What does independent assortment during meiosis refer to?
What does independent assortment during meiosis refer to?
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What genetic configuration results from a true-breeding line?
What genetic configuration results from a true-breeding line?
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Which term describes the physical expression of a genetic trait?
Which term describes the physical expression of a genetic trait?
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In a genetic cross of Aa x Aa, what is the probability of obtaining a homozygous recessive offspring?
In a genetic cross of Aa x Aa, what is the probability of obtaining a homozygous recessive offspring?
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What term is used for the chromosomes that are paired during meiosis?
What term is used for the chromosomes that are paired during meiosis?
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What does Mendel's principle of segregation state?
What does Mendel's principle of segregation state?
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How do genes on separate chromosomes exhibit inheritance patterns according to Mendel's laws?
How do genes on separate chromosomes exhibit inheritance patterns according to Mendel's laws?
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Which of the following correctly describes a test cross?
Which of the following correctly describes a test cross?
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What is the expected phenotypic ratio for a monohybrid cross?
What is the expected phenotypic ratio for a monohybrid cross?
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In the context of genetics, what does co-dominance refer to?
In the context of genetics, what does co-dominance refer to?
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What does the addition rule of probability help determine in genetic crosses?
What does the addition rule of probability help determine in genetic crosses?
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What indicates an X-linked trait in genetic inheritance?
What indicates an X-linked trait in genetic inheritance?
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During a genetic cross, how can actual data be used to test a hypothesis?
During a genetic cross, how can actual data be used to test a hypothesis?
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Study Notes
Cell Structure
- Three Domains of Life: Bacteria, Archaea, and Eukarya
- Prokaryotes: Bacteria and Archaea, lack a nucleus and membrane-bound organelles
- Eukaryotes: Eukarya, have a nucleus and membrane-bound organelles
- Similarities between Prokaryotes and Eukaryotes: Both have DNA, ribosomes, cell membranes, and cytoplasm
- Differences between Prokaryotes and Eukaryotes: Eukaryotes have a nucleus, membrane-bound organelles, and linear DNA, prokaryotes have a nucleoid, circular DNA, and lack membrane-bound organelles
- Cell Wall: A rigid outer layer that provides structural support and protection, found in plants, fungi, and bacteria
- Plasma Membrane: A selectively permeable phospholipid bilayer that regulates the passage of molecules in and out of the cell, found in all cell types
- Nucleus: A membrane-bound organelle containing DNA, found in eukaryotes
- Nuclear Envelope: A double membrane surrounding the nucleus, regulates the movement of molecules between the nucleus and cytoplasm, found in eukaryotes
- Nucleolus: A region within the nucleus where ribosomal RNA is synthesized, found in eukaryotes
- Nucleoid: A region within the cytoplasm where DNA is localized in prokaryotes, not membrane-bound
- Mitochondrion (Mitochondria): Site of cellular respiration, responsible for ATP production, found in eukaryotes
- Chloroplast: Site of photosynthesis, found in plants and algae
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Cytoskeleton: A network of protein filaments that provides structural support, helps with movement, and assists in cell division, found in both prokaryotes and eukaryotes
- Microtubules: Hollow tubes made of tubulin, involved in cell shape, movement of organelles, and chromosome separation during cell division
- Microfilaments: Solid rods made of actin, involved in cell shape, muscle contraction, and cytoplasmic streaming
- Ribosomes: Sites of protein synthesis, found in both prokaryotes and eukaryotes
- Plasmids: Small circular DNA molecules found in prokaryotes, often carry genes for antibiotic resistance
Mitosis
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Mitotic Cell Cycle: A series of events that lead to cell division, including:
- G1 Phase: Cell growth and prepares for DNA replication
- S Phase: DNA replication occurs
- G2 Phase: Cell prepares for mitosis
- M Phase: Mitosis and cytokinesis occur
- Basic Results of Mitosis: Two genetically identical daughter cells, each with the same number of chromosomes as the original cell
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Chromosome Structure:
- Unreplicated Chromosome: A single, linear molecule of DNA
- Replicated Chromosome: Two identical sister chromatids joined at the centromere
- Centromere: The region where sister chromatids are attached
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Terminology:
- Sister Chromatids: Two identical copies of a chromosome held together at the centromere
- Non-Sister Chromatids: Chromatids from homologous chromosomes
- Homologous Chromosomes: Chromosomes that carry the same genes in the same order
- Non-Homologous Chromosomes: Chromosomes that carry different genes
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Ploidy Level:
- Diploid (2n): Cells containing two sets of chromosomes
- Haploid (n): Cells containg one set of chromosomes
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Functions of Mitosis:
- Growth and Development: Increases the number of cells in an organism
- Repair and Renewal: Replaces damaged or lost cells
- Asexual Reproduction: Some organisms reproduce asexually through mitosis
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Stages of Mitosis:
- Prophase: Chromosomes condense, nuclear envelope breaks down, mitotic spindle forms
- Prometaphase: Chromosomes align at the metaphase plate, mitotic spindle fibers attach to kinetochores
- Metaphase: Chromosomes align at the metaphase plate, spindle fibers are fully attached
- Anaphase: Sister chromatids separate and move to opposite poles
- Telophase: Chromosomes decondense, nuclear envelope reforms, cytokinesis begins
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Differences between Animal and Plant Cells in Mitosis:
- Animal Cells: Cleavage furrow forms to divide the cytoplasm
- Plant Cells: Cell plate forms to divide the cytoplasm
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Terminology:
- Centrosome: A structure that organizes microtubules
- Aster: A radial array of microtubules emanating from the centrosome
- Microtubules: Hollow protein tubes that make up the spindle fibers
- Spindle Fibers: Microtubules that attach to chromosomes during mitosis
- Mitotic Spindle: The structure consisting of spindle fibers that helps separate chromosomes during mitosis
- Kinetochore: A protein complex that attaches spindle fibers to chromosomes
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Cytokinesis: The division of the cytoplasm after mitosis
- Animal Cells: Cleavage furrow forms, pinching in the cell membrane to divide the cytoplasm
- Plant Cells: Cell plate forms, growing from the center outwards towards the cell walls to divide the cytoplasm
Asexual vs Sexual Life Cycles
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Asexual Reproduction: A single parent produces genetically identical offspring, no genetic variation
- Types: Budding, fragmentation, fission
- Sexual Reproduction: Two parents contribute genetic material to produce offspring, genetic variation
- Animal Sexual Life Cycle: Diploid (2n) stage is dominant, haploid gametes (sperm and egg) fuse during fertilization to form a diploid zygote
- Fungal Sexual Life Cycle: Haploid (n) stage is dominant, haploid spores fuse to form a diploid zygote
- Plant Sexual Life Cycle: Alternation of generations, with both diploid (sporophyte) and haploid (gametophyte) stages
Meiosis
- Basic Outcome: Four haploid (n) daughter cells, each genetically unique and half the number of chromosomes as the original parental cell
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Meiosis I:
- Synapsis: Homologous chromosomes pair up side-by-side
- Crossing Over: Exchange of genetic material between homologous chromosomes, occurs during prophase I
- Independent Alignment: Homologous pairs align randomly at the metaphase plate, contributing to genetic variation
- Segregation of Homologs: Homologous chromosomes separate and move to opposite poles during anaphase I
- Meiosis II: Similar to mitosis, but with haploid cells, sister chromatids separate during anaphase II
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Terminology:
- Haploid (n): Cells with one set of chromosomes
- Diploid (2n): Cells with two sets of chromosomes
- Homologous Chromosomes: Chromosomes that carry the same genes in the same order
- Synapsis: Pairing of homologous chromosomes
- Crossing Over: Exchange of genetic material between homologous chromosomes
- Independent Alignment: Random alignment of homologous chromosome pairs at the metaphase plate
Mendelian Genetics
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Terminology:
- Gene: A unit of heredity that occupies a specific locus on a chromosome
- Allele: Alternative forms of a gene
- Genotype: The genetic makeup of an individual
- Phenotype: The observable characteristics of an individual
- Heterozygote: An individual carrying two different alleles for a gene
- Homozygote: An individual carrying two identical alleles for a gene
- Dominant Allele: An allele that masks the expression of the recessive allele
- Recessive Allele: An allele whose expression is masked by the dominant allele
- True-Breeding Line: Individuals that produce offspring with the same phenotype when self-crossed
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Three Important Crosses:
- AA x aa: Parental cross, produces all heterozygous offspring
- Aa x Aa: Dihybrid cross, produces offspring with a 1:2:1 genotypic ratio and a 3:1 phenotypic ratio
- Aa x aa: Test cross, used to determine the genotype of an unknown individual
- Two-Gene Crosses: Involve two unlinked genes (located on different chromosomes), exhibit independent assortment
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Mendel's Laws of Inheritance:
- Law of Segregation: Alleles at a gene segregate during meiosis
- Law of Independent Assortment: Alleles at different genes segregate independently of each other
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Solving Genetic Problems:
- Punnett Squares: Diagrammatic method used to predict the genotypes and phenotypes of offspring
- Rules of Probability: Used to calculate the probabilities of specific outcomes
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Mendelian Genetics and Hypothesis Testing:
- Developing Hypotheses: Formulate an educated guess about the pattern of inheritance
- Making Predictions: Predict the expected outcomes of genetic crosses
- Testing Predictions: Perform genetic crosses and compare the observed results to the predictions
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Interpreting Genetic Data:
- Compare Observed to Expected: Determine if the observed data agrees with the predictions
- Support or Refute Hypotheses: Determine whether the data support the original hypothesis
- Test Cross: Used to determine the genotype of an unknown individual, involves crossing the unknown individual with a homozygous recessive individual
- Reciprocal Cross: Used to determine if the sex of the parent influences the pattern of inheritance, involves crossing the parents with the reciprocal genders
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Variations on Single-Gene Crosses:
- Sex-Linked Traits: Genes located on sex chromosomes, often exhibit different inheritance patterns in males and females
- Multiple Alleles: More than two alleles for a gene exist in a population
- Dominance Hierarchies: Different alleles exhibit different levels of dominance
- Incomplete Dominance: Heterozygotes exhibit an intermediate phenotype
- Co-dominance: Both alleles are expressed simultaneously in the heterozygote
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Description
Test your knowledge on cell structure and the differences between prokaryotes and eukaryotes. This quiz covers key concepts such as the three domains of life, cell membranes, and organelles. Perfect for biology students wanting to enhance their understanding of cellular biology.