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Questions and Answers
What is the primary function of cells in living organisms?
What is the primary function of cells in living organisms?
Which statement accurately describes eukaryotic cells?
Which statement accurately describes eukaryotic cells?
Which organism is a typical example of a prokaryotic cell?
Which organism is a typical example of a prokaryotic cell?
What is a key characteristic of prokaryotic cells?
What is a key characteristic of prokaryotic cells?
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What does the term 'anabolism' refer to in cellular metabolism?
What does the term 'anabolism' refer to in cellular metabolism?
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Which of the following statements is part of modern cell theory?
Which of the following statements is part of modern cell theory?
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What role do mitochondria serve in eukaryotic cells?
What role do mitochondria serve in eukaryotic cells?
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Which of the following is NOT a characteristic of prokaryotic cells?
Which of the following is NOT a characteristic of prokaryotic cells?
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What is the primary function of the nucleus in a eukaryotic cell?
What is the primary function of the nucleus in a eukaryotic cell?
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What is the role of nuclear pore complexes?
What is the role of nuclear pore complexes?
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What substance is primarily found in the nucleolus?
What substance is primarily found in the nucleolus?
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How does the number of mitochondria vary across different cell types?
How does the number of mitochondria vary across different cell types?
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Which of the following statements about chromatin is true?
Which of the following statements about chromatin is true?
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What is the significance of the nucleoplasm?
What is the significance of the nucleoplasm?
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Which feature of mitochondria can change based on metabolic conditions?
Which feature of mitochondria can change based on metabolic conditions?
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Which statement accurately describes the function of the nucleolus?
Which statement accurately describes the function of the nucleolus?
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What percentage of membrane lipids in grey matter cells are gangliosides?
What percentage of membrane lipids in grey matter cells are gangliosides?
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Which organisms lack cholesterol in their biomembranes?
Which organisms lack cholesterol in their biomembranes?
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How are integral membrane proteins characterized in relation to the membrane structure?
How are integral membrane proteins characterized in relation to the membrane structure?
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What physical characteristic of cholesterol contributes to its function in membrane fluidity?
What physical characteristic of cholesterol contributes to its function in membrane fluidity?
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What defines peripheral membrane proteins compared to integral membrane proteins?
What defines peripheral membrane proteins compared to integral membrane proteins?
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Which compartment of the Golgi complex is primarily responsible for receiving newly synthesized proteins from the ER?
Which compartment of the Golgi complex is primarily responsible for receiving newly synthesized proteins from the ER?
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What type of modifications occur in the Golgi lumen?
What type of modifications occur in the Golgi lumen?
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What is the primary role of secretory vesicles in the Golgi complex?
What is the primary role of secretory vesicles in the Golgi complex?
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Which genetic disease is associated with mutations in the genes encoding Golgi proteins?
Which genetic disease is associated with mutations in the genes encoding Golgi proteins?
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What characterizes the Golgi complex in terms of protein sorting?
What characterizes the Golgi complex in terms of protein sorting?
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Which term describes the function of lysosomes?
Which term describes the function of lysosomes?
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In which year were lysosomes first identified and characterized?
In which year were lysosomes first identified and characterized?
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Which diseases are associated with Golgi stacks dispersion?
Which diseases are associated with Golgi stacks dispersion?
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Which of the following enzymes is primarily used as a marker for lysosomes?
Which of the following enzymes is primarily used as a marker for lysosomes?
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What is the optimal pH range for lysosomal enzymes to function effectively?
What is the optimal pH range for lysosomal enzymes to function effectively?
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Which process allows cellular organelles to be digested within lysosomes?
Which process allows cellular organelles to be digested within lysosomes?
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What occurs when lysosomal membranes rupture during cell death?
What occurs when lysosomal membranes rupture during cell death?
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Which type of enzyme is NOT classified as a lysosomal enzyme?
Which type of enzyme is NOT classified as a lysosomal enzyme?
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How can lysosomal dysfunction contribute to allergic responses?
How can lysosomal dysfunction contribute to allergic responses?
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What special role does the acrosome, a specialized lysosome, play?
What special role does the acrosome, a specialized lysosome, play?
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What type of enzymes are lipases classified as?
What type of enzymes are lipases classified as?
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What characteristic of lipids allows them to form cell membranes?
What characteristic of lipids allows them to form cell membranes?
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Which fatty acid is the most abundant unsaturated fatty acid found in animal membrane lipids?
Which fatty acid is the most abundant unsaturated fatty acid found in animal membrane lipids?
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What impact does the degree of unsaturation in fatty acids have on cell membranes?
What impact does the degree of unsaturation in fatty acids have on cell membranes?
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Which of the following is NOT a type of glycerophospholipid?
Which of the following is NOT a type of glycerophospholipid?
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What is the common composition of the nonpolar tails in most membrane lipids?
What is the common composition of the nonpolar tails in most membrane lipids?
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Which type of lipid is primarily found in the nervous system tissue?
Which type of lipid is primarily found in the nervous system tissue?
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How are saturated fatty acid groups characterized?
How are saturated fatty acid groups characterized?
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What percentage of the fatty acid groups are typically saturated in membrane lipids?
What percentage of the fatty acid groups are typically saturated in membrane lipids?
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Study Notes
Cell Structure and Function Overview
- Cells are the fundamental units of life in all animals, including humans
- Cells are the building blocks of tissues
- When cells die, tissues perish and stop functioning
Cell Theory
- All organisms are composed of cells
- All cells come from pre-existing cells
- Cells contain the genetic information necessary for their functions and reproduction
- Metabolism encompasses all chemical reactions occurring within cells, including anabolism and catabolism
Types of Cells
- Two types of cells exist: prokaryotic and eukaryotic
- Prokaryotic cells are simpler and smaller than eukaryotic cells. They lack membrane-bound organelles and a nucleus.
- Eukaryotic cells are more complex and larger than prokaryotic cells. They possess membrane-bound organelles and a nucleus.
Prokaryotic Cells Characteristics
- Minimal internal organization and smaller in size
- Lack membrane-bound organelles
- Genetic material (DNA) is not enclosed by a nuclear membrane
- DNA is not complexed with histones, a protein found in eukaryotic DNA
- Respiratory system closely associated with the plasma membrane
- Sexual reproduction does not involve mitosis or meiosis.
Eukaryotic Cells Characteristics
- A high degree of internal organization with many internal membrane-bound organelles
- The nucleus contains the genetic material (DNA) enclosed by a double membrane
- The genetic material is complexed with proteins called histones
- Have a specific/well-defined nucleus, mitochondria
- Sexual reproduction involves both mitosis and meiosis
- Respiratory site includes the mitochondria
Cell Organelles: Nucleus
- The nucleus contains most of a cell's DNA
- The control center of the eukaryotic cell
- Nuclear envelope: double membrane structure separating the nucleus from the cytoplasm
- Nuclear pore complexes: embedded in the nuclear envelope controlling the movement of proteins and nucleic acids (RNAs) across the nuclear envelope
- Chromatin: DNA in the nucleus coiled into a dense mass
- Nucleolus: A second dense mass closely associated with the inner nuclear envelope responsible for rRNA synthesis and ribosome subunit assembly
- Nucleoplasm: The nucleoplasm of the nucleus contains enzymes such as DNA polymerases and RNA polymerases for mRNA and tRNA synthesis
Cell Organelles: Mitochondria
- Mitochondria are the "powerhouses" of the cell
- Numerous in some cells, few in others
- Vary in shape and size
- Found in virtually all eukaryotic cells
- The number of mitochondria in a cell varies dramatically; some contain only one, while others can contain thousands
- Mitochondrial membranes: Outer Mitochondrial membrane: mostly phospholipids and cholesterol, containing the protein Porin. Inner Mitochondrial membrane: highly folded (cristae)
- Intermembrane space: located between the inner and outer membrane
- Mitochondrial Matrix: The region enclosed by the inner membrane containing enzymes for the citric acid cycle, fatty acid oxidation, and synthesis of certain proteins
- DNA in the matrix is partly independent (semi-autonomous)
- Mitochondria are involved in Parkinson's disease, a neurodegenerative disorder, where they do not function correctly
Cell Organelles: Endoplasmic Reticulum (ER)
- Extends from the cell membrane, coats the nucleus, and surrounds the mitochondria
- Involved in protein synthesis, transport, modification, storage, and secretion
- Rough ER: covered in ribosomes, involved in protein synthesis
- Smooth ER: lacks ribosomes, involved in lipid synthesis and detoxification
Cell Organelles: Golgi Complex (Golgi Apparatus)
- These are unique stacks of smooth compartments in eukaryotic cells, often associated with ER
- Has a Proximal compartment, Medial compartment, and a Distal compartment
- Golgi complexes sort and modify proteins for transport within the cell or secretion outside the cell
- proteins without signaling or transit peptides are rejected
Cell Organelles: Lysosomes
- Contain packets of enzymes
- Involved in cellular digestion (break-down of molecules)
- Important in autophagy (cell's self-digestion) and in the death (autolysis) of cells
- Lysosomal enzymes have an optimal pH of around 5
Cell Organelles: Peroxisomes
- Small organelles also called Microbodies, present in eukaryotic cells
- No energy-coupled electron transport systems
- Involved in oxidation reactions involving hydrogen peroxide; destroyed by catalase enzyme
- Oxidizing long-chain fatty acids located in liver peroxisomes
Cell Organelles: Cytoplasm (Cytosol)
- Simplest structure of the cell
- Contains organelles-free sap (cytosol)
- Many metabolic reactions occur in cytosol
- Contains proteins, ribosomal RNA (rRNA), and free ribosomes (polysome form)
- Contains necessary substrates and cofactors that interact with various enzymes
Biological Membranes Structure and Function
- Plasma membrane, a prototype cell membrane, extensively studied
- Separates cell contents from the outer environment acting as a barrier and a regulator
- Has selective permeability, controlling molecule and ion flow
- Contains surface molecules for cell recognition and communication
- Eukaryotic cells have internal membrane systems surrounding organelles, assisting their function
Biological Membranes Chemical Composition
- Membranes consist of lipids, proteins, and carbohydrates
- Lipids (mostly phospholipids and cholesterol) form the basis of membranes, while proteins are embedded in or associated with them
- Proteins and carbohydrates are covalently attached to the membrane lipids; lipids are about 40% of the dry weight, proteins 60%, and carbohydrates 1-10%
- Composition of different membranes can vary significantly
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Description
This quiz explores the fundamental principles of cell structure and function, including the cell theory and the distinction between prokaryotic and eukaryotic cells. Understand the critical role of cells as the building blocks of life and their importance in biological systems.