quiz image

THE CELL WK1 - Building block of cell

ModernPortland avatar
ModernPortland
·
·
Download

Start Quiz

Study Flashcards

76 Questions

What is the primary mechanism by which integral proteins are held in place within the lipid bilayer?

Hydrophobic segments interacting with the protein hydrophobic interior of the lipid bilayer

Which type of protein is covalently attached to a lipid and embedded in the lipid bilayer?

Lipid-anchored protein

What is the main function of membrane proteins in terms of molecular ionic compositions of cellular compartments?

To regulate the molecular ionic compositions of cellular compartments

What is a characteristic of peripheral proteins?

They are hydrophilic and located on the membrane surface

What is the overall function of the cell membrane dependent on?

Both lipids and proteins

What is the function of membrane proteins in terms of the flow of information between cells?

To control the flow of information

Which type of protein is typically associated with the surface of the membrane and is linked noncovalently to the polar heads of phospholipids?

Peripheral protein

What is the main function of membrane proteins in terms of protein production?

To produce proteins activated via signaling pathways

What determines the function of a membrane protein?

The protein's interactions with the lipid bilayer

What is the primary function of the cell membrane?

To serve as a selective barrier for the cell

Which of the following proteins is NOT directly involved in cell-cell interactions?

Membrane enzyme

What is the function of cholesterol in the cell membrane?

To provide structural support

What is the main difference between integral and peripheral proteins?

Their association with the lipid bilayer

What is the role of amphipathic lipids in the cell membrane?

To form a hydrophobic and hydrophilic region

Which of the following is a characteristic of the fluid mosaic model?

A dynamic and fluid structure

What is the function of membrane receptors?

To serve as a connection between the cell's internal and external environments

Which of the following lipids is NOT a component of the cell membrane?

Terpenes

What is the role of transport proteins in the cell membrane?

To facilitate the transport of ions and molecules

What is the function of lipid-anchored proteins?

To interact with the lipid bilayer and facilitate cellular functions

What determines the permeability of a substance through a membrane?

Thickness of the bilipid layer

What type of transport involves the simultaneous movement of two solutes in the same or opposite directions?

Coupled transport

What is the function of receptors in a cell?

To bind signaling molecules and initiate a physiological response

What is a characteristic of ion channel receptors?

They are multimeric proteins that form a passageway through the membrane

What is the role of the alpha subunit in G-protein coupled receptors?

It binds to GTP or GDP depending on activation

What is the function of protein tyrosine phosphatase (PTP) in enzyme-linked receptors?

It removes phosphates and deactivates the receptor

What type of receptors are receptor tyrosine kinases (RTKs)?

Enzyme-linked receptors

What is the primary function of carrier proteins in membrane transport?

To transport solutes across the membrane

What is the energy requirement for secondary active transport?

Gradient power of another transport process

What is the function of electron transport proteins in mitochondria?

Energy production

What is the characteristic of the cell membrane's structure?

Dynamic and fluid

What is the function of receptors in the cell membrane?

Binding of hormone or signal molecules

What is the purpose of selective permeability of the cell membrane?

To regulate the flow of substances into and out of the cell

What is the difference between integral proteins and peripheral proteins?

Integral proteins are embedded in the membrane, while peripheral proteins are attached

What is the function of lipid-anchored proteins?

To regulate protein-protein interactions

What is the purpose of vesicles in the cell?

To transport materials within the cell

What is the role of fatty acid composition in the cell membrane?

To influence the fluidity of the membrane

What is the relationship between the cell membrane and organelles?

The cell membrane surrounds organelles

How do membrane proteins regulate the molecular ionic compositions of cellular compartments?

They control the flow of ions and molecules across the membrane.

What determines the function of a membrane protein in terms of its interaction with the lipid bilayer?

The type of protein-lipid bilayer interaction, such as integral, peripheral, or lipid-anchored.

How do membrane proteins control the flow of information between cells?

They regulate the signaling pathways and transmission of information between cells.

What is the significance of the lipid bilayer in membrane protein function?

It provides a specific environment for protein-lipid interactions and affects protein function.

What is the key role of integral proteins in the cell membrane, and how are they differentiated from peripheral proteins?

Integral proteins are embedded in the lipid bilayer and play a crucial role in various cellular functions, such as transport and signaling. They are differentiated from peripheral proteins, which are attached to the surface of the membrane, but not embedded in the lipid bilayer.

How do membrane proteins embedded in lipid layers contribute to the production of proteins?

They are activated via signaling pathways, and their expression is regulated by differential transcription of genes.

Explain how lipid-anchored proteins are attached to the cell membrane, and what is their primary function?

Lipid-anchored proteins are attached to the cell membrane through covalent bonds with lipids, and their primary function is to facilitate cell-cell interactions and signaling.

What is the primary function of integral proteins in the cell membrane?

To facilitate the transport of molecules across the membrane and maintain the cell's internal environment

What is the relationship between the function of a membrane protein and its association with the lipid bilayer?

The function of a membrane protein is reflected in its association with the lipid bilayer.

How do peripheral proteins interact with the lipid bilayer?

Through non-covalent bonds with the polar heads of phospholipids

What is the role of fatty acid composition in the fluidity of the cell membrane?

The fatty acid composition of the cell membrane determines its fluidity, with unsaturated fatty acids and chain length influencing the membrane's dynamic structure.

What is the characteristic of lipid-anchored proteins?

They are covalently attached to a lipid and embedded in the lipid bilayer

Describe the role of receptors in the cell membrane, and how they facilitate intercellular communication.

Receptors are proteins embedded in the cell membrane that bind to specific signal molecules, triggering an intracellular response and facilitating intercellular communication.

What is the role of membrane proteins in terms of cell signaling?

To facilitate communication between cells and their environment

Explain the concept of selective permeability of the cell membrane, and its importance in cellular function.

Selective permeability refers to the ability of the cell membrane to regulate the passage of certain substances, while restricting others. This is crucial for maintaining proper cellular function and homeostasis.

What is the primary function of electron transport proteins in mitochondria, and how do they facilitate energy production?

Electron transport proteins are involved in the process of energy production in mitochondria, facilitating the transfer of electrons during cellular respiration.

How do amphipathic lipids contribute to the structure of the cell membrane?

They form a lipid bilayer with a hydrophobic tail and a hydrophilic head

What is the function of membrane receptors in terms of cell-cell interactions?

To facilitate recognition and communication between cells

Describe the role of integral proteins in solute transport across the cell membrane, and how they facilitate this process.

Integral proteins create hydrophilic and hydrophobic passageways, allowing for the transport of nutrients and other solutes across the cell membrane.

How do transport proteins contribute to the maintenance of cellular homeostasis?

By regulating the flow of ions and molecules across the cell membrane

Explain the concept of vesicles, and their role in cellular transport and secretion.

Vesicles are structures consisting of liquid or cytoplasm enclosed by a lipid bilayer, formed during secretion, uptake, and transport of materials within the plasma membrane.

What is the characteristic of the fluid mosaic model?

A lipid bilayer with embedded proteins

What is the role of enzymes in the cell membrane, and how do they facilitate specific cellular functions?

Enzymes are proteins embedded in the cell membrane that facilitate specific cellular functions, such as energy production and solute transport.

What is the function of membrane enzymes in terms of cell function?

To facilitate various cellular reactions and processes

How do structural proteins contribute to the stability of the cell membrane?

By attaching to microfilaments in the cytoskeleton

What is the primary function of integral proteins in the membrane, and how are they differentiated from peripheral proteins?

Integral proteins span the membrane and have a hydrophobic region that interacts with the lipid bilayer, whereas peripheral proteins are bound to the membrane surface and do not span the membrane.

How do lipid-anchored proteins interact with the lipid bilayer, and what is their functional significance?

Lipid-anchored proteins are covalently linked to lipids and embedded in the lipid bilayer, allowing them to participate in cell signaling and membrane trafficking.

What is the main function of membrane proteins in terms of molecular and ionic compositions of cellular compartments?

Membrane proteins regulate the transport of molecules and ions across the membrane, maintaining the molecular and ionic compositions of cellular compartments.

How do receptor proteins facilitate signaling across the membrane, and what is the significance of their binding to signaling molecules?

Receptor proteins bind to signaling molecules outside the cell and initiate a physiological response by transmitting signals across the membrane.

What is the characteristic feature of ion channel receptors, and how do they regulate ion flow across the membrane?

Ion channel receptors are multimeric proteins that form a passageway across the membrane, allowing specific ions to flow through them in response to chemical or mechanical signals.

How do G-protein coupled receptors transmit signals across the membrane, and what is the role of the alpha subunit?

G-protein coupled receptors transmit signals by binding to signaling molecules, which activates the alpha subunit, leading to dissociation of the G-protein complex and diffusion to interact with other membrane-bound proteins.

What is the primary function of carrier proteins in membrane transport, and how do they facilitate transport across the membrane?

Carrier proteins facilitate transport by binding to solutes and transporting them across the membrane, either alone (uniport) or in conjunction with other solutes (coupled transport).

How does the permeability of a substance through a membrane depend on the properties of the substance and the membrane?

The permeability of a substance through a membrane depends on the substance's size, charge, and lipid solubility, as well as the membrane's lipid composition and protein-mediated transport mechanisms.

What is the significance of secondary active transport in maintaining cellular homeostasis, and how is it driven?

Secondary active transport involves the transport of solutes against their concentration gradient, driven by the energy generated from the formation of another ion gradient.

What are Gap Junctions in intercellular transport?

Protein channels that allow direct exchange of ions, nutrients, and waste between cells

What are Gap junctions composed of?

Connexin protein molecules

What are tight junctions in intercellular transport?

efine apical and basolateral plasma membrane domains in polarised epithelial cells and control the flow of solutes between cells in an epithelial sheet.

What is TrK receptor binding?

A mechanism of cell signaling

What is TrkB receptor binding?

Brain-Derived Neurotrophic Factor (BDNF) binding

Study Notes

Cell Membrane Structure

  • Phospholipid bilayer: a fluid state of membrane that allows nuclear transfer during cloning
  • Contains phosphoglycerides, sphingolipids, and sterols
  • Phospholipid: 2 fatty acid with glycerol backbone associated with a modified phosphate group and simple organic molecules (e.g., Choline)
  • Amphipathic lipid with phosphate-based head group and 2-pronged hydrophobic tail

Protein Movement and Types

  • Proteins in the membrane undergo rotation on long axis, lateral diffusion, and transverse diffusion
  • Three main types of proteins:
    • Integral proteins: embedded in lipid bilayer, hydrophobic segments interact with lipid bilayer
    • Peripheral proteins: hydrophilic, located on surface of membrane, linked noncovalently to polar heads of phospholipids
    • Lipid-anchored proteins: hydrophilic, covalently attached to lipid and embedded in bilayer

Main Classes of Membrane Proteins

  • Myelin
  • Plasma membrane
  • Energy transduction membranes

Functions of Membrane Proteins

  • Regulate molecular ionic compositions of cellular compartments
  • Control flow of information between cells
  • Proteins embedded in lipid layers: specific to substance and transport
  • Production of proteins activated via signalling pathways, regulated by differential transcription of genes

Fluid Mosaic Model

  • Lipid bilayer: proteins embedded in
  • Fluid part: lipid
  • Main components: proteins, carbohydrates, and cholesterol
  • Structure: cell adhesion molecules, structural proteins, membrane enzymes, membrane receptors, and transport proteins

Membrane Transport

  • Solutes have higher concentration inside organelle than outside
  • Major aspect: transport of ions and organic molecules
  • Permeability of molecule bilipid layer and availability of energy source
  • Two types of transport:
    • Uniport transport: transport of a single solute across the membrane
    • Coupled transport: simultaneous transport of two solutes in the same or opposite direction

Receptors

  • Bind signalling molecules outside the cell and initiate physiological response
  • Three main classes:
    • Ion channel receptors: multimeric proteins, specific to particular ions, open and close in response to chemical and mechanical signals
    • G-protein coupled receptors: alpha subunit binds to GTP or GDP, subunits dissociate and interact with other membrane-bound proteins
    • Enzyme-linked receptors: receptor tyrosine kinases (RTKs), regulated by protein tyrosine phosphate (PTP)

Vesicles

  • Structure within or outside a cell, consisting of liquid or cytoplasm enclosed by a lipid bilayer
  • Form naturally during secretion, uptake, and transport of materials within the plasma membrane

This quiz covers the movement of phospholipid molecules within membranes, including rotation, lateral diffusion, and transverse diffusion. It also covers the mosaic fluid model of proteins, including integral and peripheral proteins.

Make Your Own Quizzes and Flashcards

Convert your notes into interactive study material.

Get started for free

More Quizzes Like This

Use Quizgecko on...
Browser
Browser