Cell Junctions and Epithelial Functions
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Questions and Answers

What is the primary function of tight junctions?

  • To connect intermediate filaments of cells
  • To restrict the movement of fluids between adjacent cells (correct)
  • To form a continuous belt around cells
  • To anchor cells to the basal lamina

    • Which proteins are integral to forming tight junctions?

  • Cadherins and catenins
  • Claudin and occludin (correct)
  • Laminin and collagen
  • Desmoplakin and plakoglobin

    • What is the relationship between cadherins and adherens junctions?

  • Cadherins interact to 'zipper' cells together (correct)
  • Cadherins form the same structure as tight junctions
  • Cadherins bind to intermediate filaments
  • Cadherins are involved in signaling between cells

    • What distinguishes a desmosome from other cell junctions?

    <p>It is a disk-shaped structure matching adjacent cells</p> Signup and view all the answers

    What is the primary function of the apical domain of epithelial cells?

    <p>Projects towards the external surface or lumen.</p> Signup and view all the answers

    What role do hemidesmosomes play in epithelial cells?

    <p>They connect cells to the extracellular matrix</p> Signup and view all the answers

    Which type of protein do desmosomes use to bind adjacent cells?

    <p>Cadherins</p> Signup and view all the answers

    Which of the following accurately describes the composition of the basement membrane?

    <p>Has a basal lamina and fibrous reticular lamina.</p> Signup and view all the answers

    What structure do adherens junctions create between adjacent epithelial cells?

    <p>A continuous belt around the cells</p> Signup and view all the answers

    Which type of junction is responsible for preventing leakage of transported solutes and water between epithelial cells?

    <p>Tight junctions</p> Signup and view all the answers

    What key role does the basal lamina play in epithelial tissue?

    <p>Acts as a guide for cell regeneration.</p> Signup and view all the answers

    What is the main function of the proteins found in hemidesmosomes?

    <p>To serve as receptor sites for extracellular macromolecules</p> Signup and view all the answers

    Which term refers to the intercellular junctions that allow communication between adjacent epithelial cells?

    <p>Nexus (gap junctions)</p> Signup and view all the answers

    In epithelial cells, where do the lateral domain structures exist?

    <p>Interconnecting adjacent cells.</p> Signup and view all the answers

    Which component is NOT a constituent of the basement membrane?

    <p>Fibrinogen</p> Signup and view all the answers

    Which of the following is NOT a characteristic of epithelial cells?

    <p>They are vascularized.</p> Signup and view all the answers

    What structures are formed by pairs of abutting particles known as connexons?

    <p>Gap junctions</p> Signup and view all the answers

    Which of the following correctly describes microvilli?

    <p>Short finger-like projections found on some epithelial cells</p> Signup and view all the answers

    What is the primary function of stereocilia?

    <p>Absorption and mechanical sensory reception</p> Signup and view all the answers

    Which structural component is common in both microvilli and cilia?

    <p>Actin filaments</p> Signup and view all the answers

    Cilia are typically classified by how many pairs of microtubules do they contain?

    <p>9</p> Signup and view all the answers

    What is affected in celiac disease regarding the intestinal cells?

    <p>Loss of microvilli brush border</p> Signup and view all the answers

    Where would you typically find stereocilia?

    <p>Epididymis and inner ear</p> Signup and view all the answers

    What proteins are associated with the actin core of microvilli?

    <p>Fascin, espin, and fimbrin</p> Signup and view all the answers

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