Cell Junctions and Cell Adhesion Molecules Quiz

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Which transmembrane protein is essential for the assembly and function of tight junctions?

Tricellulin

Occludin

Cadherins

Claudins (correct)

What is the major function of anchoring junctions in animal tissues?

Secrete extracellular matrix

Facilitate cell signaling

Connect cytoskeletal elements of neighboring cells (correct)

Enable selective permeability

In which type of junction do the transmembrane linker proteins belong to the integrin family?

Hemidesmosomes (correct)

Tight junctions

Adherens junctions

Desmosomes

What is the main role of desmosomes in cell adhesion?

Connecting adjacent plasma membranes Signup and view all the answers

How do hemidesmosomes differ from desmosomes in terms of cellular attachment?

Connect to neighboring cells instead of the basal lamina Signup and view all the answers

Which proteins are involved in the binding of integrin β4 to plectin 1a in hemidesmosomes?

CD151 and BPAG2 Signup and view all the answers

What is the key role of integrins in cancer progression?

Supporting oncogenic growth factor receptor (GFR) signaling Signup and view all the answers

How does gap junction electrical coupling differ from tight junctions?

Gap junctions form continuous aqueous channels between cells Signup and view all the answers

Why do cardiac muscle cells and cells of the heart's electrical conduction system remain electrically insulated from each other?

Because of incompatible connexins in the connexons Signup and view all the answers

How do hemidesmosomes compare to desmosomes?

Hemidesmosomes have a direct connection with keratin IFs, while desmosomes do not involve keratin. Signup and view all the answers

Cell Junctions and Cell Adhesion Molecules Quiz

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Questions and Answers

Which transmembrane protein is essential for the assembly and function of tight junctions?

What is the major function of anchoring junctions in animal tissues?

In which type of junction do the transmembrane linker proteins belong to the integrin family?

What is the main role of desmosomes in cell adhesion?

How do hemidesmosomes differ from desmosomes in terms of cellular attachment?

Which proteins are involved in the binding of integrin β4 to plectin 1a in hemidesmosomes?

What is the key role of integrins in cancer progression?

How does gap junction electrical coupling differ from tight junctions?

Why do cardiac muscle cells and cells of the heart's electrical conduction system remain electrically insulated from each other?

How do hemidesmosomes compare to desmosomes?

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