Cell Junctions and Cell Adhesion Molecules Quiz
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Questions and Answers

Which transmembrane protein is essential for the assembly and function of tight junctions?

  • Tricellulin
  • Occludin
  • Cadherins
  • Claudins (correct)

What is the major function of anchoring junctions in animal tissues?

  • Secrete extracellular matrix
  • Facilitate cell signaling
  • Connect cytoskeletal elements of neighboring cells (correct)
  • Enable selective permeability

In which type of junction do the transmembrane linker proteins belong to the integrin family?

  • Hemidesmosomes (correct)
  • Tight junctions
  • Adherens junctions
  • Desmosomes

What is the main role of desmosomes in cell adhesion?

<p>Connecting adjacent plasma membranes (A)</p> Signup and view all the answers

How do hemidesmosomes differ from desmosomes in terms of cellular attachment?

<p>Connect to neighboring cells instead of the basal lamina (D)</p> Signup and view all the answers

Which proteins are involved in the binding of integrin β4 to plectin 1a in hemidesmosomes?

<p>CD151 and BPAG2 (D)</p> Signup and view all the answers

What is the key role of integrins in cancer progression?

<p>Supporting oncogenic growth factor receptor (GFR) signaling (C)</p> Signup and view all the answers

How does gap junction electrical coupling differ from tight junctions?

<p>Gap junctions form continuous aqueous channels between cells (C)</p> Signup and view all the answers

Why do cardiac muscle cells and cells of the heart's electrical conduction system remain electrically insulated from each other?

<p>Because of incompatible connexins in the connexons (C)</p> Signup and view all the answers

How do hemidesmosomes compare to desmosomes?

<p>Hemidesmosomes have a direct connection with keratin IFs, while desmosomes do not involve keratin. (A)</p> Signup and view all the answers

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