Cell Junctions and Cell Adhesion Molecules Quiz

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Which type of cell junctions specifically prevent small molecules from leaking across the cell sheet?

Desmosomes

Tight junctions (correct)

Hemidesmosomes

Anchoring junctions

Which of the following proteins is essential for the formation and function of tight junctions?

Claudins (correct)

Occludin

Tricellulin

Vinculin

How do hemidesmosomes differ from desmosomes in terms of function?

Hemidesmosomes connect cells through a dense cytoplasmic plaque, while desmosomes connect cells via integrins.

Hemidesmosomes connect adjacent epithelial cells, while desmosomes connect cells to the extracellular matrix. (correct)

Hemidesmosomes prevent transepithelial leakage, while desmosomes are essential for cell-cell adhesion.

Hemidesmosomes are found in heart muscle, while desmosomes are found in skin epithelium.

In the context of epithelial sheets, where are adherens junctions typically located?

Near the apex of each cell just below the tight junction Signup and view all the answers

Why are desmosomes crucial in holding cells together, as illustrated by certain skin diseases?

They physically connect cells and disruption leads to severe blistering. Signup and view all the answers

Which proteins are key components of type I hemidesmosomes?

Integrin subunits α6 and β4 Signup and view all the answers

What is the main function of integrins in cancer progression?

Supporting oncogenic growth factor receptor signaling Signup and view all the answers

How do gap junctions differ from tight junctions in terms of cell membrane contact?

Gap junctions hold interacting membranes at a fixed distance Signup and view all the answers

What size molecules can pass through gap junction channels?

Molecules up to about 1000 daltons Signup and view all the answers

How do connexin Cx43 and Cx40 contribute to cell coupling in different tissues?

They insulate different cell types electrically Signup and view all the answers

Cell Junctions and Cell Adhesion Molecules Quiz

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Questions and Answers

Which type of cell junctions specifically prevent small molecules from leaking across the cell sheet?

Which of the following proteins is essential for the formation and function of tight junctions?

How do hemidesmosomes differ from desmosomes in terms of function?

In the context of epithelial sheets, where are adherens junctions typically located?

Why are desmosomes crucial in holding cells together, as illustrated by certain skin diseases?

Which proteins are key components of type I hemidesmosomes?

What is the main function of integrins in cancer progression?

How do gap junctions differ from tight junctions in terms of cell membrane contact?

What size molecules can pass through gap junction channels?

How do connexin Cx43 and Cx40 contribute to cell coupling in different tissues?

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