Cell Junctions and Cell Adhesion Molecules Quiz
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Questions and Answers

Which type of cell junctions specifically prevent small molecules from leaking across the cell sheet?

  • Desmosomes
  • Tight junctions (correct)
  • Hemidesmosomes
  • Anchoring junctions
  • Which of the following proteins is essential for the formation and function of tight junctions?

  • Claudins (correct)
  • Occludin
  • Tricellulin
  • Vinculin
  • How do hemidesmosomes differ from desmosomes in terms of function?

  • Hemidesmosomes connect cells through a dense cytoplasmic plaque, while desmosomes connect cells via integrins.
  • Hemidesmosomes connect adjacent epithelial cells, while desmosomes connect cells to the extracellular matrix. (correct)
  • Hemidesmosomes prevent transepithelial leakage, while desmosomes are essential for cell-cell adhesion.
  • Hemidesmosomes are found in heart muscle, while desmosomes are found in skin epithelium.
  • In the context of epithelial sheets, where are adherens junctions typically located?

    <p>Near the apex of each cell just below the tight junction</p> Signup and view all the answers

    Why are desmosomes crucial in holding cells together, as illustrated by certain skin diseases?

    <p>They physically connect cells and disruption leads to severe blistering.</p> Signup and view all the answers

    Which proteins are key components of type I hemidesmosomes?

    <p>Integrin subunits α6 and β4</p> Signup and view all the answers

    What is the main function of integrins in cancer progression?

    <p>Supporting oncogenic growth factor receptor signaling</p> Signup and view all the answers

    How do gap junctions differ from tight junctions in terms of cell membrane contact?

    <p>Gap junctions hold interacting membranes at a fixed distance</p> Signup and view all the answers

    What size molecules can pass through gap junction channels?

    <p>Molecules up to about 1000 daltons</p> Signup and view all the answers

    How do connexin Cx43 and Cx40 contribute to cell coupling in different tissues?

    <p>They insulate different cell types electrically</p> Signup and view all the answers

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