Podcast
Questions and Answers
What is the primary function of occluding junctions in epithelial cells, and what are the two proteins involved in forming sealing strands?
What is the primary function of occluding junctions in epithelial cells, and what are the two proteins involved in forming sealing strands?
The primary function of occluding junctions is to seal cells together to prevent apical and basolateral mixing and confine transport of molecules to appropriate receptors and transporters. The two proteins involved in forming sealing strands are Claudin and Occludin.
What is the difference between adherens junctions and desmosomes, and what type of filaments are they based on?
What is the difference between adherens junctions and desmosomes, and what type of filaments are they based on?
Adherens junctions are cell-cell junctions, while desmosomes are also cell-cell junctions. Both are based on actin filaments.
What is the role of intermediate filaments in anchoring junctions, and what type of proteins do they bind to?
What is the role of intermediate filaments in anchoring junctions, and what type of proteins do they bind to?
Intermediate filaments bind to dense plaques and are involved in anchoring junctions. They bind to keratinous filaments.
What is the function of gap junctions, and in which organisms are they found?
What is the function of gap junctions, and in which organisms are they found?
What is the role of myosin II in actin filament-based anchoring junctions, and how does it bind to actin?
What is the role of myosin II in actin filament-based anchoring junctions, and how does it bind to actin?
What is the role of focal adhesions and hemidesmosomes in anchoring junctions, and what type of proteins do they use to link cells to the ECM?
What is the role of focal adhesions and hemidesmosomes in anchoring junctions, and what type of proteins do they use to link cells to the ECM?
What are the components of desmosomes that are composed of desmoglein and desmocollin?
What are the components of desmosomes that are composed of desmoglein and desmocollin?
Which type of cell adhesion junctions are characterized as permanent?
Which type of cell adhesion junctions are characterized as permanent?
What is the function of hemidesmosomes?
What is the function of hemidesmosomes?
What signaling pathway is involved in linking cells via N-CAM?
What signaling pathway is involved in linking cells via N-CAM?
Which cell adhesion molecules are responsible for the transition from ectoderm to neural tube?
Which cell adhesion molecules are responsible for the transition from ectoderm to neural tube?
What type of proteins are Selectins and what types exist in the human body?
What type of proteins are Selectins and what types exist in the human body?
