Cell Injury: Morphological Types and Causes
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Questions and Answers

What type of cell injury is characterized by intracellular accumulation of water, fat, protein, cholesterol, glycogen, iron, calcium, or pigments?

  • Apoptosis
  • Reversible injury (Degeneration) (correct)
  • Irreversible injury (Cell Death)
  • Necrosis
  • Which mechanism of cell injury is characterized by cell swelling due to a defect in fluid and ion homeostasis?

  • Depletion of ATP (correct)
  • Influx of Intracellular Calcium
  • Defects in Membrane Permeability
  • Mitochondrial Damage
  • What type of cell injury is characterized by severe or prolonged cell injury?

  • Apoptosis
  • Reversible injury (Degeneration)
  • Irreversible injury (Cell Death) (correct)
  • Necrosis
  • Which factor can lead to irreversible injury (Necrosis) due to severe or prolonged cell injury?

    <p>Hypoxia</p> Signup and view all the answers

    What are some causes of reversible injury (Degeneration)?

    <p>Intracellular accumulation of water, fat, protein, cholesterol, glycogen, iron, calcium or pigments</p> Signup and view all the answers

    Study Notes

    Types of Cell Injury

    • Intracellular Accumulation: Characterized by the accumulation of substances like water, fat, protein, cholesterol, glycogen, iron, calcium, or pigments within the cell.
    • Severe or Prolonged Injury: Leads to irreversible cell damage, often resulting in necrosis, where the cell can no longer survive and function.

    Mechanisms of Cell Injury

    • Defect in Fluid and Ion Homeostasis: Causes cell swelling; this mechanism is crucial as it disrupts normal cellular function and can lead to further injury.

    Factors Leading to Irreversible Injury

    • Prolonged Severity of Damage: Factors that contribute to irreversible injury include extended exposure to harmful stimuli or stress, ultimately overwhelming the cell's reparative capabilities.

    Causes of Reversible Injury

    • Degeneration: Reversible cell injury can be caused by factors such as mild hypoxia, chemical exposure, or temporary nutrient deficiency, allowing the cell to recover once the adverse conditions are eliminated.

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    Description

    Test your knowledge on the morphological types of cell injury and the causes that lead to them. Identify types of cell injury & understand their causes including infection, physical agents, chemical agents, mechanical agents, immunologic reactions, hypoxia, and nutritional imbalances.

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