Podcast
Questions and Answers
What is cell injury?
What is cell injury?
- A condition where cells function normally.
- Disruption of cell homeostasis or steady state. (correct)
- A process of programmed cell death.
- An increase in cell size and function due to adaptation.
Cell injuries occur only inside the cell
Cell injuries occur only inside the cell
False (B)
List the three responses of a cell to injury.
List the three responses of a cell to injury.
Adaption, degeneration and death of cell
Cell injury can be reversible or irreversible. Irreversible cell injury is the progression from degeneration to death
Cell injury can be reversible or irreversible. Irreversible cell injury is the progression from degeneration to death
What are the six mechanisms of cell injury, as discussed in class?
What are the six mechanisms of cell injury, as discussed in class?
What determines the morphology of cell injury?
What determines the morphology of cell injury?
What are the three most common causes of cell injury?
What are the three most common causes of cell injury?
Which of the following is not a cause of cell injury?
Which of the following is not a cause of cell injury?
What is hypoxia?
What is hypoxia?
What is anoxia?
What is anoxia?
What are the four causes (discussed in class) of hypoxia/anoxia?
What are the four causes (discussed in class) of hypoxia/anoxia?
Match the cause of hypoxia/anoxia with its description or example
Match the cause of hypoxia/anoxia with its description or example
What are the five infectious agents as discussed in class?
What are the five infectious agents as discussed in class?
Match the type of infectious agent with its defining characteristic or example:
Match the type of infectious agent with its defining characteristic or example:
Immune system failing to respond may result from _____ (e.g. SCIDS in Arabian foals) or _____ (e.g.)) damage to lymphoid tissue due to viral infections, chemicals or drugs)
Immune system failing to respond may result from _____ (e.g. SCIDS in Arabian foals) or _____ (e.g.)) damage to lymphoid tissue due to viral infections, chemicals or drugs)
Immune system over-responding or aberrant reaction can lead to ____ (e.g. FAD, feline asthma) or ____ (e.g. systemic lupus erythematosus).
Immune system over-responding or aberrant reaction can lead to ____ (e.g. FAD, feline asthma) or ____ (e.g. systemic lupus erythematosus).
Work load imbalance often leads to _______
Work load imbalance often leads to _______
How do cells typically adapt to an increased workload?
How do cells typically adapt to an increased workload?
What cellular adaption occurs due to a decreased workload?
What cellular adaption occurs due to a decreased workload?
What are the two metabolic pathways in which ATP is produced?
What are the two metabolic pathways in which ATP is produced?
At what percentage of ATP depletion does significant cellular injury occur?
At what percentage of ATP depletion does significant cellular injury occur?
How does ATP depletion affect cellular metabolism?
How does ATP depletion affect cellular metabolism?
Which of the following structures is directly affected by ATP depletion, ultimately leading to cell necrosis?
Which of the following structures is directly affected by ATP depletion, ultimately leading to cell necrosis?
Which of the following is NOT one of the three major consequences of mitochondrial injury?
Which of the following is NOT one of the three major consequences of mitochondrial injury?
What is the consequence of opening the mitochondrial permeability transition pore (MPTP)?
What is the consequence of opening the mitochondrial permeability transition pore (MPTP)?
How does mitochondrial damage contribute to reactive oxygen species (ROS)?
How does mitochondrial damage contribute to reactive oxygen species (ROS)?
How does mitochondrial injury trigger apoptosis?
How does mitochondrial injury trigger apoptosis?
Which of the following is NOT a source of intracellular calcium accumulation?
Which of the following is NOT a source of intracellular calcium accumulation?
What two intracellular organelles are responsible for releasing stored calcium?
What two intracellular organelles are responsible for releasing stored calcium?
The opening of the mitochondrial permeability transition pore (MPTP) leads to ATP depletion, which in turn results in the activation of which enzyme types that contribute to cell injury?
The opening of the mitochondrial permeability transition pore (MPTP) leads to ATP depletion, which in turn results in the activation of which enzyme types that contribute to cell injury?
Match the enzymes to its contribution to cellular damage
Match the enzymes to its contribution to cellular damage
Which of the following is NOT one of the three major forms of damage caused by calcium accumulation?
Which of the following is NOT one of the three major forms of damage caused by calcium accumulation?
When are ROS normally produced in the body?
When are ROS normally produced in the body?
What makes ROS highly reactive and damaging to cells?
What makes ROS highly reactive and damaging to cells?
Which of the following is a correct sequence of partially reduced oxygen intermediates produced in normal metabolic reactions?
Which of the following is a correct sequence of partially reduced oxygen intermediates produced in normal metabolic reactions?
Which of the following is NOT a major pathological source of ROS?
Which of the following is NOT a major pathological source of ROS?
Howl does inflammation contribute to the formation of ROS?
Howl does inflammation contribute to the formation of ROS?
Why do transition metals like iron and copper contribute to ROS formation?
Why do transition metals like iron and copper contribute to ROS formation?
How does nitric oxide (NO) contribute to reactive oxygen species production?
How does nitric oxide (NO) contribute to reactive oxygen species production?
How does radiant energy contribute to ROS?
How does radiant energy contribute to ROS?
Which of the following correctly lists the four primary mechanisms by which free radicals are removed from cells?
Which of the following correctly lists the four primary mechanisms by which free radicals are removed from cells?
Which of the following describes the spontaneous decay of reactive oxygen species (ROS)?
Which of the following describes the spontaneous decay of reactive oxygen species (ROS)?
What enzymes are responsible for removing free radicals and neutralizing ROS?
What enzymes are responsible for removing free radicals and neutralizing ROS?
Which proteins help bind and neutralize reactive metals that contribute to ROS?
Which proteins help bind and neutralize reactive metals that contribute to ROS?
What are the key antioxidants that neutralize ROS?
What are the key antioxidants that neutralize ROS?
How does reactive oxygen species (ROS) cause lipid peroxidation in membranes?
How does reactive oxygen species (ROS) cause lipid peroxidation in membranes?
The “three consequences of membrane damage” are ?
The “three consequences of membrane damage” are ?
When both proteins and DNA are damaged/overwhelmed, what does this initiate?
When both proteins and DNA are damaged/overwhelmed, what does this initiate?
Flashcards
Cell Injury
Cell Injury
Changes in a cell's normal state caused by a disruption to its stability.
Cell injury happens only inside the cell
Cell injury happens only inside the cell
False. Cell injury can also happen due to external factors like toxins or lack of oxygen.
Cell injury responses
Cell injury responses
A cell's responses to injury include adapting to the stress, deteriorating, or dying.
Irreversible cell injury
Irreversible cell injury
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