Cell Injury: Causes and Types
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Questions and Answers

What is cell injury defined as?

  • A type of reversible injury
  • A sequence of biochemical and morphologic events upon exposure to an injurious agent (correct)
  • A type of cell death
  • A type of irreversible injury
  • What is the main difference between reversible and irreversible cell injury?

  • The severity of the injurious agent
  • The duration of exposure to the injurious agent
  • The outcome of the injury, with reversible injury leading to recovery and irreversible injury leading to cell death (correct)
  • The type of morphologic changes that occur
  • What is an example of a morphologic change that can occur in reversible cell injury?

  • Mitosis
  • Cellular swelling (correct)
  • Necrosis
  • Apoptosis
  • What is the outcome of severe and prolonged exposure to an injurious agent?

    <p>Irreversible cell injury</p> Signup and view all the answers

    What is the term for the process of programmed cell death?

    <p>Apoptosis</p> Signup and view all the answers

    What is an example of an injurious agent that can cause cell injury?

    <p>Water</p> Signup and view all the answers

    What is the characteristic microscopic feature of reversible cell injury in the liver?

    <p>Fine granules in the cytoplasm</p> Signup and view all the answers

    Which of the following is a clinical feature of reversible cell injury in the kidney?

    <p>Proteinuria</p> Signup and view all the answers

    What is the fate of reversible cell injury if injurious agents persist?

    <p>Cell death</p> Signup and view all the answers

    Which of the following organs is NOT affected by reversible cell injury?

    <p>Brain</p> Signup and view all the answers

    What is the definition of reversible cell injury?

    <p>Pathological accumulation of excess neutral fat in parenchymatous cells</p> Signup and view all the answers

    What is the characteristic of cellular swelling in reversible cell injury?

    <p>Small amount of water accumulation</p> Signup and view all the answers

    Which of the following is an example of a reversible cell injury in the skin?

    <p>Allergic reaction</p> Signup and view all the answers

    What is the microscopic feature of reversible cell injury in the kidney?

    <p>Proteinuria</p> Signup and view all the answers

    What is the most common site affected by cell injury?

    <p>Liver, heart, kidney, and muscles</p> Signup and view all the answers

    What is a common cause of reversible cell injury?

    <p>Excess fat in diet</p> Signup and view all the answers

    What is the characteristic microscopic feature of irreversible cell injury?

    <p>Cytoplasmic changes</p> Signup and view all the answers

    What is the definition of cell death?

    <p>Death of a group of cells within the living body</p> Signup and view all the answers

    What is the fate of cells that have undergone irreversible cell injury?

    <p>They undergo apoptosis</p> Signup and view all the answers

    What is the type of cell injury that can precede irreversible cell injury?

    <p>Reversible cell injury</p> Signup and view all the answers

    Study Notes

    Cell Injury

    • Cell injury is a sequence of biochemical and morphologic events that occur when a cell is exposed to an injurious agent.
    • Injurious agents can cause biochemical changes and morphologic changes in the cell.

    Causes of Cell Injury

    • Injurious agents can cause cell injury, including water, fat, and other factors.

    Types of Cell Injury

    • There are two types of cell injury: reversible and irreversible.

    Reversible Cell Injury

    • Reversible cell injury is characterized by cellular swelling and fatty change.
    • Cellular swelling is further divided into cloudy swelling and hydropic swelling.
    • Fatty change is the accumulation of excess neutral fat in parenchymatous cells.
    • Reversible cell injury can affect various organs, including the liver, kidney, heart, and skin.
    • Causes of reversible cell injury include excess fat in the diet, viral hepatitis, and other factors.
    • Microscopic picture of reversible cell injury shows cellular swelling, fine granules in the cytoplasm, and large clear vacuoles.
    • Clinical picture of reversible cell injury may include proteinuria, dilatation of the heart, and other symptoms.
    • Fate of reversible cell injury is that the cell can recover if the injurious agent is removed.

    Irreversible Cell Injury

    • Irreversible cell injury is characterized by cell death.
    • Cell death can occur directly or follow reversible injury.
    • Causes of irreversible cell injury include severe injury, long duration of injurious agent, and other factors.
    • Microscopic picture of irreversible cell injury shows nuclear changes and cytoplasmic changes.
    • Fate of irreversible cell injury is that the dead cells are removed by lymphatics and other mechanisms.
    • Necrosis and Apoptosis

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    Description

    Understand the definition, causes, and types of cell injury, including reversible and irreversible cell injury. Learn about the biochemical and morphologic changes that occur in cell injury.

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