Podcast
Questions and Answers
What is cell injury defined as?
What is cell injury defined as?
- A type of reversible injury
- A sequence of biochemical and morphologic events upon exposure to an injurious agent (correct)
- A type of cell death
- A type of irreversible injury
What is the main difference between reversible and irreversible cell injury?
What is the main difference between reversible and irreversible cell injury?
- The severity of the injurious agent
- The duration of exposure to the injurious agent
- The outcome of the injury, with reversible injury leading to recovery and irreversible injury leading to cell death (correct)
- The type of morphologic changes that occur
What is an example of a morphologic change that can occur in reversible cell injury?
What is an example of a morphologic change that can occur in reversible cell injury?
- Mitosis
- Cellular swelling (correct)
- Necrosis
- Apoptosis
What is the outcome of severe and prolonged exposure to an injurious agent?
What is the outcome of severe and prolonged exposure to an injurious agent?
What is the term for the process of programmed cell death?
What is the term for the process of programmed cell death?
What is an example of an injurious agent that can cause cell injury?
What is an example of an injurious agent that can cause cell injury?
What is the characteristic microscopic feature of reversible cell injury in the liver?
What is the characteristic microscopic feature of reversible cell injury in the liver?
Which of the following is a clinical feature of reversible cell injury in the kidney?
Which of the following is a clinical feature of reversible cell injury in the kidney?
What is the fate of reversible cell injury if injurious agents persist?
What is the fate of reversible cell injury if injurious agents persist?
Which of the following organs is NOT affected by reversible cell injury?
Which of the following organs is NOT affected by reversible cell injury?
What is the definition of reversible cell injury?
What is the definition of reversible cell injury?
What is the characteristic of cellular swelling in reversible cell injury?
What is the characteristic of cellular swelling in reversible cell injury?
Which of the following is an example of a reversible cell injury in the skin?
Which of the following is an example of a reversible cell injury in the skin?
What is the microscopic feature of reversible cell injury in the kidney?
What is the microscopic feature of reversible cell injury in the kidney?
What is the most common site affected by cell injury?
What is the most common site affected by cell injury?
What is a common cause of reversible cell injury?
What is a common cause of reversible cell injury?
What is the characteristic microscopic feature of irreversible cell injury?
What is the characteristic microscopic feature of irreversible cell injury?
What is the definition of cell death?
What is the definition of cell death?
What is the fate of cells that have undergone irreversible cell injury?
What is the fate of cells that have undergone irreversible cell injury?
What is the type of cell injury that can precede irreversible cell injury?
What is the type of cell injury that can precede irreversible cell injury?
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Study Notes
Cell Injury
- Cell injury is a sequence of biochemical and morphologic events that occur when a cell is exposed to an injurious agent.
- Injurious agents can cause biochemical changes and morphologic changes in the cell.
Causes of Cell Injury
- Injurious agents can cause cell injury, including water, fat, and other factors.
Types of Cell Injury
- There are two types of cell injury: reversible and irreversible.
Reversible Cell Injury
- Reversible cell injury is characterized by cellular swelling and fatty change.
- Cellular swelling is further divided into cloudy swelling and hydropic swelling.
- Fatty change is the accumulation of excess neutral fat in parenchymatous cells.
- Reversible cell injury can affect various organs, including the liver, kidney, heart, and skin.
- Causes of reversible cell injury include excess fat in the diet, viral hepatitis, and other factors.
- Microscopic picture of reversible cell injury shows cellular swelling, fine granules in the cytoplasm, and large clear vacuoles.
- Clinical picture of reversible cell injury may include proteinuria, dilatation of the heart, and other symptoms.
- Fate of reversible cell injury is that the cell can recover if the injurious agent is removed.
Irreversible Cell Injury
- Irreversible cell injury is characterized by cell death.
- Cell death can occur directly or follow reversible injury.
- Causes of irreversible cell injury include severe injury, long duration of injurious agent, and other factors.
- Microscopic picture of irreversible cell injury shows nuclear changes and cytoplasmic changes.
- Fate of irreversible cell injury is that the dead cells are removed by lymphatics and other mechanisms.
- Necrosis and Apoptosis
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