Cell Injury and Death Sequence Quiz
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Questions and Answers

What are the early functional changes seen in cell injury?

  • Enhanced cell membrane integrity
  • Increased ATP production
  • Defects in protein synthesis (correct)
  • Decreased generation of DNA
  • Which morphological changes are associated with reversible injury?

  • Plasma membrane alterations and dilation of the endoplasmic reticulum (correct)
  • Nuclear changes of pyknosis and fragmentation
  • Extensive damage to all cellular membranes
  • Swelling of lysosomes and vacuolization of mitochondria
  • In irreversible injury, what leads to the activation of enzymes that catabolize membranes, proteins, ATP, and nucleic acids?

  • Extracellular calcium entering the cell (correct)
  • Continued loss of proteins through the plasma membrane
  • Swelling of lysosomes and vacuolization of mitochondria
  • Release of intracellular calcium from stores
  • Which type of necrosis is characteristic of hypoxic death of cells in the central nervous system?

    <p>Liquefactive necrosis</p> Signup and view all the answers

    What is a distinguishing feature of apoptosis compared to necrosis?

    <p>Fragmentation of DNA within the nucleus</p> Signup and view all the answers

    Which process involves individual cell deletion in physiological growth control and disease?

    <p>Apoptosis</p> Signup and view all the answers

    What are the characteristics of apoptotic cells?

    <p>Loss of cytoskeletal framework and DNA fragmentation</p> Signup and view all the answers

    What are the components involved in haemostasis?

    <p>Vascular Wall, Platelets, The Coagulation Cascades</p> Signup and view all the answers

    What distinguishes thrombosis from normal hemostasis?

    <p>Formation of a solid mass within the vascular system</p> Signup and view all the answers

    Which factor contributes to arterial and cardiac thrombosis by causing mechanical damage and damaging the exposed endothelium?

    <p>Stasis of blood flow</p> Signup and view all the answers

    What condition can trigger arterial thrombosis due to the pressure of the tumor against the vein?

    <p>Cancer</p> Signup and view all the answers

    Which of the following is NOT a common site for arterial thrombosis?

    <p>Renal arteries</p> Signup and view all the answers

    What is the main consequence of deep vein thrombosis (DVT) involving the propagation of the thrombus?

    <p>Embolization</p> Signup and view all the answers

    In what type of blood vessel does venous thrombosis mostly occur?

    <p>Deep veins</p> Signup and view all the answers

    What is the primary cause of venous thrombosis?

    <p>Stasis of blood flow</p> Signup and view all the answers

    What triggers arterial thrombosis in patients with prosthetic cardiac valves?

    <p>Reduced blood flow</p> Signup and view all the answers

    What is the outcome of arterial thrombosis that is frequently occlusive?

    <p>Ischemia at various sites</p> Signup and view all the answers

    In which scenario would a patient require continuous anticoagulation therapy?

    <p>Prosthetic cardiac valves implantation</p> Signup and view all the answers

    What condition can result in arterial thrombosis due to prolonged bed rest or immobilization?

    <p>Myocardial infarction</p> Signup and view all the answers

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