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Questions and Answers
What is the basic unit of structure and organization in living organisms according to the Cell Theory?
What is the basic unit of structure and organization in living organisms according to the Cell Theory?
Which of the following is a major cellular organelle responsible for energy production within the cell?
Which of the following is a major cellular organelle responsible for energy production within the cell?
What is the function of RNA in the Central Dogma of Molecular Biology?
What is the function of RNA in the Central Dogma of Molecular Biology?
Which type of cells have membrane-bound organelles and are generally larger - prokaryotic or eukaryotic?
Which type of cells have membrane-bound organelles and are generally larger - prokaryotic or eukaryotic?
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What does the cytoplasm consist of?
What does the cytoplasm consist of?
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According to the Cell Theory, how do new cells arise?
According to the Cell Theory, how do new cells arise?
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Which of the following is NOT a function of microtubules?
Which of the following is NOT a function of microtubules?
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What is the approximate diameter of a microtubule?
What is the approximate diameter of a microtubule?
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What are microtubules comprised of?
What are microtubules comprised of?
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Which of the following statements about microtubules is NOT true?
Which of the following statements about microtubules is NOT true?
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What is the primary function of microtubules during cell division?
What is the primary function of microtubules during cell division?
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What type of filaments are comprised of actin molecules assembled in two long chains twisted around each other?
What type of filaments are comprised of actin molecules assembled in two long chains twisted around each other?
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Which type of fibers help to maintain the size, shape, and integrity of the cell by acting as scaffolding?
Which type of fibers help to maintain the size, shape, and integrity of the cell by acting as scaffolding?
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What is one function of intermediate filaments in a cell?
What is one function of intermediate filaments in a cell?
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Which type of filament has a diameter of approximately 8-12 nm and is comprised of a diverse range of different materials?
Which type of filament has a diameter of approximately 8-12 nm and is comprised of a diverse range of different materials?
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In the context of cytoskeleton, what does it mean for a structure to be 'dynamic'?
In the context of cytoskeleton, what does it mean for a structure to be 'dynamic'?
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Which organelle carries a separate small genome encoding mitochondrial specific products?
Which organelle carries a separate small genome encoding mitochondrial specific products?
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What is the main function of transmembrane proteins?
What is the main function of transmembrane proteins?
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Which statement accurately describes peripheral membrane proteins?
Which statement accurately describes peripheral membrane proteins?
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What is a common feature of glycoproteins found on the extracellular side of cells?
What is a common feature of glycoproteins found on the extracellular side of cells?
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What is the main role of proteoglycans in cells?
What is the main role of proteoglycans in cells?
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How do glycoproteins contribute to 'tissue typing'?
How do glycoproteins contribute to 'tissue typing'?
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Which type of proteins specifically allow external signaling molecules to communicate information to the inside of a cell?
Which type of proteins specifically allow external signaling molecules to communicate information to the inside of a cell?
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Which of the following is NOT a major organelle in eukaryotic cells?
Which of the following is NOT a major organelle in eukaryotic cells?
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What is the primary function of the plasma membrane?
What is the primary function of the plasma membrane?
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Which of the following statements about phospholipids is correct?
Which of the following statements about phospholipids is correct?
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What is the primary function of the endomembrane system?
What is the primary function of the endomembrane system?
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Which of the following organelles is primarily responsible for breaking down and recycling cellular components?
Which of the following organelles is primarily responsible for breaking down and recycling cellular components?
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What is the primary function of membrane proteins in the plasma membrane?
What is the primary function of membrane proteins in the plasma membrane?
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What is the main function of the Golgi apparatus?
What is the main function of the Golgi apparatus?
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What is the primary function of lysosomes?
What is the primary function of lysosomes?
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Which of the following statements about mitochondria is true?
Which of the following statements about mitochondria is true?
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What is the role of the cis and trans cisternae in the Golgi apparatus?
What is the role of the cis and trans cisternae in the Golgi apparatus?
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What is the purpose of the acidic pH maintained within lysosomes?
What is the purpose of the acidic pH maintained within lysosomes?
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Which of the following statements about mitochondria is false?
Which of the following statements about mitochondria is false?
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What is the function of microfilaments in a cell?
What is the function of microfilaments in a cell?
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Which type of fibers are comprised of actin molecules assembled in two long chains twisted around each other?
Which type of fibers are comprised of actin molecules assembled in two long chains twisted around each other?
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What does the term 'dynamic' mean in the context of microfilaments?
What does the term 'dynamic' mean in the context of microfilaments?
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Which organelle is responsible for encoding mitochondrial specific products?
Which organelle is responsible for encoding mitochondrial specific products?
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In terms of size, which type of fibers are the largest in the cytoskeleton?
In terms of size, which type of fibers are the largest in the cytoskeleton?
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How is the membrane structure described in the text?
How is the membrane structure described in the text?
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What is the main function of nucleolus in the nucleus?
What is the main function of nucleolus in the nucleus?
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How does DNA fit within a cell according to the text?
How does DNA fit within a cell according to the text?
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What regulates the movement of substances in and out of the nucleus?
What regulates the movement of substances in and out of the nucleus?
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What happens to chromatin as a cell prepares for division?
What happens to chromatin as a cell prepares for division?
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What is the function of nucleosomes in DNA organization?
What is the function of nucleosomes in DNA organization?
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Study Notes
Plasma Membrane
- The plasma membrane is a selectively permeable barrier controlling the passage of substances in and out of the cell
- It is a double layer of phospholipids with embedded proteins, providing a physical barrier separating the inside and outside of the cell
- Phospholipids have a hydrophobic region and hydrophilic polar heads, arranged in a double layer with their tails facing each other
- Plasma membrane proteins mediate the movement of hydrophilic substances and are often amphipathic, having both hydrophilic and hydrophobic regions
- Integral proteins are embedded (partially or fully) into the membrane
Transmembrane Proteins
- Transmembrane proteins are integral membrane proteins that fully span the entire membrane, contacting both extracellular and cytoplasmic areas
- They carry out various functions, such as:
- Channels and transporters, which can be general or selective, gated or not
- Carrying out chemical reactions, either alone or as part of a team of enzymes
- Acting as receptors for external signaling molecules
Cellular Organelles
- Major organelles include:
- Nucleus
- Endoplasmic Reticulum (smooth and rough)
- Golgi apparatus
- Lysosomes
- Mitochondria
- Ribosomes
- The endomembrane system includes the plasma membrane, along with the above organelles, working together to package, label, and ship molecules
Golgi Apparatus
- The Golgi apparatus is a series of flattened sacs or cisternae that contain enzymes of different functions
- Proteins move from the cis to trans side of the Golgi, maturing at the exit cisternae, and then travel to their destination
- Modifications occur within each sac, including the formation of glycoproteins, glycolipids, and lipoproteins
Lysosomes
- Lysosomes contain powerful digestive enzymes and are formed from the Golgi membrane
- They have a membrane that pumps H+ ions to maintain an acidic pH, protecting the rest of the cell from digestion
- Lysosomes are responsible for the digestion of:
- Substances that enter the cell
- Cell components, such as organelles (autophagy)
- Entire cells (autolysis)
Mitochondria
- Mitochondria are responsible for generating ATP through cellular respiration
- They are made up of an outer mitochondrial membrane, an inner mitochondrial membrane with folds called cristae, and a fluid-filled interior cavity called the mitochondrial matrix
- Mitochondria have a separate small genome encoding mitochondrial-specific products
- The number of mitochondria present in a cell is directly related to the amount of energy required by the cell
Cytoskeleton
- The cytoskeleton is a structural support system of the cell, providing shape, size, and integrity
- It is composed of three types of fibers:
- Microfilaments (diameter: ~7 nm, composed of actin molecules)
- Intermediate filaments (diameter: 8-12 nm, composed of diverse materials)
- Microtubules (diameter: 25 nm, composed of tubulin dimers)
- The cytoskeleton acts as scaffolding across the cell and is involved in intracellular transportation and cell movement
Nucleus
- The nucleus is the largest distinct structure inside the cell, enclosed by a double lipid bilayer called the nuclear envelope
- It is continuous with the rough Endoplasmic Reticulum and has nuclear pores that regulate the movement of substances in and out
- The nucleus contains DNA, which is wrapped around histones to form nucleosomes, and is responsible for:
- Housing and protecting DNA
- Making RNA and assembling ribosomes
- Regulating the movement of substances in and out of the nucleus
Cell Theory
- All living organisms are composed of one or more cells
- The cell is the basic unit of structure and organization
- All cells arise only from pre-existing cells
- Universal similarities between cells include:
- DNA as the heritable material
- RNA as a messenger
- Proteins as the workers
- ATP as an energy source
Prokaryote vs. Eukaryote Cells
- Prokaryote cells lack a membrane-bound nucleus and are typically smaller than eukaryote cells
- Eukaryote cells have membrane-bound organelles and are generally larger than prokaryote cells
- Both types of cells have plasma membranes, cytosol, DNA, RNA, proteins, and ribosomes
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Description
Test your knowledge on the relationship between cell energy, mitochondrial functions, and cytoskeleton components. Learn about the ATP production in relation to cell energy needs, the key role of mitochondria in carrying a separate genome, and the structural support provided by the cytoskeleton in cells.