Cell Cycle Phases and Regulation
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Questions and Answers

What occurs during the S phase of the cell cycle?

  • Apoptosis
  • Cell division
  • Protein synthesis
  • DNA replication (correct)
  • What is the role of CDK dependent kinases in the cell cycle?

  • To inhibit cell division
  • To activate cyclin
  • To phosphorylate targets (correct)
  • To degrade proteins
  • What is the function of Ubiquitination in the cell cycle?

  • To phosphorylate targets
  • To inhibit cell division
  • To degrade proteins (correct)
  • To activate protein synthesis
  • During which phase of the cell cycle does protein activation occur?

    <p>G1 phase (D)</p> Signup and view all the answers

    What is the role of Cyclin in the cell cycle?

    <p>To activate CDK dependent kinases (D)</p> Signup and view all the answers

    What is the outcome of E-CDK2 inhibition?

    <p>Cell division is inhibited (B)</p> Signup and view all the answers

    During which phase of the cell cycle does transcription activation occur?

    <p>G1 phase (B)</p> Signup and view all the answers

    What is the outcome of API transcription and degradation?

    <p>Protein levels decrease (C)</p> Signup and view all the answers

    What is the primary function of Polyubiquitination in the cell cycle?

    <p>To mark Cyclin for degradation (A)</p> Signup and view all the answers

    What is the result of APC/C-mediated degradation of Securin?

    <p>Release of cohesin complex (C)</p> Signup and view all the answers

    During which phase of the cell cycle is Cyclin-CDK 62 first transcribed?

    <p>S phase (C)</p> Signup and view all the answers

    What is the role of SCF in the cell cycle?

    <p>To target inhibitors of START for degradation (D)</p> Signup and view all the answers

    What is the consequence of CDK phosphorylation during the cell cycle?

    <p>Triggering of the Metaphase-Anaphase transition (A)</p> Signup and view all the answers

    What is the function of APC/C during the cell cycle?

    <p>To target Cyclin for degradation (D)</p> Signup and view all the answers

    What is the result of CDK inhibition during the cell cycle?

    <p>Inhibition of the G2-M transition (D)</p> Signup and view all the answers

    What is the role of the cohesin complex during the cell cycle?

    <p>To hold sister chromatids together (D)</p> Signup and view all the answers

    What is the primary function of the Nuclear Lamina in the cell?

    <p>To provide a structural support and sustain the nuclear membrane (C)</p> Signup and view all the answers

    Why does CDK phosphorylate Lamin A only during mitotic prophase?

    <p>Because the substrate specificity of CDK changes during mitotic prophase (D)</p> Signup and view all the answers

    What is the role of Cyclin in the regulation of CDK activity?

    <p>To activate CDK activity by providing a binding site (D)</p> Signup and view all the answers

    What is the mechanism by which CDK activity is regulated?

    <p>Through the orylation/de-phosphorylation of CDK (B)</p> Signup and view all the answers

    What is the result of CDK phosphorylating Lamin A during mitotic prophase?

    <p>The inactivation of Lamin A (C)</p> Signup and view all the answers

    What is the characteristic of CDK substrate recognition?

    <p>CDK recognizes different substrates through different Cyclin types (B)</p> Signup and view all the answers

    What is the fate of Cyclin during certain periods of the cell cycle?

    <p>It is rapidly degraded (C)</p> Signup and view all the answers

    What is the role of CAK in the regulation of CDK activity?

    <p>It phosphorylates CDK to activate it (C)</p> Signup and view all the answers

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