Cell-Cell Junctions in Medical Biology
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Questions and Answers

Where are tight junctions typically located in small intestinal epithelial cells?

  • At the basal part of the cells
  • At the apical part of the cells (correct)
  • Between the microvilli and the nucleus
  • At the lateral part of the cells

    • What is the main function of tight junctions?

  • To separate the nucleus from the cytoplasm
  • To create an impenetrable seal between the cells (correct)
  • To facilitate cell migration
  • To allow free passage of molecules and ions between cells

    • What type of proteins stabilize tight junctions?

  • Actin proteins
  • Occludin proteins (correct)
  • Cadherin proteins
  • Keratin proteins

    • Which technique is used to visualize tight junctions?

    <p>Transmission electron microscopy</p> Signup and view all the answers

    What is the function of anchoring junctions?

    <p>To provide minimal adhesive strength between cells</p> Signup and view all the answers

    Where are anchoring junctions located in intestinal epithelial cells?

    <p>Below the tight junctions</p> Signup and view all the answers

    What type of cell-cell junction is involved in the interaction between white blood cells and capillary endothelial cells?

    <p>Transient junctions</p> Signup and view all the answers

    Which type of junction is responsible for holding cells together?

    <p>Anchoring junctions</p> Signup and view all the answers

    What type of protein is involved in the interaction between white blood cells and capillary endothelial cells?

    <p>All of the above</p> Signup and view all the answers

    What is the function of gap junctions?

    <p>To allow for communication between cells</p> Signup and view all the answers

    What is the name of the type of anchoring junction that is associated with intermediate filaments?

    <p>Macula adherens</p> Signup and view all the answers

    What is the term for the process of white blood cells passing through the capillary wall?

    <p>Extravasation</p> Signup and view all the answers

    What is a consequence of losing E-cadherin expression in epithelial cells?

    <p>Metastasis formation of cancers</p> Signup and view all the answers

    What type of junctions are formed by actin microfilament-associated proteins?

    <p>Zonula adherens</p> Signup and view all the answers

    What is the name of the autoimmune disease that is characterized by the formation of autoantibodies against cadherin proteins?

    <p>Pemphigus</p> Signup and view all the answers

    What is the primary function of gap junctions?

    <p>To permit direct transfer of ions and small molecules</p> Signup and view all the answers

    What is the name of the type of junction that is characterized by a tight seal between cells?

    <p>Tight junction</p> Signup and view all the answers

    What type of filaments are associated with macula adherens?

    <p>Intermediate filaments</p> Signup and view all the answers

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