Cell-Cell Junctions in Medical Biology

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18 Questions

Where are tight junctions typically located in small intestinal epithelial cells?

At the apical part of the cells

What is the main function of tight junctions?

To create an impenetrable seal between the cells

What type of proteins stabilize tight junctions?

Occludin proteins

Which technique is used to visualize tight junctions?

Transmission electron microscopy

What is the function of anchoring junctions?

To provide minimal adhesive strength between cells

Where are anchoring junctions located in intestinal epithelial cells?

Below the tight junctions

What type of cell-cell junction is involved in the interaction between white blood cells and capillary endothelial cells?

Transient junctions

Which type of junction is responsible for holding cells together?

Anchoring junctions

What type of protein is involved in the interaction between white blood cells and capillary endothelial cells?

All of the above

What is the function of gap junctions?

To allow for communication between cells

What is the name of the type of anchoring junction that is associated with intermediate filaments?

Macula adherens

What is the term for the process of white blood cells passing through the capillary wall?

Extravasation

What is a consequence of losing E-cadherin expression in epithelial cells?

Metastasis formation of cancers

What type of junctions are formed by actin microfilament-associated proteins?

Zonula adherens

What is the name of the autoimmune disease that is characterized by the formation of autoantibodies against cadherin proteins?

Pemphigus

What is the primary function of gap junctions?

To permit direct transfer of ions and small molecules

What is the name of the type of junction that is characterized by a tight seal between cells?

Tight junction

What type of filaments are associated with macula adherens?

Intermediate filaments

This quiz covers the types of cell-cell junctions, including transient, stable, occluding, anchoring, and communicating junctions. Learn about zonula occludens, zonula adherens, macula adherens, and gap junctions in medical biology.

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