Cell-Cell Junctions in Medical Biology

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Questions and Answers

Where are tight junctions typically located in small intestinal epithelial cells?

  • At the basal part of the cells
  • At the apical part of the cells (correct)
  • Between the microvilli and the nucleus
  • At the lateral part of the cells

What is the main function of tight junctions?

  • To separate the nucleus from the cytoplasm
  • To create an impenetrable seal between the cells (correct)
  • To facilitate cell migration
  • To allow free passage of molecules and ions between cells

What type of proteins stabilize tight junctions?

  • Actin proteins
  • Occludin proteins (correct)
  • Cadherin proteins
  • Keratin proteins

Which technique is used to visualize tight junctions?

<p>Transmission electron microscopy (C)</p> Signup and view all the answers

What is the function of anchoring junctions?

<p>To provide minimal adhesive strength between cells (D)</p> Signup and view all the answers

Where are anchoring junctions located in intestinal epithelial cells?

<p>Below the tight junctions (D)</p> Signup and view all the answers

What type of cell-cell junction is involved in the interaction between white blood cells and capillary endothelial cells?

<p>Transient junctions (C)</p> Signup and view all the answers

Which type of junction is responsible for holding cells together?

<p>Anchoring junctions (D)</p> Signup and view all the answers

What type of protein is involved in the interaction between white blood cells and capillary endothelial cells?

<p>All of the above (D)</p> Signup and view all the answers

What is the function of gap junctions?

<p>To allow for communication between cells (B)</p> Signup and view all the answers

What is the name of the type of anchoring junction that is associated with intermediate filaments?

<p>Macula adherens (D)</p> Signup and view all the answers

What is the term for the process of white blood cells passing through the capillary wall?

<p>Extravasation (A)</p> Signup and view all the answers

What is a consequence of losing E-cadherin expression in epithelial cells?

<p>Metastasis formation of cancers (A)</p> Signup and view all the answers

What type of junctions are formed by actin microfilament-associated proteins?

<p>Zonula adherens (C)</p> Signup and view all the answers

What is the name of the autoimmune disease that is characterized by the formation of autoantibodies against cadherin proteins?

<p>Pemphigus (C)</p> Signup and view all the answers

What is the primary function of gap junctions?

<p>To permit direct transfer of ions and small molecules (C)</p> Signup and view all the answers

What is the name of the type of junction that is characterized by a tight seal between cells?

<p>Tight junction (B)</p> Signup and view all the answers

What type of filaments are associated with macula adherens?

<p>Intermediate filaments (D)</p> Signup and view all the answers

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