Podcast
Questions and Answers
Which family of integral membrane protein mediates cell-cell adhesion by binding to carbohydrates on glycoproteins?
Which family of integral membrane protein mediates cell-cell adhesion by binding to carbohydrates on glycoproteins?
Which type of cell-cell junctions are found in epithelia?
Which type of cell-cell junctions are found in epithelia?
Which signaling system occurs when a cell produces and responds to its own signaling molecules?
Which signaling system occurs when a cell produces and responds to its own signaling molecules?
Which family of integral membrane protein mediates adhesion between nonimmune cells?
Which family of integral membrane protein mediates adhesion between nonimmune cells?
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Which type of cell-cell junctions seal the extracellular space and make epithelial layers impermeable?
Which type of cell-cell junctions seal the extracellular space and make epithelial layers impermeable?
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Which signaling system occurs when a cell produces signaling molecules that affect nearby cells?
Which signaling system occurs when a cell produces signaling molecules that affect nearby cells?
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What converts information carried by extracellular messenger molecules into cellular responses?
What converts information carried by extracellular messenger molecules into cellular responses?
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Study Notes
- Four families of integral membrane protein mediate cell-cell adhesion: selectins, immunoglobulin superfamily, integrin family, and cadherins.
- Selectins bind to carbohydrates on glycoproteins from other cells and have a small cytoplasmic segment, a single membrane spanning domain, and a large extracellular portion.
- Immunoglobulin superfamily mediates adhesion between nonimmune cells and the Ig domains of one CAM binds to opposing CAM.
- Cadherins mediate cell-cell adhesion, and each type mediates cell-type specific adhesion and typically join cells of similar type to one another.
- Adherens junctions and desmosomes are types of cell-cell junctions found in epithelia.
- Tight junctions seal the extracellular space and make epithelial layers impermeable.
- Gap junctions permit intercellular communication through molecular “pipelines” between cells.
- Extracellular signals can take several forms, including small chemicals and mechanical stimuli.
- Three types of signaling systems are autocrine, paracrine, and endocrine.
- Signaling pathways consist of a series of proteins that ultimately alter cell activity, and signal transduction converts information carried by extracellular messenger molecules into cellular responses.
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Description
Test your knowledge of cell-cell adhesion and signaling systems with this informative quiz! Learn about the four families of integral membrane proteins that mediate cell-cell adhesion, as well as different types of cell-cell junctions found in epithelia. Explore the various types of extracellular signals and signaling pathways involved in cellular responses, and gain a deeper understanding of autocrine, paracrine, and endocrine signaling systems. Sharpen your skills with this quiz, and become an expert in the fascinating world of