Cell Biology Quiz: Membranes and Adaptations
41 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary function of the cell membrane?

  • Synthesizes proteins
  • Generates energy for the cell
  • Controls the movement of substances into and out of the cell (correct)
  • Provides structural support to the cell
  • Which of the following is NOT a type of cell adaptation?

  • Hypertrophy
  • Necrosis (correct)
  • Atrophy
  • Metaplasia
  • What is the primary function of the nucleus?

  • Provides structural support
  • Synthesizes lipids
  • Contains the cell's genetic material (correct)
  • Generates energy for the cell
  • Which of the following is a common cause of cell injury?

    <p>Nutrient deprivation (C)</p> Signup and view all the answers

    What is the difference between apoptosis and necrosis?

    <p>Apoptosis is a programmed cell death, while necrosis is a result of injury (C)</p> Signup and view all the answers

    Which of the following is NOT a cause of hypoxic injury?

    <p>Hyperplasia (A)</p> Signup and view all the answers

    What is the primary consequence of decreased oxygen delivery to cells?

    <p>Increased anaerobic metabolism (B)</p> Signup and view all the answers

    Which of the following is a characteristic of anaerobic metabolism in hypoxic cells?

    <p>Production of lactic acid as a byproduct (B)</p> Signup and view all the answers

    What is the term for an increase in the size of a cell, often associated with an increase in the amount of actin and myosin?

    <p>Hypertrophy (C)</p> Signup and view all the answers

    What is the term for the transformation of one cell type into another, which can occur as a response to chronic irritation or injury?

    <p>Metaplasia (A)</p> Signup and view all the answers

    Which of the following cellular adaptations is characterized by a reversible replacement of one mature cell type by another?

    <p>Metaplasia (C)</p> Signup and view all the answers

    Which of the following cellular adaptations is often associated with an increase in the size of cells due to increased workload?

    <p>Hypertrophy (D)</p> Signup and view all the answers

    Which cellular adaptation is characterized by an abnormal change in the size, shape, and organization of mature cells, often associated with an increased risk of cancer development?

    <p>Dysplasia (C)</p> Signup and view all the answers

    Which of the following cellular adaptations involves a decrease in the size of cells, often due to reduced workload or inadequate nutrition?

    <p>Atrophy (A)</p> Signup and view all the answers

    What is the underlying mechanism behind hormonal hyperplasia?

    <p>Hormonal stimulation (C)</p> Signup and view all the answers

    Which type of cellular adaptation is considered a protective mechanism, replacing fragile epithelium with more resilient cell types?

    <p>Metaplasia (A)</p> Signup and view all the answers

    Which of the following is NOT a possible cause of atrophy?

    <p>Increased workload (C)</p> Signup and view all the answers

    What is the characteristic feature of dysplasia that distinguishes it from other adaptive changes?

    <p>Abnormal changes in cell size, shape, and organization (B)</p> Signup and view all the answers

    Which of the following scenarios would be most likely to lead to hypertrophy of skeletal muscle?

    <p>Regular weightlifting training (B)</p> Signup and view all the answers

    Which cellular adaptation could be described as a compensatory response to tissue damage, helping to replace lost cells and regenerate tissues?

    <p>Hyperplasia (B)</p> Signup and view all the answers

    What is a characteristic of free radicals that makes them reactive?

    <p>They contain one or more unpaired electrons. (D)</p> Signup and view all the answers

    How can free radicals damage DNA?

    <p>All of the above. (D)</p> Signup and view all the answers

    Which of the following is NOT a consequence of free radical damage to lipids and proteins?

    <p>Increased cell signaling efficiency. (A)</p> Signup and view all the answers

    Which of the following is NOT an example of a disease linked to free radical damage?

    <p>Diabetes. (B)</p> Signup and view all the answers

    Why are antioxidants important for preventing free radical damage?

    <p>They donate electrons to free radicals, stabilizing them. (D)</p> Signup and view all the answers

    Which of the following is NOT a good source of antioxidants?

    <p>Processed meats. (A)</p> Signup and view all the answers

    Based on the information provided, how might free radicals contribute to the development of cardiovascular disease?

    <p>By damaging blood vessels, leading to atherosclerosis. (D)</p> Signup and view all the answers

    What is the primary way that free radicals cause cell injury?

    <p>By disrupting the function of important cellular molecules. (B)</p> Signup and view all the answers

    Which of the following clinical examples is NOT directly related to apoptosis?

    <p>Wet Gangrene (B)</p> Signup and view all the answers

    What is a major difference between apoptosis and necrosis?

    <p>Necrosis triggers an inflammatory response, while apoptosis does not (B)</p> Signup and view all the answers

    How does wet gangrene differ from dry gangrene?

    <p>Wet gangrene is characterized by tissue liquefaction, while dry gangrene involves tissue mummification (C)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of apoptosis?

    <p>Inflammation (C)</p> Signup and view all the answers

    Which of the following scenarios is MOST likely to result in wet gangrene?

    <p>Crush injury to a limb with compromised blood supply (D)</p> Signup and view all the answers

    What is the direct consequence of decreased ATP production in a cell?

    <p>Failure of the Na+/K+ pump (C)</p> Signup and view all the answers

    What is the key factor responsible for cellular and organelle swelling during decreased ATP production?

    <p>Accumulation of Na+ in the cell (D)</p> Signup and view all the answers

    Which of the following consequences directly results from the failure of the Ca++ pump in a cell?

    <p>Accumulation of Ca++ in the cell (B)</p> Signup and view all the answers

    Which of these events is a direct consequence of the accumulation of lactic acid during anaerobic metabolism?

    <p>Lysosomal membrane breakdown (C)</p> Signup and view all the answers

    What is the main consequence of the release of lysosomal hydrolytic enzymes within a cell?

    <p>Autodigestion of the cell (D)</p> Signup and view all the answers

    What is the primary mechanism by which reperfusion injury occurs?

    <p>Formation of free radical molecules (D)</p> Signup and view all the answers

    What is the source of the xanthine oxidase enzyme involved in free radical formation during reperfusion?

    <p>Hypoxic cells (A)</p> Signup and view all the answers

    What is the direct consequence of free radical formation during reperfusion?

    <p>Damage to cell components (B)</p> Signup and view all the answers

    Flashcards

    Cell Adaptations

    Changes in cell structure or function in response to stress.

    Cell Injury

    Damage to a cell that impairs its function but may be reversible.

    Cell Death

    Permanent loss of cell function and integrity, can be due to injury or stress.

    Concept Overview

    A general summary of key concepts related to cell function changes.

    Signup and view all the flashcards

    Schematic Diagram of a Cell

    A visual representation illustrating the structure and components of a cell.

    Signup and view all the flashcards

    Hyperplasia

    An increase in the number of cells in a tissue or organ.

    Signup and view all the flashcards

    Muscle Hypertrophy

    Increase in the size of muscle cells due to exercise or stress.

    Signup and view all the flashcards

    Hypoxic Injury

    Damage caused by insufficient oxygen delivery to tissues.

    Signup and view all the flashcards

    Anaerobic Metabolism

    Energy production without oxygen, resulting in less ATP.

    Signup and view all the flashcards

    ATP Production

    The formation of adenosine triphosphate, the energy currency of the cell.

    Signup and view all the flashcards

    Lysosomes

    Organelles that contain enzymes for digestion of cellular waste.

    Signup and view all the flashcards

    Mitochondria

    Powerhouse of the cell; produces ATP through respiration.

    Signup and view all the flashcards

    Ribosomes

    Cellular structures that synthesize proteins from amino acids.

    Signup and view all the flashcards

    Atrophy

    Decrease or shrinkage in the size of cells from disuse.

    Signup and view all the flashcards

    Hypertrophy

    Increase in the size of cells, often due to increased workload.

    Signup and view all the flashcards

    Metaplasia

    Reversible replacement of one mature cell type by another.

    Signup and view all the flashcards

    Dysplasia

    Abnormal changes in cell size, shape, and organization.

    Signup and view all the flashcards

    Compensatory Hyperplasia

    Increase in cell numbers to compensate for loss or injury.

    Signup and view all the flashcards

    Hormonal Hyperplasia

    Increase in cell numbers due to hormonal stimulation.

    Signup and view all the flashcards

    Decreased ATP Production

    Reduction in the synthesis of adenosine triphosphate (ATP), the energy currency of the cell.

    Signup and view all the flashcards

    Na+/K+ Pump Failure

    Malfunction of the sodium-potassium pump, leading to disrupted ion balance across the membrane.

    Signup and view all the flashcards

    Na+ Accumulation in Cell

    Build-up of sodium ions inside the cell due to pump failure, causing swelling.

    Signup and view all the flashcards

    Cell Swelling

    Increase in cell volume due to excess water following sodium accumulation.

    Signup and view all the flashcards

    Ca++ Pump Failure

    Failure of the calcium pump, resulting in increased calcium levels inside the cell.

    Signup and view all the flashcards

    Lactic Acid Formation

    Production of lactic acid due to anaerobic metabolism when oxygen is insufficient.

    Signup and view all the flashcards

    Hydrolytic Enzymes Release

    Release of enzymes from lysosomes that can digest cellular components, leading to autodigestion.

    Signup and view all the flashcards

    Reperfusion Injury

    Damage caused when blood supply returns to tissue after a period of hypoxia, potentially forming free radicals.

    Signup and view all the flashcards

    Gangrene

    Death of a large area of tissue due to severe hypoxia.

    Signup and view all the flashcards

    Wet Gangrene

    Gangrene caused by bacterial invasion in hypoxic tissue.

    Signup and view all the flashcards

    Dry Gangrene

    Gangrene resulting from ischemia, without bacterial infection.

    Signup and view all the flashcards

    Apoptosis

    Programmed cell death initiated by internal mechanisms without inflammation.

    Signup and view all the flashcards

    Apoptosis Examples

    Apoptosis occurs during embryonic development and in cancer treatment.

    Signup and view all the flashcards

    Free Radicals

    Highly reactive molecules with unpaired electrons causing cell damage.

    Signup and view all the flashcards

    DNA Damage from Free Radicals

    Free radicals can break DNA strands, causing mutations.

    Signup and view all the flashcards

    Lipid and Protein Damage

    Free radicals damage cell membranes and structural proteins.

    Signup and view all the flashcards

    Antioxidants

    Molecules that neutralize free radicals, preventing cell damage.

    Signup and view all the flashcards

    Sources of Antioxidants

    Vitamins and foods that provide antioxidants include fruits and nuts.

    Signup and view all the flashcards

    Necrosis

    Cell death due to injury characterized by swelling and membrane loss.

    Signup and view all the flashcards

    Study Notes

    Alterations of Cell Function

    • NUR3110 course
    • Topics: Cell injury, cell death, and alterations in cellular function.

    Concept Overview

    •  This section provides a general introduction to the topic.

    Review of Cell Structure

    •  A diagram showing a schematic of a cell with labeled components such as mitochondria, plasma membrane, lysosomes, nucleus, ribosomes on the rough endoplasmic reticulum, sodium-potassium pump and calcium pump.

    Review - ATP Production

    • A diagram relating to ATP production in the cell is presented. Oxygen (O2), and glucose (G) are shown as inputs to a process in the cell, and ATP as an output

    Review - ATP Utilization

    •  Multiple diagrams showing the utilization of ATP in various cellular processes, including sodium-potassium pump function, calcium pump function, cell structure and function, lipid transport, and secretion.

    Review of Normal ATP Production

    •  A detailed diagram illustrating the Citric acid cycle (Krebs cycle).
    •  The Krebs cycle is a crucial part of cellular respiration for ATP generation.
    • Key components and reactions involved in the Citric acid cycle are referenced, as well as related molecules.

    Review of Normal ATP Production (cont.)

    • Detailed depictions of processes relating to the electron transport chain for the continued creation of ATP. This is a key part of cellular respiration.

    Cellular Adaptation

    •  Describes cell adaptations like atrophy, hypertrophy, hyperplasia, metaplasia, and dysplasia. Each is described individually below.

    Atrophy

    •   A decrease or shrinkage in the size of cells.
    • Examples, such as disuse atrophy and adrenal gland atrophy, are shown.

    Hypertrophy

    • An increase in the size of cells.
    • Examples, such as skeletal muscle hypertrophy and cardiac muscle hypertrophy, are depicted.

    Hyperplasia

    • An increase in the number of cells.
    • Examples of types of hyperplasia include compensatory and hormonal hyperplasia.
    • Compensatory hyperplasia is illustrated with liver regeneration following a transplant operation.
    • Hormonal changes are illustrated with puberty-linked changes in breast growth.
    • Pathologic hyperplasia is illustrated, with benign prostatic hyperplasia. A diagram showing normal prostate compared with an enlarged prostate is included.

    Metaplasia

    • The reversible replacement of one mature cell type by another.
    • Diagrams demonstrate normal vs metaplasia and bronchial metaplasia.

    Dysplasia

    • Abnormal changes in the size, shape, and organization of mature cells
    • Different stages of dysplasia are shown diagramatically - mild, moderate and severe or carcinoma in situ.

    Test Your Understanding (iClicker Questions)

    •  Multiple-choice questions regarding cellular adaptation concepts and examples are presented.

    Hypoxic Injury

    •  Description of mechanisms by which the delivery of oxygen to tissues may be prevented.
    • Causes of hypoxic injury such as hypoxemia (low oxygen in blood) and ischemia (reduced blood flow).
    • Consequences of hypoxic injury, including decreased ATP production, failure of Na+/K+ pump, and the accumulation of Na+ and Ca²⁺ in the cell.
    • A variety of diagrams illustrates consequences of cellular injury including anaerobic metabolism, decreased protein synthesis, increased lactic acid, lysosomal degradation and decreased functional protein availability.

    Reperfusion Injury

    •  The implications of introducing oxygen to hypoxic tissue, and the possibility of further damage to the cell following oxygen restoration. A brief description of how oxygen is then used by cells.

    Free Radical Injury

    •  Overview of free radicals, and impacts on cells including DNA damage, and damage to plasma membranes, enzymes and structural proteins.
    •  Free radicals are described as having unpaired electrons.
    •  The clinical relevance is highlighted by illustrations of cancer and cardiovascular disease.
    • This section describes how free radicals react with other components in the cell.

    Inactivation of Free Radicals

    •  Mechanisms used to reduce the potential for harm including antioxidants with illustrations, and examples of antioxidant-rich foods.

    Cell Death - Overview

    •  Two types of cell death: necrosis and apoptosis.
    • Necrosis is classified as cell death due to injury, while apoptosis is "programmed" cell death.

    Necrosis

    •  Loss of plasma membrane structure leads to swelling of organelles.
    • Mitochondria dysfunction leads to cell death.
    • Necrosis looks different depending on the tissue.

    Gangrene (Gangrenous Necrosis)

    •  Extensive cell death from severe hypoxic injury
    •  Types of gangrene include wet/moist (bacterial infection) and dry gangrene.

    Apoptosis

    •  A process of controlled cell death initiated by internal mechanisms.
    •  Unlike necrosis, an inflammatory response is not triggered.

    Apoptosis Clinical Examples

    • Illustrates how apoptosis functions in embryonic development and cancer scenarios.

    Quizzes and Study Guides

    • Information about scheduled quizzes and a study guide in the Canvas online learning platform.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Alt Cell Fcn Lecture Slides PDF

    Description

    Test your knowledge on cell biology concepts, particularly focusing on cell membranes, adaptations, and types of cell injury. This quiz will cover essential functions of cell components and the mechanisms behind cellular changes. Perfect for students studying biology or advancing their understanding of cellular processes.

    More Like This

    Cell Membrane Flashcards
    12 questions

    Cell Membrane Flashcards

    EasygoingAgate6318 avatar
    EasygoingAgate6318
    Cell Membrane and Membrane Transport Quiz
    18 questions
    Cell Membrane and Organelles Flashcards
    30 questions
    Use Quizgecko on...
    Browser
    Browser