Cell Biology: Plasma Membrane Structure
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Questions and Answers

What is the primary structure of the plasma membrane as described by the Fluid Mosaic Model?

  • A bilayer of phospholipids with embedded proteins (correct)
  • A rigid structure of carbohydrates
  • A single layer of cholesterol molecules
  • A continuous thick layer of proteins
  • Which component of the plasma membrane is present only on the outer surface?

  • Carbohydrate groups (correct)
  • Phospholipids
  • Transmembrane proteins
  • Cholesterol
  • What characteristic of phospholipids makes them suitable for forming a bilayer?

  • They contain cholesterol
  • They have a rigid structure
  • They are hydrophobic only
  • They are amphipathic (correct)
  • What role does cholesterol play in the plasma membrane?

    <p>It helps stabilize the membrane structure (C)</p> Signup and view all the answers

    How do small molecules generally move across the plasma membrane compared to large molecules?

    <p>Small molecules move more easily due to their size (C)</p> Signup and view all the answers

    Which statement correctly differentiates between hydrophilic and hydrophobic regions of phospholipids?

    <p>Hydrophilic regions are water-loving and face outward, hydrophobic regions are water-fearing and face inward (B)</p> Signup and view all the answers

    What kind of molecules typically require transmembrane proteins to cross the plasma membrane?

    <p>Ions and large polar molecules (A)</p> Signup and view all the answers

    What term describes the model that explains the dynamic arrangement of phospholipids and proteins in the plasma membrane?

    <p>Fluid Mosaic Model (C)</p> Signup and view all the answers

    What is the primary reason that phospholipids arrange themselves with their hydrophobic tails facing each other in an aqueous solution?

    <p>To minimize energy by avoiding contact with water (B)</p> Signup and view all the answers

    Which type of protein is integrated into the plasma membrane and contains hydrophobic regions?

    <p>Integral membrane proteins (D)</p> Signup and view all the answers

    What role does cholesterol play in membrane fluidity at low temperatures?

    <p>Increases fluidity by preventing tight packing of phospholipids (D)</p> Signup and view all the answers

    What role do carbohydrates play in plasma membranes?

    <p>They serve as distinctive cellular markers. (B)</p> Signup and view all the answers

    Which term describes the movement of water from an area of lower solute concentration to an area of higher solute concentration?

    <p>Osmosis (A)</p> Signup and view all the answers

    How do unsaturated fatty acids affect membrane fluidity compared to saturated fatty acids?

    <p>They maintain fluidity at lower temperatures. (A)</p> Signup and view all the answers

    What is the effect of cholesterol on membrane fluidity?

    <p>Cholesterol assists in maintaining fluidity across temperature changes. (A)</p> Signup and view all the answers

    What is the primary difference between osmolarity and tonicity?

    <p>Tonicity also considers permeability of the membrane to solutes (B)</p> Signup and view all the answers

    Which statement correctly describes passive transport?

    <p>Involves substances moving down their concentration gradient (C)</p> Signup and view all the answers

    What distinguishes transmembrane proteins from other integral proteins?

    <p>They span the entire membrane and are involved in transporting substances. (D)</p> Signup and view all the answers

    How do carrier proteins function in facilitated diffusion?

    <p>They assist specific molecules in crossing the membrane (C)</p> Signup and view all the answers

    What is a micelle, and when does it typically form?

    <p>A small, single-layered sphere formed from phospholipids with small tails. (B)</p> Signup and view all the answers

    What characteristic of phospholipids contributes to selective permeability?

    <p>Hydrophobic core created by the arrangement of phospholipids (A)</p> Signup and view all the answers

    What are the characteristics of peripheral membrane proteins?

    <p>They are loosely attached and do not span the membrane. (C)</p> Signup and view all the answers

    What determines whether a solution is hypertonic, isotonic, or hypotonic?

    <p>The relative solute concentrations and their effect on cell membranes (B)</p> Signup and view all the answers

    What is the primary mechanism through which facilitated diffusion occurs?

    <p>Membrane proteins aiding in transport (C)</p> Signup and view all the answers

    What is the primary function of channel proteins in the plasma membrane?

    <p>Facilitating the diffusion of polar and charged molecules (B)</p> Signup and view all the answers

    Which statement about carrier proteins is true?

    <p>They facilitate transport by changing shape to move target molecules. (D)</p> Signup and view all the answers

    What is the role of the sodium-potassium pump in active transport?

    <p>To maintain proper sodium and potassium concentrations (C)</p> Signup and view all the answers

    What triggers the sodium-potassium pump to change shape after sodium ions are bound?

    <p>The phosphorylation of the pump by ATP (B)</p> Signup and view all the answers

    What does secondary active transport involve?

    <p>Cotransport of molecules along with another molecule moving down its gradient (C)</p> Signup and view all the answers

    How does the sodium-potassium pump contribute to generating voltage across the cell membrane?

    <p>By actively transporting three sodium ions out and two potassium ions into the cell (A)</p> Signup and view all the answers

    Which of the following correctly describes facilitated diffusion?

    <p>It involves channel proteins and carrier proteins for passive transport. (C)</p> Signup and view all the answers

    What happens to the sodium-potassium pump after it binds to potassium ions?

    <p>It resets to its original shape, opening towards the cell interior. (D)</p> Signup and view all the answers

    What occurs when the sodium-potassium pump loses affinity for potassium ions?

    <p>Two potassium ions are released into the cytoplasm. (A)</p> Signup and view all the answers

    How does the sodium-potassium pump establish negative membrane potential?

    <p>By moving 3 Na out and only 2 K in. (B)</p> Signup and view all the answers

    What role does secondary active transport play in cellular functions?

    <p>It couples the movement of sodium ions with other substances against their gradients. (B)</p> Signup and view all the answers

    What is involved in the process of endocytosis?

    <p>Enclosing particles in vesicles made from the plasma membrane. (C)</p> Signup and view all the answers

    What is a key feature of the sodium-potassium pump’s action?

    <p>It establishes a concentration gradient for sodium ions. (C)</p> Signup and view all the answers

    Which of the following best describes phagocytosis?

    <p>Enclosing large particles in vesicles. (D)</p> Signup and view all the answers

    What happens to potassium ions when their concentration gradient creates a large enough voltage across the membrane?

    <p>The voltage counterbalances the potassium’s concentration gradient. (D)</p> Signup and view all the answers

    What is the main function of the carrier protein in secondary active transport?

    <p>To facilitate the transport of one substance uphill while another moves downhill. (A)</p> Signup and view all the answers

    What is the primary function of lysosomes in the context of phagocytosis?

    <p>To break down engulfed particles (D)</p> Signup and view all the answers

    Which type of endocytosis involves the uptake of large particles such as cells or debris?

    <p>Phagocytosis (D)</p> Signup and view all the answers

    How do receptor proteins function in receptor-mediated endocytosis?

    <p>By binding to specific target molecules and triggering endocytosis (C)</p> Signup and view all the answers

    What distinguishes pinocytosis from phagocytosis?

    <p>Pinocytosis is often termed 'cell drinking' and involves the uptake of small amounts of extracellular fluid. (C)</p> Signup and view all the answers

    What is the main role of exocytosis?

    <p>To remove waste and release substances from the cell (D)</p> Signup and view all the answers

    Which statement accurately describes receptor-mediated endocytosis?

    <p>It allows for the uptake of molecules that are present in low concentrations. (B)</p> Signup and view all the answers

    What happens to the food vacuole after it engulfs a target particle?

    <p>It fuses with the lysosome for further processing. (D)</p> Signup and view all the answers

    What is a potential downside of receptor-mediated endocytosis?

    <p>It can inadvertently allow harmful particles, such as viruses, to enter the cell. (C)</p> Signup and view all the answers

    Flashcards

    What is the fluid mosaic model?

    The fluid mosaic model describes the structure of the plasma membrane as a dynamic and flexible arrangement of phospholipids, cholesterol, and proteins that can move freely within the membrane.

    What are phospholipids and what's their role in the plasma membrane?

    Phospholipids are the primary structural component of the plasma membrane. They have a hydrophilic head that interacts with water and a hydrophobic tail that repels water, creating a bilayer structure with the tails facing inwards.

    What is the role of cholesterol in the plasma membrane?

    Cholesterol is another lipid found interspersed within the phospholipid bilayer. It helps regulate membrane fluidity by preventing the phospholipids from packing too tightly at low temperatures or becoming too loose at high temperatures.

    What are membrane proteins and what are their functions?

    Membrane proteins are embedded within the plasma membrane and play a variety of roles, including transporting molecules across the membrane, acting as receptors for signaling molecules, and providing structural support.

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    What are carbohydrate groups in the plasma membrane?

    Carbohydrate groups are attached to the outer surface of the plasma membrane, either to proteins (forming glycoproteins) or lipids (forming glycolipids). These groups can be involved in cell recognition and signaling.

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    What makes the head of a phospholipid hydrophilic?

    Hydrophilic regions of phospholipids, such as the phosphate group and the attached R group, are attracted to water and face outwards towards the aqueous environment both inside and outside the cell.

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    What makes the tail of a phospholipid hydrophobic?

    Hydrophobic regions of phospholipids are the fatty acid tails, which are repelled by water and buried inside the membrane core, away from the aqueous environment.

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    How do phospholipids form a bilayer?

    Due to their amphipathic nature, phospholipids spontaneously form a bilayer in aqueous environments. The hydrophobic tails face inwards, shielding themselves from water, while the hydrophilic heads interact with the water.

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    Phospholipid Bilayer

    The tendency of phospholipids in water or aqueous solutions to arrange themselves with hydrophobic tails facing inwards and hydrophilic heads facing outwards.

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    Micelle

    A small, single-layered sphere formed by phospholipids with small tails, where the hydrophobic tails face inwards and the hydrophilic heads face outwards.

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    Liposome

    A hollow droplet of bilayer membrane formed by phospholipids with bulkier tails, where the hydrophobic tails face inwards and the hydrophilic heads face outwards.

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    Integral membrane proteins

    Proteins embedded within the plasma membrane, usually with hydrophobic regions anchoring them to the hydrophobic core.

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    Peripheral membrane proteins

    Proteins found on the outer and inner surfaces of membranes, loosely attached to integral proteins or phospholipids.

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    Transmembrane proteins

    Integral membrane proteins that span the entire membrane, with parts exposed to both the outer and inner regions. They can act as channels for ions or transport molecules.

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    Membrane carbohydrates

    Carbohydrates attached to proteins or lipids on the outer surface of cell membranes. They act as cellular markers and play a role in cell recognition.

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    Membrane fluidity

    The ability of the cell membrane to maintain a fluid-like state, allowing movement and flexibility.

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    What's the role of cholesterol in membrane fluidity?

    Cholesterol helps keep membranes fluid at low temperatures by preventing phospholipids from packing tightly, and it helps reduce fluidity at high temperatures.

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    Define osmosis.

    The net movement of water across a semipermeable membrane from an area of lower solute concentration to an area of higher solute concentration.

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    What is osmolarity?

    The total concentration of solutes in a solution.

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    How does osmolarity affect water movement?

    A solution with a low osmolarity has fewer solute particles per unit volume. A solution with a high osmolarity has more solute particles per unit volume.

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    Define tonicity.

    The ability of an extracellular solution to make water move into or out of a cell by osmosis.

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    What is passive transport?

    The movement of a substance down its concentration gradient, meaning from an area of higher concentration to an area of lower concentration.

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    What is selective permeability?

    The ability of a membrane to allow certain substances to pass through while blocking others.

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    What is facilitated diffusion?

    Facilitated diffusion involves the movement of substances across a membrane with the assistance of membrane proteins. It's still a passive process, meaning the cell doesn't expend energy. Channels and carrier proteins are two types.

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    Sodium-Potassium Pump

    The sodium-potassium pump moves sodium ions out of the cell and potassium ions into the cell, maintaining a concentration gradient. This process requires energy and uses ATP.

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    Membrane Potential

    The movement of potassium ions out of the cell down their concentration gradient helps establish the membrane potential. This makes the inside of the cell negative relative to the outside.

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    Secondary Active Transport

    This type of transport uses the energy stored in concentration gradients created by primary active transport to move other substances across the membrane.

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    Bulk Transport

    Large particles or quantities of smaller particles are moved across the cell membrane in this process.

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    Phagocytosis

    A type of endocytosis where the cell engulfs solid particles, forming a phagosome that fuses with a lysosome for digestion.

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    Pinocytosis

    A type of endocytosis where the cell takes in fluids and dissolved substances, forming a pinosome that fuses with a lysosome for digestion.

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    Receptor Mediated Endocytosis

    A type of endocytosis where specific molecules bind to receptors on the cell surface, triggering the formation of a vesicle.

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    Exocytosis

    A process where cells release substances from the inside to the outside by fusing with the plasma membrane.

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    Facilitated Diffusion

    A type of membrane transport that requires the assistance of membrane proteins to move molecules across the cell membrane.

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    Channel-mediated transport

    A type of facilitated diffusion that involves membrane proteins forming hydrophilic channels through which molecules can pass. These channels are selective, allowing only specific molecules to pass through.

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    Active transport

    A type of membrane transport that utilizes energy to move molecules against their concentration gradient (from an area of low concentration to an area of high concentration).

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    Primary active transport

    A type of active transport that directly uses energy from ATP hydrolysis to move molecules across the membrane. It's like using a pump to move water uphill.

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    Secondary active transport (cotransport)

    A type of active transport that uses the energy stored in the electrochemical gradient of one molecule to move another molecule against its concentration gradient. It's coupling the movement of one molecule with the movement of another.

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    Symport

    A type of secondary active transport where two molecules move in the same direction across the membrane. One molecule moves down its concentration gradient, providing the energy for the other molecule to move against its concentration gradient.

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    Antiport

    A type of secondary active transport where two molecules move in opposite directions across the membrane. One molecule moves down its concentration gradient, providing the energy for the other molecule to move against its concentration gradient.

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    Food Vacuole Fusion

    The fusion of a food vacuole with a lysosome, an organelle containing enzymes that break down the engulfed material into usable components.

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    Coat Proteins

    Coat proteins that contribute to vesicle formation by shaping the vesicle and aiding its detachment from the membrane.

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    Vesicles

    Membrane-bound sacs that transport substances within and out of the cell, often formed by endocytosis or exocytosis.

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    Study Notes

    Cell Function - Membrane and Transport

    • The presentation covers the basic concepts of cell function, focusing on the membrane and transport mechanisms.
    • The learning objectives include summarizing membrane components and functions, comparing movement of small and large molecules across the plasma membrane, and differentiating between cell surface receptors.
    • The fluid mosaic model is the accepted structure of the plasma membrane, a mosaic of phospholipids, cholesterol, and proteins that move fluidly.
    • Key components of the plasma membrane include phospholipids (glycerol, fatty acid tails, phosphate head), cholesterol (four fused carbon rings), membrane proteins (extend partway, cross entirely, or are loosely attached), and carbohydrate groups (attached to proteins or lipids).
    • Phospholipids are amphipathic, meaning they have hydrophilic (water-loving) heads and hydrophobic (water-fearing) tails, creating a bilayer structure.
    • Hydrophilic heads face outward, while hydrophobic tails face inward, in an aqueous solution.
    • This arrangement creates a barrier to polar molecules and ions, contributing to selective permeability.
    • Cholesterol adds stability and fluidity to the membrane, adjusting fluidity across wide temperature ranges.
    • Membrane proteins include integral (penetrating the lipid bilayer) and peripheral (loosely bound) proteins. Integral proteins can act as channels or carriers.
    • Different types of cell surface receptors exist, including ion channel-linked, G-protein linked, and enzyme-linked receptors.
    • These receptors play vital roles in receiving and relaying signals from the cell exterior to the interior.

    Membrane Transport

    • Passive transport does not require energy and includes diffusion (movement down a concentration gradient) , facilitated diffusion (through membrane proteins) , channels (selective tunnels) and carrier proteins (change shape).
    • Selective permeability is a key property of cell membranes, with only specific substances passing through easily.
    • Diffusion is the spontaneous movement of substances from high concentration to low concentration until equilibrium is reached.
    • Facilitated diffusion utilizes membrane proteins to speed up the movement of specific substances down their concentration gradients.
    • Channels provide hydrophilic tunnels for specific ions and small polar molecules, while carrier proteins modify their shape to move molecules across the membrane.

    Active Transport

    • Active transport requires energy (ATP) to move substances against their concentration gradients.
    • Primary active transport directly uses ATP to move ions, like the sodium-potassium pump, which maintains cellular ion concentrations and voltage.
    • Secondary active transport (cotransport) uses the energy stored in ion gradients (established by primary active transport), such as the sodium gradient, to move other substances against their gradient (e.g., glucose).

    Bulk Transport

    • Bulk transport involves the movement of large particles or large quantities of smaller particles across the membrane via endocytosis (into the cell) or exocytosis (out of the cell).
    • Subtypes of endocytosis include phagocytosis (engulfing large particles), pinocytosis (engulfing fluids), and receptor-mediated endocytosis (using specific receptors for target molecules).
    • Vesicles are formed to enclose the transported material and are moved intracellularly by cytoskeletal elements.
    • Exocytosis involves fusing vesicles with the membrane to release their contents outside of the cell.

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    Description

    This quiz delves into the Fluid Mosaic Model of the plasma membrane, exploring its primary structure and the roles of various components such as phospholipids and cholesterol. Learn about how molecules traverse this essential barrier and the significance of hydrophilic and hydrophobic characteristics in membrane dynamics.

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