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Cell Biology Overview
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Cell Biology Overview

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What is the primary function of the rough endoplasmic reticulum (Rough ER)?

  • Synthesizes secretory proteins and adds carbohydrates to glycoproteins (correct)
  • Stores calcium ions
  • Produces energy in the form of ATP
  • Conducts cellular respiration
  • Which statement correctly describes the Golgi apparatus?

  • It transports ions into and out of the nucleus.
  • It is responsible for protein synthesis in the cytoplasm.
  • It consists of stacks of membranous sacs with polarity. (correct)
  • It degrades worn-out cellular components.
  • What process occurs in the Golgi apparatus involving carbohydrates?

  • Modification and addition of carbohydrates to proteins (correct)
  • Degradation of carbohydrates into simpler sugars
  • Synthesis of fatty acids
  • Transport of carbohydrates to the nucleus
  • What occurs at the trans face of the Golgi apparatus?

    <p>Sorting and packaging of proteins into vesicles</p> Signup and view all the answers

    Which of the following is NOT a function of the rough endoplasmic reticulum?

    <p>Modification of phospholipids</p> Signup and view all the answers

    What is the main function of the smooth endoplasmic reticulum?

    <p>Detoxification of drugs and poisons</p> Signup and view all the answers

    Which structure is continuous with the nuclear envelope?

    <p>Smooth endoplasmic reticulum</p> Signup and view all the answers

    What are ribosomes primarily composed of?

    <p>Ribosomal RNA and proteins</p> Signup and view all the answers

    What is the function of pores in the nuclear envelope?

    <p>Regulate materials entry and exit</p> Signup and view all the answers

    Where are ribosomal subunits made?

    <p>Nucleoli</p> Signup and view all the answers

    What is the primary function of lysosomes?

    <p>Breakdown of ingested substances</p> Signup and view all the answers

    Which structure is responsible for cellular respiration?

    <p>Mitochondrion</p> Signup and view all the answers

    What does the structure of a chloroplast typically include?

    <p>Two membranes and thylakoids</p> Signup and view all the answers

    What is a primary function of vacuoles in plant cells?

    <p>Digestion and storage</p> Signup and view all the answers

    Which of the following correctly describes the peroxisome's function?

    <p>Transfers hydrogen and produces hydrogen peroxide</p> Signup and view all the answers

    In eukaryotic cells, where are chromosomes housed?

    <p>Nucleus</p> Signup and view all the answers

    Which of these organelles is involved in photosynthesis?

    <p>Chloroplast</p> Signup and view all the answers

    What is the role of cristae in mitochondria?

    <p>Increase surface area for energy production</p> Signup and view all the answers

    Which component is associated with maintaining water balance in plant cells?

    <p>Vacuole</p> Signup and view all the answers

    What type of membrane bounds the nucleus?

    <p>Double membrane</p> Signup and view all the answers

    What characterizes prokaryotic cells?

    <p>DNA contained in a nucleoid region</p> Signup and view all the answers

    Which of the following structures is found in eukaryotic cells but not in prokaryotic cells?

    <p>Nucleus</p> Signup and view all the answers

    What is the primary function of the rough endoplasmic reticulum?

    <p>Protein synthesis</p> Signup and view all the answers

    Which organelle is involved in the modification and packaging of proteins?

    <p>Golgi apparatus</p> Signup and view all the answers

    What do lysosomes contain that aids in digestion?

    <p>Hydrolytic enzymes</p> Signup and view all the answers

    Which structure in the chloroplast is primarily involved in the light-dependent reactions of photosynthesis?

    <p>Thylakoids</p> Signup and view all the answers

    What is the function of the cytoskeleton?

    <p>Cell shape maintenance and organization</p> Signup and view all the answers

    Which component of the endomembrane system detoxifies poisons?

    <p>Smooth endoplasmic reticulum</p> Signup and view all the answers

    Why are mitochondria known as the 'powerhouses' of the cell?

    <p>They are involved in cellular respiration and ATP synthesis</p> Signup and view all the answers

    What process describes the recycling of a cell's own organelles by lysosomes?

    <p>Autophagy</p> Signup and view all the answers

    Which type of ribosome synthesizes proteins that are secreted from the cell?

    <p>Bound ribosomes</p> Signup and view all the answers

    What is the primary role of vacuoles in plant cells?

    <p>Storage of nutrients and waste products</p> Signup and view all the answers

    Which of the following statements about peroxisomes is correct?

    <p>They produce and break down hydrogen peroxide</p> Signup and view all the answers

    In eukaryotic cells, the nuclear envelope serves what primary function?

    <p>Protection of DNA from cytoplasmic enzymes</p> Signup and view all the answers

    What is the main function of the Rough Endoplasmic Reticulum?

    <p>Synthesis of secretory and other proteins</p> Signup and view all the answers

    What is the primary role of the Golgi apparatus?

    <p>Modifying proteins and sorting them for transport</p> Signup and view all the answers

    Which organelle is primarily responsible for the breakdown of macromolecules in animal cells?

    <p>Lysosome</p> Signup and view all the answers

    What is the primary function of mitochondria?

    <p>Cellular respiration</p> Signup and view all the answers

    What is unique about the structure of chloroplasts?

    <p>Bounded by a double membrane with thylakoids</p> Signup and view all the answers

    Which organelle is involved in the detoxification process within the cell?

    <p>Peroxisome</p> Signup and view all the answers

    What is the function of vacuoles in plant cells?

    <p>Digestion and storage</p> Signup and view all the answers

    How do the layers of the Golgi apparatus contribute to its function?

    <p>They ensure polarity for protein sorting.</p> Signup and view all the answers

    Which of the following best describes the Rough Endoplasmic Reticulum?

    <p>Synthesis of secretory proteins and glycoproteins</p> Signup and view all the answers

    What is the function of the infoldings (cristae) in mitochondria?

    <p>Increase surface area for ATP production</p> Signup and view all the answers

    Study Notes

    Overview: The Fundamental Units of Life

    • All living organisms are comprised of cells.
    • Cells are the simplest form of matter that can sustain life.
    • The structure of a cell is directly related to its function.
    • All cells descended from earlier cells.

    Comparing Prokaryotic and Eukaryotic Cells

    • All cells share the following features:
      • A plasma membrane
      • Cytosol, a semifluid substance
      • Chromosomes, which contain genes
      • Ribosomes, which synthesize proteins.
    • Prokaryotic cells are characterized by:
      • Lacking a nucleus
      • Having DNA located in a region called the nucleoid
      • Lacking other membrane-bound organelles
      • Having cytoplasm enclosed by the plasma membrane.
    • Eukaryotic cells are characterized by:
      • Having DNA contained within a nucleus bound by a nuclear envelope
      • Having other membrane-bound organelles
      • Having cytoplasm located between the plasma membrane and nucleus.
    • Generally, Eukaryotic cells are much larger than prokaryotic cells.

    The Nucleus: Information Central

    • The nucleus stores the majority of the eukaryotic cell's genetic information, making it the cell's most visible organelle.
    • The nuclear envelope encloses the nucleus, separating it from the cytoplasm.
    • This envelope is a double membrane structure; each membrane is made up of a lipid bilayer.
    • Pores within the membrane allow for the entry and exit of molecules.
    • The nucleus is maintained by the nuclear lamina, a network of protein filaments.
    • DNA, along with proteins, forms chromatin.
    • Chromatin condenses to form discrete chromosomes.
    • The nucleolus, found within the nucleus, synthesizes ribosomal RNA (rRNA).

    Ribosomes: Protein Factories

    • Ribosomes are composed of rRNA and protein.
    • Protein synthesis takes place at ribosomes, both freely in the cytosol or bound to the endoplasmic reticulum or nuclear envelope.

    The Endomembrane System: Regulating Protein Traffic and Metabolic Functions

    • The endomembrane system comprises a network of membranes and organelles within eukaryotic cells that function together to modify, package, and transport lipids and proteins.
    • These components are either continuous with one another, or connected via transfer by vesicles:
      • Nuclear envelope
      • Endoplasmic reticulum (ER)
      • Golgi apparatus
      • Lysosomes
      • Vacuoles
      • Plasma membrane

    The Endoplasmic Reticulum: Biosynthetic Factory

    • The ER accounts for more than half of the total membrane in eukaryotic cells.
    • ER is continuous with the nuclear envelope.
    • The ER is divided into two distinct regions:
      • Smooth ER: lacks ribosomes.
      • Rough ER: has ribosomes attached to its surface.

    Functions of Smooth ER

    • Synthesizes lipids.
    • Metabolizes carbohydrates.
    • Detoxifies poisons.
    • Stores calcium.

    Functions of Rough ER

    • Contains bound ribosomes, which secrete glycoproteins.
    • Distributes transport vesicles, proteins surrounded by membranes.
    • It is a membrane factory for the cell.

    The Golgi Apparatus: Shipping and Receiving Center

    • The Golgi apparatus comprises flattened membranous sacs called cisternae.
    • Its functions include:
      • Modifying products of the ER
      • Manufacturing certain macromolecules
      • Sorting and packaging materials into transport vesicles.

    Lysosomes: Digestive Compartments

    • A membranous sac of hydrolytic enzymes called a lysosome can digest macromolecules.
    • Lysosomal enzymes can degrade proteins, fats, polysaccharides, and nucleic acids.
    • Some cells engulf other cells by a process called phagocytosis, resulting in a food vacuole.
    • A lysosome fuses with the food vacuole and digests the molecules.
    • Lysosomes can recycle the cell's own organelles and macromolecules through autophagy.

    Vacuoles: Diverse Maintenance Compartments

    • Plant cells may have one or several vacuoles.
    • Food vacuoles are formed by phagocytosis.
    • Contractile vacuoles, found in many freshwater protists, pump out excess water.
    • Central vacuoles, present in mature plant cells, hold organic compounds and water.

    The Endomembrane System: A Review

    • The endomembrane system is a dynamic and complex component of the cell's compartmental organization.

    Mitochondria and Chloroplasts: Changing Energy Forms

    • Mitochondria are the location of cellular respiration, the metabolic pathway that generates ATP.
    • Chloroplasts, found in plants and algae, conduct photosynthesis.
    • Peroxisomes are oxidative organelles.
    • Mitochondria and chloroplasts:
      • Are not part of the endomembrane system
      • Have double membranes
      • Have proteins made by free ribosomes
      • Contain their own DNA

    Mitochondria: Chemical Energy Conversion

    • Mitochondria are present in nearly all eukaryotic cells.
    • They have a smooth outer membrane and an inner membrane folded into cristae.
    • The inner membrane creates two compartments: an intermembrane space and a mitochondrial matrix.
    • Metabolic steps in cellular respiration are catalyzed in the mitochondrial matrix.
    • Cristae provide a significant surface area for enzymes that synthesize ATP.

    Chloroplasts: Capture of Light Energy

    • Chloroplasts belong to a family of organelles known as plastids.
    • Chloroplasts contain chlorophyll, the green pigment essential for photosynthesis.
    • They also contain enzymes and other molecules involved in photosynthesis.
    • Chloroplasts are found in leaves and other green organs of plants and algae.

    Chloroplast Structure

    • Thylakoids are stacked membrane-bound compartments within chloroplasts, forming a granum.
    • Stroma is the internal fluid of the chloroplast.

    Peroxisomes: Oxidation

    • Peroxisomes are metabolic compartments surrounded by a single membrane.
    • They produce hydrogen peroxide and convert it to water.
    • They utilize oxygen to degrade various types of molecules.

    The Cytoskeleton: A Network of Fibers that Organizes Structures and Activities

    • The cytoskeleton extends throughout the cytoplasm as a network of fibers.
    • It organizes the cell's structure and activities, anchoring many organelles.
    • It is made up of three types of molecular structures:
      • Microtubules
      • Microfilaments
      • Intermediate filaments

    Cilia and Flagella

    • Microtubules control the beating of cilia and flagella, locomotor appendages of some cells.
    • Cilia and flagella differ in their beating patterns.
    • Cilia move in coordinated waves.
    • Flagella move in a whip-like motion.

    Extracellular Components and Connections Between Cells: Coordinating Cellular Activity

    • Most cells synthesize and secrete substances outside the plasma membrane.
    • These extracellular structures comprise:
      • The cell walls of plants
      • The extracellular matrix (ECM) of animal cells
      • Intercellular junctions

    Cell Walls of Plants

    • The cell wall, found only in plant cells, distinguishes them from animal cells.
    • Cell walls are also found in prokaryotes, fungi, and some protists.
    • The cell wall protects the plant cell, maintains its shape, and prevents excessive water uptake.
    • Plant cell walls are composed of cellulose fibers embedded in other polysaccharides and proteins.
    • Plant cell walls may include multiple layers:
      • Primary cell wall: relatively thin and flexible
      • Middle lamella: thin layer between primary walls of adjacent cells
      • Secondary cell wall: added between the primary cell wall and the plasma membrane.
    • Plasmodesmata are channels between neighboring plant cells.

    The Extracellular Matrix (ECM) of Animal Cells

    • Animal cells lack cell walls but are covered by an extracellular matrix (ECM), an elaborate layer.
    • The ECM contains glycoproteins, including collagen, proteoglycans, and fibronectin.
    • ECM proteins bind to receptor proteins, integrins, in the plasma membrane.

    Functions of the ECM:

    • Support and signaling
    • Adhesion
    • Movement
    • Regulation

    Intercellular Junctions

    • Intercellular junctions facilitate direct cell-cell contact, allowing cells in tissues, organs, or organ systems to adhere, interact, and communicate.
    • Types of intercellular junctions include:
      • Plasmodesmata (plant cells)
      • Tight junctions (animal cells)
      • Desmosomes (animal cells)
      • Gap junctions (animal cells)

    Nucleus

    • The nucleus is the control center of the cell, containing the cell's genetic material (DNA)
    • The nucleus is surrounded by a double membrane called the nuclear envelope
    • The nuclear envelope is perforated with nuclear pores, which regulate the movement of molecules between the nucleus and the cytoplasm
    • The nucleus contains nucleoli, where ribosomal subunits are assembled

    Ribosomes

    • Ribosomes are the protein synthesis machinery of the cell, made up of ribosomal RNA and proteins.
    • Ribosomes can be found in two locations: free in the cytoplasm or bound to the ER
    • Free ribosomes make proteins that function within the cytosol while bound ribosomes synthesize proteins that will be secreted from the cell or incorporated into membranes.

    Endoplasmic reticulum (ER)

    • The ER is an extensive network of membrane-bound tubules and sacs that is continuous with the nuclear envelope.
    • The ER is divided into two regions: smooth ER (SER) and rough ER (RER)

    Smooth ER

    • Synthesizes lipids, metabolizes carbohydrates, stores calcium ions, and detoxifies drugs and poisons

    Rough ER

    • Responsible for the synthesis of proteins, adds carbohydrates to glycoproteins, and produces new membranes

    Golgi apparatus

    • The Golgi apparatus consists of stacks of flattened membranous sacs called cisternae
    • It receives proteins and lipids from the ER and modifies, sorts, and packages them for secretion or delivery to other organelles
    • The Golgi apparatus also plays a role in the synthesis of polysaccharides.

    Lysosomes

    • Lysosomes are membrane-bound sacs that contain digestive enzymes
    • They break down ingested substances, cell macromolecules, and damaged organelles

    Vacuoles

    • Vacuoles are large membrane-bound vesicles found primarily in plant cells
    • They are responsible for storage, waste disposal, water balance, cell growth, and protection

    Mitochondria

    • Mitochondria are the powerhouses of the cell, responsible for cellular respiration, which generates ATP, the cell's primary energy currency
    • They are bounded by two membranes with the inner membrane folded into cristae

    Chloroplasts

    • Chloroplasts are found in plant cells and are the sites of photosynthesis, the process by which sunlight is converted into chemical energy
    • They are surrounded by two membranes and contain a fluid stroma, which contains membranous thylakoids stacked into grana

    Peroxisomes

    • Peroxisomes are metabolic compartments that contain enzymes that transfer hydrogen to water, producing hydrogen peroxide as a byproduct
    • Other enzymes within the peroxisome convert hydrogen peroxide to water

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