Cell Biology: Interphase Overview

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Questions and Answers

During which phase of mitosis do chromosomes become visible as thick threads or rods?

  • Metaphase
  • Prophase (correct)
  • Anaphase
  • Telophase

What is the primary function of mitosis?

  • To produce two genetically identical cells. (correct)
  • To facilitate cellular movement and separation, directly before cytokinesis.
  • To produce four genetically different gametes.
  • To reduce the number of chromosomes in a cell by half.

What is the literal meaning of the term 'cytokinesis'?

  • DNA replication
  • Cell separation or of cells moving apart (correct)
  • Nuclear division
  • Chromosome condensation

Which of the following best describes the duration of mitosis?

<p>It lasts for about 2 hours in most cases, but its duration varies and is cell-type dependent. (A)</p> Signup and view all the answers

When does cytokinesis begin in relation to the phases of mitosis?

<p>It starts during anaphase, as the chromosomes move apart. (D)</p> Signup and view all the answers

During which phase of interphase does DNA replication occur?

<p>S phase (C)</p> Signup and view all the answers

What is the main activity of a cell during the G1 phase of interphase?

<p>Rapid protein synthesis and cell growth (A)</p> Signup and view all the answers

What is the primary function of the G2 checkpoint in the cell cycle?

<p>To check for DNA damage and accuracy of replication (D)</p> Signup and view all the answers

Which event marks the end of interphase and prepares the cell for division?

<p>Completion of centriole copying (B)</p> Signup and view all the answers

In which phase of the cell cycle does mitosis occur?

<p>M phase (B)</p> Signup and view all the answers

What is the term for the division of the cell into two daughter cells?

<p>Cytokinesis (B)</p> Signup and view all the answers

Which type of cells typically cannot divide after they have fully matured?

<p>Nervous tissue cells (A)</p> Signup and view all the answers

What event happens first, during cell division?

<p>Mitosis (D)</p> Signup and view all the answers

Flashcards

What is G1 phase?

The first phase of interphase where the cell grows, synthesizes proteins, and makes new organelles.

What happens during the S phase?

The phase of interphase where the cell replicates its DNA, ensuring that each daughter cell receives a copy.

What is G2 phase?

The final phase of interphase where the cell synthesizes proteins and organelles needed for cell division.

What does the G1 checkpoint ensure?

A checkpoint in the cell cycle that monitors the cell's size and whether DNA synthesis is complete.

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What does the G2 checkpoint check for?

A checkpoint that checks for any damage to the DNA after replication.

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What is mitosis?

The process of dividing the cell's nucleus into two identical daughter nuclei.

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What is cytokinesis?

The process of dividing the cytoplasm and organelles of a cell into two daughter cells.

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Why is cell division important?

The process of cell division is essential for growth and repair of tissues.

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What happens during metaphase?

The phase of mitosis where the chromosomes line up in the middle of the cell. It's like getting ready for the big split.

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What happens during anaphase?

The phase of mitosis where the sister chromatids (identical copies of chromosomes) are pulled apart toward opposite poles of the cell, like a tug-of-war.

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How does cytokinesis occur?

The process by which a ring of contractile actin and myosin filaments in the center of the cell constricts to pinch the cell in two, like squeezing a balloon to create two balloons.

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Study Notes

Interphase

  • Interphase prepares cells for division, consisting of G1, S, and G2 subphases.
  • G1 (Gap 1): Metabolically active, rapid protein synthesis, and vigorous growth. Duration varies greatly, from hours in rapidly dividing cells to days or years in slow-dividing ones. Centriole replication begins near the end of G1.
  • S (Synthetic) phase: DNA replicates, ensuring identical genetic material in daughter cells.
  • G2 (Gap 2): Brief; synthesis of enzymes needed for cell division. Centriole replication finishes. Cell is ready to divide.
  • Throughout all three subphases, the cell grows, produces proteins and organelles, and performs normal metabolic activities.
  • Checkpoints (throughout the cell cycle) assess cell activity, including growth, DNA replication, and spindle formation.
    • G1 checkpoint assesses cell size prior to DNA synthesis.
    • G2 checkpoint checks DNA damage and replication accuracy.
  • Mutations in genes at these checkpoints can cause uncontrolled division and tumor growth.

Cell Division

  • Essential for body growth and tissue repair.
  • Different cell types have varying division rates.
    • Short-lived cells (e.g., skin, intestinal) divide continuously.
    • Some cells (e.g., liver) divide slowly but rapidly if damaged.
    • Specialized cells (e.g., nervous, most muscle) cannot divide after maturation.
  • Division occurs in the M (mitotic) phase following interphase.
  • Most cell types divide through mitosis (nucleus division) and cytokinesis (cell division).

Mitosis

  • Replicated DNA from the original cell is divided into two new cells.
  • Chromosomes are evident as thick rods or threads.
  • A continuous process described in four phases: prophase, metaphase, anaphase, and telophase.
  • Typically lasts about 2 hours, but duration varies by cell type.

Cytokinesis

  • Separation of one cell into two at the end of the cell cycle. Begins during anaphase and finishes after mitosis.
  • Actin and myosin filaments constrict to pinch the cell in two.
  • The two new "daughter cells" enter interphase.

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