Cell Biology: Chromatin Types

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Questions and Answers

What is the main function of the nuclear pore complex?

  • Protein synthesis
  • Nucleocytoplasmic trafficking (correct)
  • DNA replication
  • Chromatin condensation

What is the composition of the chromatin?

  • RNA and lipids
  • DNA only
  • Proteins only
  • DNA and proteins (correct)

What is the function of the nuclear lamina?

  • Facilitating nuclear transport
  • Regulating gene expression
  • Modulating chromatin structure
  • Supporting the nuclear envelope (correct)

What is the characteristic of heterochromatin?

<p>Highly condensed and gene-poor (B)</p> Signup and view all the answers

What is the relationship between the nuclear envelope and the RER?

<p>The nuclear envelope is continuous with the RER (C)</p> Signup and view all the answers

What is the role of the perinuclear space?

<p>Separating the two concentric membranes (C)</p> Signup and view all the answers

What is the characteristic of the nucleoporin proteins?

<p>They are lipid-free and integral (C)</p> Signup and view all the answers

What is the association between the nuclear envelope and ribosomes?

<p>Due to the cell's economy (A)</p> Signup and view all the answers

What is the primary function of the G2 phase in the cell cycle?

<p>Error correction and repair (A)</p> Signup and view all the answers

What is the main difference between mitosis and meiosis?

<p>Number of chromosomes produced (C)</p> Signup and view all the answers

What is the role of cyclins and CDKs in the cell cycle?

<p>To regulate checkpoint proteins (A)</p> Signup and view all the answers

What occurs during apoptosis?

<p>Organized degradation of cellular organelles (C)</p> Signup and view all the answers

What is the function of checkpoint proteins in the cell cycle?

<p>To ensure the accuracy of DNA replication (D)</p> Signup and view all the answers

What is the primary function of stem cells?

<p>To differentiate into specific cell types (D)</p> Signup and view all the answers

What is the purpose of the G1 phase in the cell cycle?

<p>To prepare for cell division (D)</p> Signup and view all the answers

What happens to cells that undergo cell cycle arrest?

<p>They remain in a dormant state (A)</p> Signup and view all the answers

What is the primary difference between extrinsic apoptosis and intrinsic apoptosis?

<p>Extrinsic apoptosis is triggered by external stimuli, whereas intrinsic apoptosis is triggered by internal signals. (C)</p> Signup and view all the answers

What is the function of cytochrome C in intrinsic apoptosis?

<p>It activates caspases to initiate apoptosis. (D)</p> Signup and view all the answers

What is the primary difference between apoptosis and necrosis?

<p>Apoptosis is a programmed cell death, whereas necrosis is a random cell death. (A)</p> Signup and view all the answers

What is the function of the cell membrane during apoptosis?

<p>It forms apoptotic bodies that are removed by macrophages. (B)</p> Signup and view all the answers

What is the primary difference between mitosis and meiosis?

<p>Mitosis results in genetically identical daughter cells, whereas meiosis results in genetically unique daughter cells. (A)</p> Signup and view all the answers

What is the fate of the nucleus during apoptosis?

<p>It becomes fragmented and is distributed into the blebs. (D)</p> Signup and view all the answers

What is the significance of apoptotic bodies?

<p>They are functional and can survive for a short period of time. (C)</p> Signup and view all the answers

What is the role of caspases in apoptosis?

<p>They execute the apoptotic program by cleaving specific target proteins. (B)</p> Signup and view all the answers

What is the primary function of Constitutive Heterochromatin?

<p>To provide structural support (D)</p> Signup and view all the answers

What is the role of Histone H1 in nucleosome formation?

<p>Coiling helically around H2A, H2B, H3, and H4 (B)</p> Signup and view all the answers

What is the characteristic of Facultative Heterochromatin?

<p>It can be either condensed or decondensed (A)</p> Signup and view all the answers

Where is rRNA synthesized, processed, and complexed into ribosomal subunits?

<p>In the nucleus (D)</p> Signup and view all the answers

What is the function of the Nucleolus?

<p>To transcribe, process, and complex rRNA into ribosomal subunits (C)</p> Signup and view all the answers

What is the main component of Euchromatin?

<p>Gene-rich regions (B)</p> Signup and view all the answers

What is the fate of newly organized small and large ribosomal subunits?

<p>They are exported back into the cytoplasm (B)</p> Signup and view all the answers

What is the characteristic of Nucleosomes?

<p>They contain 4 pairs of histones (B)</p> Signup and view all the answers

What is the primary purpose of Meiosis?

<p>To cut the number of chromosomes per cell in half (B)</p> Signup and view all the answers

What occurs during Anaphase of cell division?

<p>Centromeres divide, and homologous chromosomes are separated (D)</p> Signup and view all the answers

What is the main difference between a Haploid cell and a Diploid cell?

<p>A Haploid cell has one set of chromosomes, while a Diploid cell has two sets (D)</p> Signup and view all the answers

What is the purpose of Prophase in cell division?

<p>To condense chromosomes and break down the nuclear envelope (B)</p> Signup and view all the answers

What occurs during Meiosis 1?

<p>DNA replication takes place, and homologous chromosomes are separated (A)</p> Signup and view all the answers

What is the purpose of Telophase in cell division?

<p>To decondense chromosomes and reappear the nuclear envelope (A)</p> Signup and view all the answers

What is the primary function of the spindle fibers during cell division?

<p>To attach to centromeres and separate sister chromatids (A)</p> Signup and view all the answers

What is the result of Meiosis 2?

<p>Two haploid cells each having 23 chromosomes of one chromatid (C)</p> Signup and view all the answers

Flashcards

What is the main function of the nuclear pore complex?

The movement of molecules between the nucleus and cytoplasm.

What is the composition of the chromatin?

DNA and proteins.

What is the function of the nuclear lamina?

Supporting the nuclear envelope, providing structural integrity.

What is the characteristic of heterochromatin?

Highly condensed and gene-poor.

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What is the characteristic of the nucleoporin proteins?

They are lipid-free and integral to the nuclear envelope.

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What is the relationship between the nuclear envelope and the RER?

The nuclear envelope is continuous with the RER, sharing a common membrane.

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What is the role of the perinuclear space?

Separating the two concentric membranes of the nuclear envelope.

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What is the association between the nuclear envelope and ribosomes?

The economy of the cell dictates this association, reducing energy expenditure.

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What is the primary function of the G2 phase in the cell cycle?

To complete DNA replication, check and repair any errors, and prepare for cell division.

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What is the main difference between mitosis and meiosis?

The number of chromosomes produced in the daughter cells.

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What is the role of cyclins and CDKs in the cell cycle?

To regulate checkpoint proteins which ensure the accuracy of the cell cycle.

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What occurs during apoptosis?

The process of programmed cell death or self-destruction.

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What is the function of checkpoint proteins in the cell cycle?

To ensure the accuracy of DNA replication, preventing errors and mutations.

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What is the primary function of stem cells?

To divide and differentiate into various types of specialized cells.

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What is the purpose of the G1 phase in the cell cycle?

To prepare for cell division by growing and synthesizing essential proteins.

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What happens to cells that undergo cell cycle arrest?

They remain in a dormant state, pausing their activity until needed.

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What is the primary difference between extrinsic apoptosis and intrinsic apoptosis?

Extrinsic apoptosis is triggered by external stimuli, whereas intrinsic apoptosis is triggered by internal signals.

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What is the function of cytochrome C in intrinsic apoptosis?

It activates caspases, initiating a cascade of events leading to apoptosis.

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What is the primary difference between apoptosis and necrosis?

Apoptosis is a programmed cell death, whereas necrosis is a random cell death.

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What is the function of the cell membrane during apoptosis?

It forms apoptotic bodies that are removed by macrophages to prevent inflammation.

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What is the primary difference between mitosis and meiosis?

Mitosis results in genetically identical daughter cells, whereas meiosis results in genetically unique daughter cells.

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What is the fate of the nucleus during apoptosis?

It becomes fragmented and is distributed into the blebs, which are eventually engulfed by macrophages.

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What is the significance of apoptotic bodies?

They are functional and contain a variety of cell components which can be recycled by macrophages.

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What is the role of caspases in apoptosis?

They execute the apoptotic program by cleaving specific target proteins, leading to cell disassembly.

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What is the primary function of Constitutive Heterochromatin?

To provide structural support and to hold DNA in a condensed state.

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What is the role of Histone H1 in nucleosome formation?

Coiling helically around H2A, H2B, H3, and H4 histones, helping to compact the DNA.

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What is the characteristic of Facultative Heterochromatin?

It can be either condensed or decondensed, depending on the activity of the genes it contains.

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Where is rRNA synthesized, processed, and complexed into ribosomal subunits?

It is the site where rRNA is synthesized, processed, and complexed into ribosomal subunits.

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What is the function of the Nucleolus?

To transcribe, process, and complex rRNA into ribosomal subunits, essential for protein synthesis.

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What is the main component of Euchromatin?

Gene-rich regions, meaning they contain active genes that are frequently transcribed.

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What is the fate of newly organized small and large ribosomal subunits?

They are exported back into the cytoplasm to carry out protein synthesis.

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What is the characteristic of Nucleosomes?

They contain 4 pairs of histones that are wrapped around by the DNA to form a compact structure.

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What is the primary purpose of Meiosis?

To reduce the number of chromosomes per cell in half, creating gametes for sexual reproduction.

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What occurs during Anaphase of cell division?

Centromeres divide, and homologous chromosomes are separated, resulting in two distinct sets of chromosomes.

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What is the main difference between a Haploid cell and a Diploid cell?

A Haploid cell has one set of chromosomes, while a Diploid cell has two sets.

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What is the purpose of Prophase in cell division?

To condense chromosomes, making them visible under a microscope, and break down the nuclear envelope.

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What occurs during Meiosis 1?

DNA replication takes place, and homologous chromosomes pair up and exchange genetic material (crossing over).

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What is the purpose of Telophase in cell division?

To decondense chromosomes, allowing them to relax and become less visible, and to reassemble the nuclear envelope.

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What is the primary function of the spindle fibers during cell division?

To attach to centromeres and separate sister chromatids, ensuring that each daughter cell receives a full set of chromosomes.

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What is the result of Meiosis 2?

Two haploid cells each having 23 chromosomes, one from each pair.

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