Cell Biology: Apoptosis and Cell Injury
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Questions and Answers

What is the process of programmed cell death characterized by cell shrinkage, chromatin condensation, and DNA fragmentation?

  • Autophagy
  • Necrosis
  • Apoptosis (correct)
  • Inflammation

What is the term for unprogrammed cell death resulting from injury or disease?

  • Autophagy
  • Apoptosis
  • Infection
  • Necrosis (correct)

What is the cellular process that involves the formation of autophagosomes to recycle damaged or dysfunctional organelles and proteins?

  • Necrosis
  • Apoptosis
  • Autophagy (correct)
  • Inflammation

What is the consequence of necrosis?

<p>Inflammation and tissue damage (C)</p> Signup and view all the answers

What is the benefit of apoptosis?

<p>Eliminates damaged cells, preventing cancer (C)</p> Signup and view all the answers

What is the benefit of autophagy?

<p>Maintains cellular homeostasis (A)</p> Signup and view all the answers

What is the primary function of the mitochondria in a cell?

<p>To produce ATP through aerobic cellular respiration (C)</p> Signup and view all the answers

Which organelle is responsible for removing waste products from the cell?

<p>Lysosomes (A)</p> Signup and view all the answers

What is the primary function of the cell membrane?

<p>To control the movement of substances into and out of the cell (C)</p> Signup and view all the answers

What is the term for the basic building blocks of life that group together to form tissues?

<p>Cells (D)</p> Signup and view all the answers

What is the result of the process of cellular respiration in the mitochondria?

<p>The production of ATP (C)</p> Signup and view all the answers

What is the primary function of ATP in the cell?

<p>To power cellular processes such as active transport, chemical work, and mechanical work (B)</p> Signup and view all the answers

What is the result of glycolysis in the process of aerobic respiration?

<p>The breakdown of glucose into 2 pyruvate molecules and the yield of 2 ATP molecules (B)</p> Signup and view all the answers

What is the main difference between intracellular fluid (ICF) and extracellular fluid (ECF)?

<p>ICF is found inside the cell, while ECF is found outside the cell (D)</p> Signup and view all the answers

What is the role of ATP in maintaining ion concentration gradients across the cell membrane?

<p>To move ions against their concentration gradient (C)</p> Signup and view all the answers

What is the characteristic of the concentration gradient of sodium ions across the cell membrane?

<p>The concentration of sodium ions is higher in the ECF (C)</p> Signup and view all the answers

Study Notes

Cell Adaptation and Injury

Apoptosis

  • Programmed cell death, a natural process to eliminate damaged or unwanted cells
  • Also known as "cell suicide"
  • Characterized by:
    • Cell shrinkage
    • Chromatin condensation
    • DNA fragmentation
    • Formation of apoptotic bodies
  • Induced by:
    • DNA damage
    • Oxidative stress
    • Hormonal changes
    • Infections
  • Benefits:
    • Eliminates damaged cells, preventing cancer
    • Helps regulate tissue development and homeostasis
    • Removes infected cells, preventing disease spread

Necrosis

  • Unprogrammed cell death, resulting from injury or disease
  • Characterized by:
    • Cell swelling
    • Plasma membrane rupture
    • Release of cellular contents
    • Inflammation
  • Caused by:
    • Ischemia (lack of blood flow)
    • Toxins
    • Infections
    • Trauma
  • Consequences:
    • Inflammation and tissue damage
    • Can lead to disease and organ dysfunction

Autophagy

  • Cellular process for recycling damaged or dysfunctional organelles and proteins
  • Involves:
    • Formation of autophagosomes (membrane-bound structures)
    • Fusion with lysosomes
    • Degradation of contents
  • Induced by:
    • Starvation
    • Oxidative stress
    • Infections
    • Cancer
  • Benefits:
    • Maintains cellular homeostasis
    • Helps remove damaged or infected cells
    • Promotes cell survival during stress

Note: These notes focus on the key concepts and differences between apoptosis, necrosis, and autophagy. For a more detailed understanding, additional resources may be necessary.

Cell Adaptation and Injury

Apoptosis

  • Programmed cell death, a natural process to eliminate damaged or unwanted cells, also known as "cell suicide"
  • Characterized by cell shrinkage, chromatin condensation, DNA fragmentation, and formation of apoptotic bodies
  • Induced by DNA damage, oxidative stress, hormonal changes, and infections
  • Benefits: eliminates damaged cells, preventing cancer; helps regulate tissue development and homeostasis; removes infected cells, preventing disease spread

Necrosis

  • Unprogrammed cell death, resulting from injury or disease
  • Characterized by cell swelling, plasma membrane rupture, release of cellular contents, and inflammation
  • Caused by ischemia, toxins, infections, and trauma
  • Consequences: inflammation and tissue damage; can lead to disease and organ dysfunction

Autophagy

  • Cellular process for recycling damaged or dysfunctional organelles and proteins
  • Involves formation of autophagosomes, fusion with lysosomes, and degradation of contents
  • Induced by starvation, oxidative stress, infections, and cancer
  • Benefits: maintains cellular homeostasis; helps remove damaged or infected cells; promotes cell survival during stress

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Learn about apoptosis, a natural process of programmed cell death, its characteristics, benefits and inducing factors. Understand its role in eliminating damaged cells, preventing cancer and regulating tissue development.

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