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Cell Apoptosis vs Myelination Quiz

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Questions and Answers

What is the role of caspases in apoptosis?

Serving as key components in the apoptotic signaling network (correct)

Reducing blood flow to the brain

Impeding the development of white matter

Enhancing the speed of information transmission

How does myelination impact the transmission of information along neurons?

It increases the number of neurons within the cortex

It reduces spine density

It impairs brain connectivity

It enhances the speed and fidelity of information encoded in action potentials (correct)

What factor can cause a reduction in blood flow combined with lower than normal oxygen levels in the blood, ultimately affecting brain development?

Maternal stress

Intrauterine infection/inflammation

Premature birth

Cerebral hypoxia-ischemia (correct)

What neurological disorder may have its origins during fetal life according to compelling evidence?

Cerebral palsy (B) Signup and view all the answers

What is a potential consequence of acute fetal hypoxemia on brain development?

Enhanced cell migration in the hippocampus (C) Signup and view all the answers

What effect can chronic fetal hypoxemia have on brain development?

Impairment of development of the fetus (C) Signup and view all the answers

How can CNS inflammation affect pre-oligodendrocytes?

Impeding interneuron axons survival (D) Signup and view all the answers

What is a potential therapeutic intervention for injuries unfolding over several days after an insult?

Stem cells with neuroprotective effects (C) Signup and view all the answers

What challenges are associated with cord blood cell therapy?

Transient neuroprotective effects (B) Signup and view all the answers

What is the main focus of preclinical considerations relating to humans according to the text?

Relevance to humans (A) Signup and view all the answers