CBMBP Semester 6: IV Thrombolysis in Ischemic Stroke
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Questions and Answers

What is the definition of acute cerebrovascular stroke?

  • An episode of symptomatic neurological dysfunction caused by focal brain, retinal or spinal cord ischemia or hemorrhage with evidence of acute infarction or hemorrhage on imaging. (correct)
  • A condition where the brain is deprived of oxygen for an extended period of time.
  • A type of stroke that occurs gradually over a period of weeks or months.
  • A sudden loss of consciousness due to a lack of blood flow to the brain.

    • What happens to the brain every minute during an acute ischemic stroke?

  • The brain loses 1 million neurons, 7 billion synapses, and 3.5 miles of myelinated fibers, aging by 1.5 weeks.
  • The brain loses 2 million neurons, 14 billion synapses, and 7.5 miles of myelinated fibers, aging by 3.1 weeks. (correct)
  • The brain loses 3 million neurons, 18 billion synapses, and 9 miles of myelinated fibers, aging by 4 weeks.
  • The brain loses 5 million neurons, 20 billion synapses, and 10 miles of myelinated fibers, aging by 5 weeks.

    • When was IV thrombolysis (IVT) approved by the FDA for the treatment of acute ischemic stroke?

  • 2006
  • 1996 (correct)
  • 1986
  • 2016

    • What percentage of acute ischemic stroke (AIS) patients receive IV thrombolysis (IVT) within the first 60 minutes?

    <p>Less than 1.4%</p> Signup and view all the answers

    What is the major obstacle interfering with the proper utilization of IV thrombolysis (IVT) for acute ischemic stroke?

    <p>The narrow therapeutic window and decreased efficacy over time.</p> Signup and view all the answers

    What organization considered IV thrombolysis (IVT) as one of the opportunity drugs?

    <p>The World Health Organization (WHO)</p> Signup and view all the answers

    According to the information provided, what is one of the causes of prehospital delay in the arrival of stroke patients?

    <p>Marked delay in onset to door time</p> Signup and view all the answers

    Which of the following is a requirement for an efficient stroke chain?

    <p>Training all medical and paramedical stroke concerned staff</p> Signup and view all the answers

    According to the information provided, what is the best dispatch decision after vital signs stability?

    <p>Administer intravenous thrombolysis (IVT) before ICU disposition</p> Signup and view all the answers

    Which of the following strategies could help reduce the door-to-needle time for stroke patients?

    <p>Attaining all pre-injection steps concurrently rather than consecutively</p> Signup and view all the answers

    Based on the information provided, what was one of the impacts of the COVID-19 pandemic on stroke services?

    <p>Many members of the stroke team (doctors, nurses, and paramedics) contracted COVID-19 during their duties</p> Signup and view all the answers

    According to the graph, which quarter of 2020 had the highest number of stroke cases?

    <p>Q1</p> Signup and view all the answers

    Which study was published in the European Journal of Neurology in 2018?

    <p>Meschia et al.</p> Signup and view all the answers

    In which journal did Fernandes et al. publish their work in 2016?

    <p>BMJ</p> Signup and view all the answers

    Who authored the study with the doi: 10.1161/CIRCRESAHA.116.308413 in 2017?

    <p>Fonarow et al.</p> Signup and view all the answers

    Where was the study by Paul et al. published in 2016?

    <p>BMJ</p> Signup and view all the answers

    Which author's work is referenced by the doi: 10.4061/2011/686797 in 2011?

    <p>Ghandehari et al.</p> Signup and view all the answers

    Who are the authors of the study with doi: 10.1159/000444175 in 2016?

    <p>Valenzuela et al.</p> Signup and view all the answers

    What is the first step in the chain for fast recognition and treatment of acute ischemic stroke (AIS) patients?

    <p>Detection - Early recognition of stroke symptoms</p> Signup and view all the answers

    Which of the following is NOT a potential barrier to timely treatment of acute ischemic stroke?

    <p>Rapid transport to the nearest stroke-ready hospital</p> Signup and view all the answers

    What is the step in the stroke chain of survival that involves administering appropriate drug interventions?

    <p>Drug - Administration of appropriate drug interventions in the appropriate time</p> Signup and view all the answers

    Which of the following is NOT listed as a potential barrier to timely treatment of acute ischemic stroke?

    <p>Administering thrombolytic therapy within the time window</p> Signup and view all the answers

    What is the final step in the stroke chain of survival?

    <p>Disposition - Final admission in stroke intensive care unit or other</p> Signup and view all the answers

    Which of the following is a potential barrier to timely treatment of acute ischemic stroke related to the diagnostic process?

    <p>Failure to diagnose non-motor stroke</p> Signup and view all the answers

    What is one of the key aspects highlighted for effective stroke management?

    <p>Raising public awareness about recognizing early stroke symptoms</p> Signup and view all the answers

    Which of the following statements accurately describes the population density in Gharbia?

    <p>Gharbia has a high population density of approximately 10,000 people per square kilometer</p> Signup and view all the answers

    Which of the following services or facilities is NOT mentioned as being available at Tanta University Hospitals?

    <p>Dedicated stroke rehabilitation center</p> Signup and view all the answers

    According to the information provided, what is the approximate population size served by Tanta University Hospitals for stroke care?

    <p>10 million Egyptian citizens</p> Signup and view all the answers

    Which of the following measures is highlighted as part of the organized protocol for early stroke management?

    <p>Unifying the stroke pathway and centralizing services in one building</p> Signup and view all the answers

    Based on the information provided, which statement is true regarding the medical services in Egypt?

    <p>The medical services are under the management of different agencies and ministries</p> Signup and view all the answers

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