CBMBP Semester 6: IV Thrombolysis in Ischemic Stroke

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What is the definition of acute cerebrovascular stroke?

An episode of symptomatic neurological dysfunction caused by focal brain, retinal or spinal cord ischemia or hemorrhage with evidence of acute infarction or hemorrhage on imaging. (correct)

A condition where the brain is deprived of oxygen for an extended period of time.

A type of stroke that occurs gradually over a period of weeks or months.

A sudden loss of consciousness due to a lack of blood flow to the brain.

What happens to the brain every minute during an acute ischemic stroke?

The brain loses 1 million neurons, 7 billion synapses, and 3.5 miles of myelinated fibers, aging by 1.5 weeks.

The brain loses 2 million neurons, 14 billion synapses, and 7.5 miles of myelinated fibers, aging by 3.1 weeks. (correct)

The brain loses 3 million neurons, 18 billion synapses, and 9 miles of myelinated fibers, aging by 4 weeks.

The brain loses 5 million neurons, 20 billion synapses, and 10 miles of myelinated fibers, aging by 5 weeks.

When was IV thrombolysis (IVT) approved by the FDA for the treatment of acute ischemic stroke?

2006

1996 (correct)

1986

2016

What percentage of acute ischemic stroke (AIS) patients receive IV thrombolysis (IVT) within the first 60 minutes?

Less than 1.4% Signup and view all the answers

What is the major obstacle interfering with the proper utilization of IV thrombolysis (IVT) for acute ischemic stroke?

The narrow therapeutic window and decreased efficacy over time. Signup and view all the answers

What organization considered IV thrombolysis (IVT) as one of the opportunity drugs?

The World Health Organization (WHO) Signup and view all the answers

According to the information provided, what is one of the causes of prehospital delay in the arrival of stroke patients?

Marked delay in onset to door time Signup and view all the answers

Which of the following is a requirement for an efficient stroke chain?

Training all medical and paramedical stroke concerned staff Signup and view all the answers

According to the information provided, what is the best dispatch decision after vital signs stability?

Administer intravenous thrombolysis (IVT) before ICU disposition Signup and view all the answers

Which of the following strategies could help reduce the door-to-needle time for stroke patients?

Attaining all pre-injection steps concurrently rather than consecutively Signup and view all the answers

Based on the information provided, what was one of the impacts of the COVID-19 pandemic on stroke services?

Many members of the stroke team (doctors, nurses, and paramedics) contracted COVID-19 during their duties Signup and view all the answers

According to the graph, which quarter of 2020 had the highest number of stroke cases?

Q1 Signup and view all the answers

Which study was published in the European Journal of Neurology in 2018?

Meschia et al. Signup and view all the answers

In which journal did Fernandes et al. publish their work in 2016?

BMJ Signup and view all the answers

Who authored the study with the doi: 10.1161/CIRCRESAHA.116.308413 in 2017?

Fonarow et al. Signup and view all the answers

Where was the study by Paul et al. published in 2016?

BMJ Signup and view all the answers

Which author's work is referenced by the doi: 10.4061/2011/686797 in 2011?

Ghandehari et al. Signup and view all the answers

Who are the authors of the study with doi: 10.1159/000444175 in 2016?

Valenzuela et al. Signup and view all the answers

What is the first step in the chain for fast recognition and treatment of acute ischemic stroke (AIS) patients?

Detection - Early recognition of stroke symptoms Signup and view all the answers

Which of the following is NOT a potential barrier to timely treatment of acute ischemic stroke?

Rapid transport to the nearest stroke-ready hospital Signup and view all the answers

What is the step in the stroke chain of survival that involves administering appropriate drug interventions?

Drug - Administration of appropriate drug interventions in the appropriate time Signup and view all the answers

Which of the following is NOT listed as a potential barrier to timely treatment of acute ischemic stroke?

Administering thrombolytic therapy within the time window Signup and view all the answers

What is the final step in the stroke chain of survival?

Disposition - Final admission in stroke intensive care unit or other Signup and view all the answers

Which of the following is a potential barrier to timely treatment of acute ischemic stroke related to the diagnostic process?

Failure to diagnose non-motor stroke Signup and view all the answers

What is one of the key aspects highlighted for effective stroke management?

Raising public awareness about recognizing early stroke symptoms Signup and view all the answers

Which of the following statements accurately describes the population density in Gharbia?

Gharbia has a high population density of approximately 10,000 people per square kilometer Signup and view all the answers

Which of the following services or facilities is NOT mentioned as being available at Tanta University Hospitals?

Dedicated stroke rehabilitation center Signup and view all the answers

According to the information provided, what is the approximate population size served by Tanta University Hospitals for stroke care?

10 million Egyptian citizens Signup and view all the answers

Which of the following measures is highlighted as part of the organized protocol for early stroke management?

Unifying the stroke pathway and centralizing services in one building Signup and view all the answers

Based on the information provided, which statement is true regarding the medical services in Egypt?

The medical services are under the management of different agencies and ministries Signup and view all the answers